Exploring the role of antigen presenting cells in male genital tract

Andrologia ◽  
2018 ◽  
Vol 50 (11) ◽  
pp. e13120 ◽  
Author(s):  
Vanesa A. Guazzone
Keyword(s):  
Genital Tract ◽  
Antigen Presenting Cells ◽  
Male Genital Tract ◽  
Antigen Presenting ◽  
Male Genital

The role of nuclear medicine in the evaluation of the male genital tract

1993 ◽  
Vol 28 (1) ◽  
pp. 31-42 ◽  
Author(s):  
Chun Ki Kim ◽  
Lionel S. Zuckier ◽  
Abass Alavi
Keyword(s):  
Nuclear Medicine ◽  
Genital Tract ◽  
Male Genital Tract ◽  
Male Genital

Male Genital Tract Inflammation: The Role of Selected Interleukins in Regulation of Pro-Oxidant and Antioxidant Enzymatic Substances in Seminal Plasma

2003 ◽  
Vol 24 (3) ◽  
pp. 448-455 ◽  
Author(s):  
Dorota Sanocka ◽  
Piotr Jędrzejczak ◽  
Anna Szumała-Kaękol ◽  
Monika Frączek ◽  
Maciej Kurpisz
Keyword(s):  
Seminal Plasma ◽  
Genital Tract ◽  
Male Genital Tract ◽  
Male Genital

scholarly journals Age-induced apoptosis in the male genital tract of the mouse

Reproduction ◽  
2004 ◽  
Vol 127 (3) ◽  
pp. 359-366 ◽  
Author(s):  
M Jara ◽  
R Carballada ◽  
P Esponda
Keyword(s):  
Genital Tract ◽  
Caspase 3 ◽  
Ventral Prostate ◽  
Male Genital Tract ◽  
Lipofuscin Granules ◽  
Induction Of Apoptosis ◽  
Induced Apoptosis ◽  
Active Fragment ◽  
Male Genital

We have examined the effects of ageing on the increase in apoptotic cells numbers in the male genital tract of the house mouse (Mus musculus). We have found that not all organs have the same response. There is an induction of apoptosis in both the epididymis and ventral prostate. However, seminal vesicles and other prostatic lobes remain unaffected. Apoptosis was assessed by several methods: TUNEL, detection of the active fragment of caspase-3 and the pattern of DNA fragmentation on agarose gels. This increase in apoptosis is related to the fall in testosterone levels, although there is only a partial decrease in androgen receptor (AR). AR is still present in all tissues and only moderately reduced in the epididymis and ventral prostate. A more intense increase of lipofuscin granules, which may be indicative of oxidative stress, occurred in these tissues. Finally, testosterone supplementation reverses the changes (both in apoptosis and lipofuscin content in the tissue), suggesting a role of androgens in these processes.

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