Active Expectant Management Prolongs Latency in Multiple Gestations Complicated by Preterm Premature Rupture of Fetal Membranes (PROM)

1992 ◽  
Vol 4 (S1) ◽  
pp. 21-25 ◽  
Author(s):  
S. J. Fortunato ◽  
S. I. Welt ◽  
E. C. Bryant ◽  
M. K. Eggleston
Keyword(s):  
Expectant Management ◽  
Fetal Membranes ◽  
Premature Rupture ◽  
Preterm Premature Rupture ◽  
Multiple Gestations

Active Expectant Management of Preterm Premature Rupture of Fetal Membranes (PROM) with Cervical Cerclage

1992 ◽  
Vol 4 (S1) ◽  
pp. 26-30
Author(s):  
S. J. Fortunato ◽  
S. I. Welt ◽  
E. C. Bryant ◽  
M. K. Eggleston
Keyword(s):  
Expectant Management ◽  
Fetal Membranes ◽  
Premature Rupture ◽  
Cervical Cerclage ◽  
Preterm Premature Rupture

scholarly journals Outcomes of prolonged preterm premature rupture of the membrane: a report of six cases

2018 ◽  
Vol 8 (1) ◽  
pp. 329
Author(s):  
Asha Dixit
Keyword(s):  
Maternal Morbidity ◽  
Complete Blood Count ◽  
Clinical Investigation ◽  
Present Report ◽  
Latency Period ◽  
Expectant Management ◽  
Premature Rupture ◽  
Preterm Premature Rupture ◽  
Foetal Mortality ◽  
Litmus Test

Preterm premature rupture of the membranes (PROM) is associated with significant maternal morbidity and perinatal mortality. With an increasing era of infertility, the main interest of an assisted reproductive technology specialist is to increase the take-home baby rate. Here authors present report on the outcomes of prolonged preterm PROM cases facilitated with expectant management. Report is based on the medical records of six women with preterm PROM between 16-31 weeks of gestation who gave their consent to continue the pregnancy. These women were diagnosed with PROM by the litmus test and per speculum examination. Ultrasound scan and clinical investigation, which included complete blood count and C-reactive protein level, were performed in all cases. Prophylactic antibiotics were administered to prevent the infection and increase the latency period. All six babies (100%) were delivered successfully. There was no foetal mortality and maternal morbidity observed. Expectant management in preterm PROM cases can increase the survival rate and hence the take-home baby rate.

scholarly journals Active versus expectant management of preterm premature rupture of membrane before 34 weeks and neonatal outcome

2021 ◽  
Vol 8 (3) ◽  
pp. 501
Author(s):  
Gouda A. P. Kartikeswar ◽  
Dhyey I. Pandya ◽  
Siddharth Madabhushi ◽  
Vivek M. Joshi ◽  
Sandeep Kadam
Keyword(s):  
Gestational Age ◽  
Neonatal Outcome ◽  
Tertiary Care ◽  
Expectant Management ◽  
Active Management ◽  
Respiratory Support ◽  
Care Hospital ◽  
Premature Rupture ◽  
Preterm Premature Rupture ◽  
Significant Difference

Background: Preterm premature rupture of membranes (PPROM) predisposes the mother for chorioamnionitis, endometritis, bacteremia and neonate to preterm delivery related complication. There is often dilemma regarding the management of PPROM in mothers with gestational age (GA) <34 weeks.Methods: A retrospective cohort study conducted in a tertiary care hospital over two year period. Neonates delivered before 34 weeks were enrolled and categorized into active management (AM) and expectant management (EM) group. Associated risk factors, duration of PPROM and latency period, Neonatal outcomes like sepsis, morbidity, duration of respiratory support, duration of NICU stay compared between groups.Results: Out of total 197 cases, AM group had 91 babies. Active management resulted in earlier delivery [mean GA (SD): 30.88(1.8) VS 31(2.1) weeks], higher number of caesarian section (76.9% versus 53.8%), lesser birth weight {1233.6 (±282.9) versus 1453.39 (±380.6) gm} and more ELBW babies (23.1% versus 7.5%). EM resulted in significantly higher antenatal steroid cover (73.6% in AM versus 89.6% in EM) and lesser need of surfactant for RDS [42.9% versus 28.3%]. Significant difference was found for NICU stay days {mean (SD): 25.46 (16.8) versus 20.94 (17.5)}. No difference found between respiratory support days [median (IQR) 2 (0, 6) versus 2 (0, 7)]. No significant differences found in incidence of maternal chorioamnionitis, NEC, sepsis, BPD and ROP. Early delivery resulted in higher mortality though that was statistically not significant.Conclusions: Gestational age at delivery is more important predictor of neonatal outcome then PPROM in early preterm. 

scholarly journals Active Versus Expectant Management for Preterm Premature Rupture of Membranes at 34–36 Weeks of Gestation and the Associated Adverse Perinatal Outcomes

