Serum concentrations of soluble B7-H4 in early pregnancy are elevated in women with preterm premature rupture of fetal membranes

2016 ◽  
Vol 76 (2) ◽  
pp. 149-154 ◽  
Author(s):  
Pawel Mach ◽  
Angela Köninger ◽  
Lukasz Wicherek ◽  
Rainer Kimmig ◽  
Sabine Kasimir-Bauer ◽  
...  
Keyword(s):  
Early Pregnancy ◽  
Fetal Membranes ◽  
Serum Concentrations ◽  
Premature Rupture ◽  
Preterm Premature Rupture

The role of apoptosis in preterm premature rupture of the human fetal membranes

2013 ◽  
Vol 288 (3) ◽  
pp. 501-505 ◽  
Author(s):  
Aylin Saglam ◽  
Cinar Ozgur ◽  
Iris Derwig ◽  
Bekir Serdar Unlu ◽  
Funda Gode ◽  
...  
Keyword(s):  
Fetal Membranes ◽  
Premature Rupture ◽  
Preterm Premature Rupture

Risk factors for preterm premature rupture of fetal membranes: A multicenter case-control study

1990 ◽  
Vol 163 (1) ◽  
pp. 130-137 ◽  
Author(s):  
James H. Harger ◽  
Ann W. Hsing ◽  
Ruth E. Tuomala ◽  
Ronald S. Gibbs ◽  
Philip B. Mead ◽  
...  
Keyword(s):  
Risk Factors ◽  
Case Control Study ◽  
Case Control ◽  
Fetal Membranes ◽  
Premature Rupture ◽  
Preterm Premature Rupture ◽  
Control Study

scholarly journals Ubiquitin-Proteasome-Collagen (CUP) Pathway in Preterm Premature Rupture of Fetal Membranes

2017 ◽  
Vol 8 ◽  
Author(s):  
Xinliang Zhao ◽  
Xiaoyan Dong ◽  
Xiucui Luo ◽  
Jing Pan ◽  
Weina Ju ◽  
...  
Keyword(s):  
Fetal Membranes ◽  
Premature Rupture ◽  
Preterm Premature Rupture ◽  
Ubiquitin Proteasome

A clinical case of pregnancy with suspected trophoblastic disease in 3 trimester

2014 ◽  
Vol 63 (3) ◽  
pp. 66-70
Author(s):  
Yevgeniy Sergeyevich Mikhaylin ◽  
Lada Anatolyevna Ivanova ◽  
Alla Sergeyevna Lisyanskaya ◽  
Aleksey Gennadyevich Savitskiy ◽  
Anna Gennadyevna Minina ◽  
...  
Keyword(s):  
Clinical Case ◽  
Hydatidiform Mole ◽  
Intrauterine Infection ◽  
Fetal Membranes ◽  
Premature Rupture ◽  
Trophoblastic Disease ◽  
Preterm Premature Rupture ◽  
Placental Blood ◽  
Β Hcg ◽  
Placental Blood Flow

Cases of trophoblastic disease in the presence of the living fetus during 2-3 trimesters of pregnancy is a rare phenomenon. The description of the clinical case of suspected trophoblastic disease at term of 26 weeks is provided in article. The decision of pregnancy prolongation under control β- HCG was made. Therapy of gestosis, improvement of maternal-placental blood flow, anticoagulant therapy was carried out. Cesarean section was made at 30 weeks of pregnancy (preterm premature rupture of fetal membranes). In the postpartum period, a decrease of b-HCG to zero was within 1,5 months. In the postoperative period we did not receive convincing pathomorphological data for the presence of trophoblastic disease, so the question of whether there was in this case partial hydatidiform mole in combination with alive fetus, or received changes in the placenta and anomalously high values of b-HCG were the result of primary placental insufficiency with the intrauterine infection, remains open.

The Chorion Layer of Fetal Membranes Is Prematurely Destroyed in Women With Preterm Premature Rupture of the Membranes

2013 ◽  
Vol 20 (10) ◽  
pp. 1246-1254 ◽  
Author(s):  
Bernard J. Canzoneri ◽  
Liping Feng ◽  
Chad A. Grotegut ◽  
Rex C. Bentley ◽  
R. Phillips Heine ◽  
...  
Keyword(s):  
Fetal Membranes ◽  
Premature Rupture ◽  
Preterm Premature Rupture

scholarly journals A mouse model of spontaneous preterm birth based on the genetic ablation of biglycan and decorin

Reproduction ◽  
2011 ◽  
Vol 142 (1) ◽  
pp. 183-194 ◽  
Author(s):  
Megan L Calmus ◽  
Elyse E Macksoud ◽  
Richard Tucker ◽  
Renato V Iozzo ◽  
Beatrice E Lechner
Keyword(s):  
Preterm Birth ◽  
Fetal Membranes ◽  
Dependent Manner ◽  
Null Mutant ◽  
Wild Type ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Ehlers Danlos Syndrome ◽  
Genetic Ablation ◽  
Preterm Premature Rupture

Preterm premature rupture of membranes is responsible for one-third of preterm births. Ehlers–Danlos syndrome (EDS) is associated with preterm premature rupture of membranes in humans. In particular, an EDS variant is caused by a genetic mutation resulting in abnormal secretion of biglycan and decorin, two small leucine-rich proteoglycans highly expressed in reproductive tissues. Because biglycan/decorin null mutant (Bgn−/−Dcn−/−) mice demonstrate phenotypic changes similar to EDS, we used this model to test whether either biglycan or decorin or both play a role in the attainment of successful term gestation. Wild-type biglycan null mutant, decorin null mutant, and biglycan/decorin null mutant pregnancies were assessed for the length of gestation, pup and placenta weight, and litter size. Quantitative real-time PCR was performed to measure biglycan and decorin gene expression, and immunohistochemistry was performed to assess protein expression in placenta and fetal membranes at embryonic days E12, E15, and E18.Bgn−/−Dcn−/−dams displayed preterm birth, whereas the possession of at least two biglycan or decorin wild-type alleles was protective of preterm birth. The number ofBgn−/−Dcn−/−pups was decreased at postnatal day P1 but not at E18. Biglycan and decorin were upregulated in the placenta in the absence of each other and were developmentally regulated in fetal membranes, suggesting that these two proteoglycans demonstrate genetic complementation and contribute to gestational success in a dose-dependent manner. Thus, the biglycan/decorin null mutant mouse is a model of genetically induced preterm birth and perinatal loss. This model presents novel targets for preventive or therapeutic manipulation of preterm birth.

Risk Factors for Preterm Premature Rupture of the Fetal Membranes

1990 ◽  
Vol 7 (04) ◽  
pp. 374-379 ◽  
Author(s):  
Carolyn Hadley ◽  
Denise Main ◽  
Steven Gabbe
Keyword(s):  
Risk Factors ◽  
Fetal Membranes ◽  
Premature Rupture ◽  
Preterm Premature Rupture
Sign in / Sign up

Export Citation Format

Share Document