In Vitro Testing of an Implantable Wireless Telemetry System for Long-Term Electromyography Recordings in Large Animals

2015 ◽  
Vol 39 (10) ◽  
pp. 897-902 ◽  
Author(s):  
Lukas Kneisz ◽  
Ewald Unger ◽  
Hermann Lanmüller ◽  
Winfried Mayr
Keyword(s):  
Telemetry System ◽  
In Vitro Testing ◽  
Wireless Telemetry ◽  
Large Animals

scholarly journals Small-Scale Fluidized Bed Bioreactor for Long-Term Dynamic Culture of 3D Cell Constructs and in vitro Testing

2020 ◽  
Vol 8 ◽  
Author(s):  
Joana Mendonça da Silva ◽  
Eloy Erro ◽  
Maooz Awan ◽  
Sherri-Ann Chalmers ◽  
Barry Fuller ◽  
...  
Keyword(s):  
Fluidized Bed ◽  
Small Scale ◽  
In Vitro Testing ◽  
Fluidized Bed Bioreactor ◽  
Dynamic Culture

Effect of Long-Term In Vitro Testing on the Properties of Bioactive Glass−Polysulfone Composites

2010 ◽  
Vol 11 (3) ◽  
pp. 657-665 ◽  
Author(s):  
Rodrigo Oréfice ◽  
Jon West ◽  
Guy LaTorre ◽  
Larry Hench ◽  
Anthony Brennan
Keyword(s):  
Bioactive Glass ◽  
In Vitro Testing

The use of flow cytometric methods in acute and long-term in vitro testing

2005 ◽  
Vol 19 (7) ◽  
pp. 845-852 ◽  
Author(s):  
Helga Tuschl ◽  
Christina E. Schwab
Keyword(s):  
In Vitro Testing ◽  
Flow Cytometric

Vienna 2.2 knee joint simulator for long term in vitro testing

2006 ◽  
Vol 39 ◽  
pp. S50 ◽  
Author(s):  
G. von Skrbensky ◽  
R. Huber
Keyword(s):  
Knee Joint ◽  
In Vitro Testing

Simplified Pulse Reactor for Real-Time Long-Term In Vitro Testing of Biological Heart Valves

2010 ◽  
Vol 38 (5) ◽  
pp. 1919-1927 ◽  
Author(s):  
Martina Schleicher ◽  
Günther Sammler ◽  
Michael Schmauder ◽  
Olaf Fritze ◽  
Agnes J. Huber ◽  
...  
Keyword(s):  
Real Time ◽  
Heart Valves ◽  
In Vitro Testing ◽  
Pulse Reactor

Ultrastructural investigations of MDL 19,660-induced effects on the canine platelet and megakaryocyte

1990 ◽  
Vol 48 (3) ◽  
pp. 374-375
Author(s):  
D.E. Loudy ◽  
J. Sprinkle-Cavallo ◽  
J.T. Yarrington ◽  
F.Y. Thompson ◽  
J.P. Gibson
Keyword(s):  
Antidepressant Drug ◽  
Beagle Dogs ◽  
Long Term Effects ◽  
Short Term ◽  
Platelet Counts ◽  
Toxicological Studies ◽  
Induced Aggregation ◽  
Internal Architecture

Previous short term toxicological studies of one to two weeks duration have demonstrated that MDL 19,660 (5-(4-chlorophenyl)-2,4-dihydro-2,4-dimethyl-3Hl, 2,4-triazole-3-thione), an antidepressant drug, causes a dose-related thrombocytopenia in dogs. Platelet counts started to decline after two days of dosing with 30 mg/kg/day and continued to decrease to their lowest levels by 5-7 days. The loss in platelets was primarily of the small discoid subpopulation. In vitro studies have also indicated that MDL 19,660: does not spontaneously aggregate canine platelets and has moderate antiaggregating properties by inhibiting ADP-induced aggregation. The objectives of the present investigation of MDL 19,660 were to evaluate ultrastructurally long term effects on platelet internal architecture and changes in subpopulations of platelets and megakaryocytes.Nine male and nine female beagle dogs were divided equally into three groups and were administered orally 0, 15, or 30 mg/kg/day of MDL 19,660 for three months. Compared to a control platelet range of 353,000- 452,000/μl, a doserelated thrombocytopenia reached a maximum severity of an average of 135,000/μl for the 15 mg/kg/day dogs after two weeks and 81,000/μl for the 30 mg/kg/day dogs after one week.

Human thymic epithelial cells maintain long-term survival of clonogenic myeloid and erythroid progenitor cells in vitro

2000 ◽  
Vol 111 (1) ◽  
pp. 363-370 ◽  
Author(s):  
Katsuto Takenaka ◽  
Mine Harada ◽  
Tomoaki Fujisaki ◽  
Koji Nagafuji ◽  
Shinichi Mizuno ◽  
...  
Keyword(s):  
Epithelial Cells ◽  
Progenitor Cells ◽  
Thymic Epithelial Cells ◽  
Erythroid Progenitor ◽  
Term Survival ◽  
Long Term Survival ◽  
Erythroid Progenitor Cells

Human liver cell cultivation for long-term in vitro toxicity studies in a miniaturized multi-compartment 3D bioreactor system

2011 ◽  
Vol 49 (01) ◽  
Author(s):  
SA Hoffmann ◽  
M Lübberstedt ◽  
U Müller-Vieira ◽  
D Knobeloch ◽  
A Nüssler ◽  
...  
Keyword(s):  
Liver Cell ◽  
Human Liver ◽  
In Vitro Toxicity ◽  
Cell Cultivation ◽  
Toxicity Studies ◽  
Human Liver Cell ◽  
Bioreactor System
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