A survey of some applications of NMR chemical microscopy

We address two related aspects of NMR chemical microscopy of intact mammalian tissues: attainment of high spatial resolution images; and incorporation of a level of chemical discrimination by sensitizing the image intensity of either chemical shift or nuclear relaxation. These concepts are illustrated with images of human finger joints and of the head or heart of rat.

2011 ◽  
Vol 211 (1) ◽  
pp. 80-88
Author(s):  
Rudolf Fritz Fischer ◽  
Christof Baltes ◽  
Kilian Weiss ◽  
Aju Pazhenkottil ◽  
Markus Rudin ◽  
...  

2015 ◽  
Vol 1 (1) ◽  
Author(s):  
Huang Lin ◽  
Qi Weizhi ◽  
Zhao Yuan ◽  
Chi Zihui ◽  
Zhang Nengzhu ◽  
...  

AbstractIn this study, we explore a new application of thermoacoustic tomography (TAT) for imaging human finger joints and bones. Three volunteers’ finger joints and bones were visualized with satisfying image contrast and spatial resolution by a TAT scanner. The recovered TAT images revealed apparent microwave absorption differences between the joint cavity and bone. Beyond the full single finger imaging, a volunteer’s four fingers were clearly and concurrently imaged. To confirm our observations, MRI images of two volunteers’ fingers were performed, and the TAT recovered shape/size of the fingers were consistent with the MRI findings. To further assess the feasibility of TAT for finger joint and bone imaging, we quantitatively calculated the conductivity of a case. This initial study suggests that TAT may be a good candidate for screening, diagnosing, and monitoring treatment of joint and bone diseases.


Author(s):  
Caprice Gray ◽  
Daniel Apone ◽  
Chris Rogers ◽  
Vincent P. Manno ◽  
Chris Barns ◽  
...  

Modifications to the Dual Emission Laser Induced Fluorescence (DELIF) procedure used to collect images of the slurry layer between the polishing pad and wafer during Chemical Mechanical Planarization (CMP) have provided a means to attain instantaneous, high spatial resolution images of slurry film thickness. Presented here is a technique to determine the calibration factor that correlates image intensity to slurry film thickness. This presentation will discuss how to determine slurry layer shape near wafer features, pad roughness, and pad compressibility.


Author(s):  
K. Przybylski ◽  
A. J. Garratt-Reed ◽  
G. J. Yurek

The addition of so-called “reactive” elements such as yttrium to alloys is known to enhance the protective nature of Cr2O3 or Al2O3 scales. However, the mechanism by which this enhancement is achieved remains unclear. An A.E.M. study has been performed of scales grown at 1000°C for 25 hr. in pure O2 on Co-45%Cr implanted at 70 keV with 2x1016 atoms/cm2 of yttrium. In the unoxidized alloys it was calculated that the maximum concentration of Y was 13.9 wt% at a depth of about 17 nm. SIMS results showed that in the scale the yttrium remained near the outer surface.


Author(s):  
E. G. Rightor

Core edge spectroscopy methods are versatile tools for investigating a wide variety of materials. They can be used to probe the electronic states of materials in bulk solids, on surfaces, or in the gas phase. This family of methods involves promoting an inner shell (core) electron to an excited state and recording either the primary excitation or secondary decay of the excited state. The techniques are complimentary and have different strengths and limitations for studying challenging aspects of materials. The need to identify components in polymers or polymer blends at high spatial resolution has driven development, application, and integration of results from several of these methods.


Author(s):  
Kosuke Nomura ◽  
Ryutaro Oi ◽  
Takanori Senoh ◽  
Taiichiro Kurita ◽  
Takayuki Hamamoto

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