Industrial crystallization process control

doi:10.1109/mcs.2006.1657878

Industrial crystallization process control

IEEE Control Systems Magazine ◽

10.1109/mcs.2006.1657878 ◽

2006 ◽

Vol 26 (4) ◽

pp. 70-80 ◽

Cited By ~ 65

Keyword(s):

Process Control ◽

Crystallization Process ◽

Industrial Crystallization

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NMPC of an industrial crystallization process using model-based observers

Journal of Industrial and Engineering Chemistry ◽

10.1016/j.jiec.2010.07.014 ◽

2010 ◽

Vol 16 (5) ◽

pp. 708-716 ◽

Cited By ~ 26

Author(s):

Cédric Damour ◽

Michel Benne ◽

Lionel Boillereaux ◽

Brigitte Grondin-Perez ◽

Jean-Pierre Chabriat

Keyword(s):

Crystallization Process ◽

Industrial Crystallization ◽

Model Based

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Application of Ultrasound Measurements as PAT Tools for Industrial Crystallization Process Development of Pharmaceutical Compounds

Organic Process Research & Development ◽

10.1021/op4001803 ◽

2013 ◽

Vol 19 (1) ◽

pp. 110-121 ◽

Cited By ~ 7

Author(s):

Lydia Helmdach ◽

Martin P. Feth ◽

Joachim Ulrich

Keyword(s):

Crystallization Process ◽

Process Development ◽

Pharmaceutical Compounds ◽

Industrial Crystallization ◽

Ultrasound Measurements

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SIMULATION AND NEW SENSOR TECHNOLOGIES FOR INDUSTRIAL CRYSTALLIZATION: A REVIEW

International Journal of Modern Physics B ◽

10.1142/s0217979202009858 ◽

2002 ◽

Vol 16 (01n02) ◽

pp. 346-353 ◽

Cited By ~ 18

Author(s):

RICHARD D. BRAATZ ◽

MITSUKO FUJIWARA ◽

DAVID L. MA ◽

TIMOKLEIA TOGKALIDOU ◽

DANESH K. TAFTI

Keyword(s):

High Resolution ◽

Size Distribution ◽

Crystal Size ◽

Crystallization Process ◽

Significant Proportion ◽

Nucleation And Growth ◽

Crystalline Form ◽

Industrial Crystallization ◽

Growth From Solution ◽

Product Effectiveness

A significant proportion of materials are produced in crystalline form. Many of these crystals are produced by nucleation and growth from solution. In these processes, the control of the crystal size distribution can be critically important for efficient downstream operations such as filtration and drying, and product effectiveness (e.g., flowability, bioavailability, tablet stability). Such control has recently become possible due to new sensor technologies that can peer into the crystallization process as it occurs, and high resolution algorithms which can efficiently simulate crystallization processes. This paper provides an overview of recent advances in areas.

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