Curved-Array-Based Multispectral Photoacoustic Imaging of Human Finger Joints

2018 ◽  
Vol 65 (7) ◽  
pp. 1452-1459 ◽  
Author(s):  
Na Huang ◽  
Ming He ◽  
Haosheng Shi ◽  
Yuan Zhao ◽  
Man Lu ◽  
...  
Sensors ◽  
2019 ◽  
Vol 19 (22) ◽  
pp. 4861 ◽  
Author(s):  
Sumit Agrawal ◽  
Christopher Fadden ◽  
Ajay Dangi ◽  
Xinyi Yang ◽  
Hussain Albahrani ◽  
...  

Photoacoustic computed tomography (PACT) has been widely explored for non-ionizing functional and molecular imaging of humans and small animals. In order for light to penetrate deep inside tissue, a bulky and high-cost tunable laser is typically used. Light-emitting diodes (LEDs) have recently emerged as cost-effective and portable alternative illumination sources for photoacoustic imaging. In this study, we have developed a portable, low-cost, five-dimensional (x, y, z, t, λ ) PACT system using multi-wavelength LED excitation to enable similar functional and molecular imaging capabilities as standard tunable lasers. Four LED arrays and a linear ultrasound transducer detector array are housed in a hollow cylindrical geometry that rotates 360 degrees to allow multiple projections through the subject of interest placed inside the cylinder. The structural, functional, and molecular imaging capabilities of the LED–PACT system are validated using various tissue-mimicking phantom studies. The axial, lateral, and elevational resolutions of the system at 2.3 cm depth are estimated as 0.12 mm, 0.3 mm, and 2.1 mm, respectively. Spectrally unmixed photoacoustic contrasts from tubes filled with oxy- and deoxy-hemoglobin, indocyanine green, methylene blue, and melanin molecules demonstrate the multispectral molecular imaging capabilities of the system. Human-finger-mimicking phantoms made of a bone and blood tubes show structural and functional oxygen saturation imaging capabilities. Together, these results demonstrate the potential of the proposed LED-based, low-cost, portable PACT system for pre-clinical and clinical applications.


2006 ◽  
Author(s):  
Alexander D. Klose ◽  
Rong Song ◽  
Alexander K. Scheel ◽  
Uwe Netz ◽  
Jürgen Beuthan ◽  
...  

We address two related aspects of NMR chemical microscopy of intact mammalian tissues: attainment of high spatial resolution images; and incorporation of a level of chemical discrimination by sensitizing the image intensity of either chemical shift or nuclear relaxation. These concepts are illustrated with images of human finger joints and of the head or heart of rat.


2019 ◽  
Vol 46 (5) ◽  
pp. 2363-2369 ◽  
Author(s):  
Zihui Chi ◽  
Lin Huang ◽  
Shaoli Ge ◽  
Huabei Jiang

2021 ◽  
Vol 8 (6) ◽  
pp. 974-978
Author(s):  
Samara Munaem Naeem ◽  
Majid H. Faidh-Allah

The most important function of a prosthetic hand is their ability to perform tasks in a manner similar to a natural hand, so it is necessary to perform kinematic analysis to determine the performance and the ability of the prosthetic human finger design to work normally and smoothly when it's drive by two sets of links that embedded in its structure and pulled by a servomotor, so the Denvit-Hartenberg method was used to analyse the forward kinematics for the prosthetic finger joints to deduction the trajectory of the fingertip and the velocity of the joints was computed by using the Jacobian matrix. The prosthetic finger was modelled by the Solidwork - 2018 program and the results of kinematics were verified using MATLAB. The analyses that were conducted on the design showed that the designed prosthetic finger has the ability to perform movements and meets the functional requirements for which it is designed.


2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Yubin Liu ◽  
Yating Wang ◽  
Zhen Yuan

We developed a homemade dual-modality imaging system that combines multispectral photoacoustic computed tomography and ultrasound computed tomography for reconstructing the structural and functional information of human finger joint systems. The fused multispectral photoacoustic-ultrasound computed tomography (MPAUCT) system was examined by the phantom andin vivoexperimental tests. The imaging results indicate that the hard tissues such as the bones and the soft tissues including the blood vessels, the tendon, the skins, and the subcutaneous tissues in the finger joints systems can be effectively recovered by using our multimodality MPAUCT system. The developed MPAUCT system is able to provide us with more comprehensive information of the human finger joints, which shows its potential for characterization and diagnosis of bone or joint diseases.


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