scholarly journals Detection of Imprinting Effects for Quantitative Traits on X Chromosome Using Nuclear Families with Multiple Daughters

2017 ◽  
Vol 81 (4) ◽  
pp. 147-160 ◽  
Author(s):  
Kexin Yu ◽  
Ji-Yuan Zhou ◽  
Wing Kam Fung
Keyword(s):  
X Chromosome ◽  
Quantitative Traits ◽  
Nuclear Families

scholarly journals Hybrid dysgenesis-induced quantitative variation on the X chromosome of Drosophila melanogaster.

Genetics ◽  
1990 ◽  
Vol 124 (3) ◽  
pp. 627-636
Author(s):  
C Q Lai ◽  
T F Mackay
Keyword(s):  
Drosophila Melanogaster ◽  
X Chromosome ◽  
Quantitative Traits ◽  
Natural Populations ◽  
Quantitative Variation ◽  
Hybrid Dysgenesis ◽  
X Chromosomes ◽  
Bristle Number ◽  
Seven Generations ◽  
Polygenic Variation

Abstract To determine the ability of the P-M hybrid dysgenesis system of Drosophila melanogaster to generate mutations affecting quantitative traits, X chromosome lines were constructed in which replicates of isogenic M and P strain X chromosomes were exposed to a dysgenic cross, a nondysgenic cross, or a control cross, and recovered in common autosomal backgrounds. Mutational heritabilities of abdominal and sternopleural bristle score were in general exceptionally high-of the same magnitude as heritabilities of these traits in natural populations. P strain chromosomes were eight times more mutable than M strain chromosomes, and dysgenic crosses three times more effective than nondysgenic crosses in inducing polygenic variation. However, mutational heritabilities of the bristle traits were appreciable for P strain chromosomes passed through one nondysgenic cross, and for M strain chromosomes backcrossed for seven generations to inbred P strain females, a result consistent with previous observations on mutations affecting quantitative traits arising from nondysgenic crosses. The new variation resulting from one generation of mutagenesis was caused by a few lines with large effects on bristle score, and all mutations reduced bristle number.

scholarly journals Detection of Parent-of-Origin Effects for Quantitative Traits in Complete and Incomplete Nuclear Families With Multiple Children

2011 ◽  
Vol 174 (2) ◽  
pp. 226-233 ◽  
Author(s):  
Feng He ◽  
Ji-Yuan Zhou ◽  
Yue-Qing Hu ◽  
Fengzhu Sun ◽  
Jingyuan Yang ◽  
...  
Keyword(s):  
Quantitative Traits ◽  
Nuclear Families ◽  
Parent Of Origin ◽  
Origin Effects

scholarly journals Familial aggregation and heritability of asthma-associated quantitative traits in a population-based sample of nuclear families

2000 ◽  
Vol 8 (11) ◽  
pp. 853-860 ◽  
Author(s):  
Lyle J Palmer ◽  
Paul R Burton ◽  
Alan L James ◽  
A William Musk ◽  
William OCM Cookson
Keyword(s):  
Quantitative Traits ◽  
Familial Aggregation ◽  
Population Based ◽  
Nuclear Families

scholarly journals Detecting Rare Variants for Quantitative Traits Using Nuclear Families

2012 ◽  
Vol 73 (3) ◽  
pp. 148-158 ◽  
Author(s):  
Wei Guo ◽  
Yin Yao Shugart
Keyword(s):  
Quantitative Traits ◽  
Rare Variants ◽  
Nuclear Families

scholarly journals A General Test of Association for Quantitative Traits in Nuclear Families

2000 ◽  
Vol 66 (1) ◽  
pp. 279-292 ◽  
Author(s):  
G.R. Abecasis ◽  
L.R. Cardon ◽  
W.O.C. Cookson
Keyword(s):  
Quantitative Traits ◽  
Nuclear Families ◽  
General Test

Gibbs sampling-based segregation analysis of asthma-associated quantitative traits in a population-based sample of nuclear families

2001 ◽  
Vol 20 (3) ◽  
pp. 356-372 ◽  
Author(s):  
Lyle J. Palmer ◽  
William O.C.M. Cookson ◽  
Alan L. James ◽  
A. William Musk ◽  
Paul R. Burton
Keyword(s):  
Gibbs Sampling ◽  
Quantitative Traits ◽  
Segregation Analysis ◽  
Population Based ◽  
Nuclear Families

Segregation analysis of quantitative traits in nuclear families: Comparison of three program packages

1989 ◽  
Vol 6 (6) ◽  
pp. 713-726 ◽  
Author(s):  
Lyle W. Konigsberg ◽  
Candace M. Kammerer ◽  
Jean W. MacCluer ◽  
D. C. Rao ◽  
G. P. Vogler
Keyword(s):  
Quantitative Traits ◽  
Segregation Analysis ◽  
Nuclear Families

scholarly journals Flexible and Robust Methods for Rare-Variant Testing of Quantitative Traits in Trios and Nuclear Families

2014 ◽  
Vol 38 (6) ◽  
pp. 542-551 ◽  
Author(s):  
Yunxuan Jiang ◽  
Karen N. Conneely ◽  
Michael P. Epstein
Keyword(s):  
Rare Variant ◽  
Quantitative Traits ◽  
Robust Methods ◽  
Nuclear Families
Sign in / Sign up

Export Citation Format

Share Document