Sequence-pair based placement with boundary constraints

2003 ◽  
Author(s):  
Chih-Hung Lee ◽  
Yi-Lin Hsieh ◽  
Hui-Chun Lee ◽  
Tsai-Ming Hsieh
Keyword(s):  
Sequence Pair ◽  
Boundary Constraints

DEFOGGING OF IMAGE USING SPATIAL MRF WITH BOUNDARY CONSTRAINTS

2019 ◽  
Vol 6 (2) ◽  
pp. 28
Author(s):  
DORA H. SIVACHANUKYA ◽  
PRAKASH M. SUNIL ◽  
◽  
Keyword(s):  
Boundary Constraints

Research on Perfect Ternary Sequence Pair

2011 ◽  
Vol 30 (11) ◽  
pp. 2622-2625
Author(s):  
Fei Mao ◽  
Ning Wu ◽  
Zheng Zhou
Keyword(s):  
Sequence Pair

scholarly journals Surface-directed engineering of tissue anisotropy in microphysiological models of musculoskeletal tissue

2021 ◽  
Vol 7 (11) ◽  
pp. eabe9446 ◽  
Author(s):  
Mark J. Mondrinos ◽  
Farid Alisafaei ◽  
Alex Y. Yi ◽  
Hossein Ahmadzadeh ◽  
Insu Lee ◽  
...  
Keyword(s):  
Muscle Injury ◽  
Cancer Cachexia ◽  
Myogenic Differentiation ◽  
Mechanical Anisotropy ◽  
Musculoskeletal Tissue ◽  
Boundary Constraints ◽  
Cell Contractility ◽  
Engineered Tissue ◽  
Tissue Anisotropy

Here, we present an approach to model and adapt the mechanical regulation of morphogenesis that uses contractile cells as sculptors of engineered tissue anisotropy in vitro. Our method uses heterobifunctional cross-linkers to create mechanical boundary constraints that guide surface-directed sculpting of cell-laden extracellular matrix hydrogel constructs. Using this approach, we engineered linearly aligned tissues with structural and mechanical anisotropy. A multiscale in silico model of the sculpting process was developed to reveal that cell contractility increases as a function of principal stress polarization in anisotropic tissues. We also show that the anisotropic biophysical microenvironment of linearly aligned tissues potentiates soluble factor-mediated tenogenic and myogenic differentiation of mesenchymal stem cells. The application of our method is demonstrated by (i) skeletal muscle arrays to screen therapeutic modulators of acute oxidative injury and (ii) a 3D microphysiological model of lung cancer cachexia to study inflammatory and oxidative muscle injury induced by tumor-derived signals.

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