2020 ◽  
Vol 42 (11) ◽  
pp. 717-725
Author(s):  
Malú Flôres Ferraz ◽  
Thaísa De Souza Lima ◽  
Sarah Moura Cintra ◽  
Edward Araujo Júnior ◽  
Caetano Galvão Petrini ◽  
...  
Keyword(s):  
Gestational Age ◽  
Perinatal Outcomes ◽  
Expectant Management ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Preterm Premature Rupture ◽  
Management Group ◽  
Group I ◽  
Adverse Perinatal Outcomes ◽  
Group Ii

Abstract Objective To compare the type of management (active versus expectant) for preterm premature rupture of membranes (PPROM) between 34 and 36 + 6 weeks of gestation and the associated adverse perinatal outcomes in 2 tertiary hospitals in the southeast of Brazil. Methods In the present retrospective cohort study, data were obtained by reviewing the medical records of patients admitted to two tertiary centers with different protocols for PPROM management. The participants were divided into two groups based on PPROM management: group I (active) and group II (expectant). For statistical analysis, the Student t-test, the chi-squared test, and binary logistic regression were used. Results Of the 118 participants included, 78 underwent active (group I) and 40 expectant management (group II). Compared with group II, group I had significantly lower mean amniotic fluid index (5.5 versus 11.3 cm, p = 0.002), polymerase chain reaction at admission (1.5 versus 5.2 mg/dl, p = 0.002), time of prophylactic antibiotics (5.4 versus 18.4 hours, p < 0.001), latency time (20.9 versus 33.6 hours, p = 0.001), and gestational age at delivery (36.5 versus 37.2 weeks, p = 0.025). There were no significant associations between the groups and the presence of adverse perinatal outcomes. Gestational age at diagnosis was the only significant predictor of adverse composite outcome (x2 [1] = 3.1, p = 0.0001, R2 Nagelkerke = 0.138). Conclusion There was no association between active versus expectant management in pregnant women with PPROM between 34 and 36 + 6 weeks of gestation and adverse perinatal outcomes.

The role of apoptosis in preterm premature rupture of the human fetal membranes

2013 ◽  
Vol 288 (3) ◽  
pp. 501-505 ◽  
Author(s):  
Aylin Saglam ◽  
Cinar Ozgur ◽  
Iris Derwig ◽  
Bekir Serdar Unlu ◽  
Funda Gode ◽  
...  
Keyword(s):  
Fetal Membranes ◽  
Premature Rupture ◽  
Preterm Premature Rupture

Risk factors for preterm premature rupture of fetal membranes: A multicenter case-control study

1990 ◽  
Vol 163 (1) ◽  
pp. 130-137 ◽  
Author(s):  
James H. Harger ◽  
Ann W. Hsing ◽  
Ruth E. Tuomala ◽  
Ronald S. Gibbs ◽  
Philip B. Mead ◽  
...  
Keyword(s):  
Risk Factors ◽  
Case Control Study ◽  
Case Control ◽  
Fetal Membranes ◽  
Premature Rupture ◽  
Preterm Premature Rupture ◽  
Control Study

scholarly journals Ubiquitin-Proteasome-Collagen (CUP) Pathway in Preterm Premature Rupture of Fetal Membranes

2017 ◽  
Vol 8 ◽  
Author(s):  
Xinliang Zhao ◽  
Xiaoyan Dong ◽  
Xiucui Luo ◽  
Jing Pan ◽  
Weina Ju ◽  
...  
Keyword(s):  
Fetal Membranes ◽  
Premature Rupture ◽  
Preterm Premature Rupture ◽  
Ubiquitin Proteasome

A clinical case of pregnancy with suspected trophoblastic disease in 3 trimester

2014 ◽  
Vol 63 (3) ◽  
pp. 66-70
Author(s):  
Yevgeniy Sergeyevich Mikhaylin ◽  
Lada Anatolyevna Ivanova ◽  
Alla Sergeyevna Lisyanskaya ◽  
Aleksey Gennadyevich Savitskiy ◽  
Anna Gennadyevna Minina ◽  
...  
Keyword(s):  
Clinical Case ◽  
Hydatidiform Mole ◽  
Intrauterine Infection ◽  
Fetal Membranes ◽  
Premature Rupture ◽  
Trophoblastic Disease ◽  
Preterm Premature Rupture ◽  
Placental Blood ◽  
Β Hcg ◽  
Placental Blood Flow

Cases of trophoblastic disease in the presence of the living fetus during 2-3 trimesters of pregnancy is a rare phenomenon. The description of the clinical case of suspected trophoblastic disease at term of 26 weeks is provided in article. The decision of pregnancy prolongation under control β- HCG was made. Therapy of gestosis, improvement of maternal-placental blood flow, anticoagulant therapy was carried out. Cesarean section was made at 30 weeks of pregnancy (preterm premature rupture of fetal membranes). In the postpartum period, a decrease of b-HCG to zero was within 1,5 months. In the postoperative period we did not receive convincing pathomorphological data for the presence of trophoblastic disease, so the question of whether there was in this case partial hydatidiform mole in combination with alive fetus, or received changes in the placenta and anomalously high values of b-HCG were the result of primary placental insufficiency with the intrauterine infection, remains open.

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