scholarly journals Time delay-accelerated transition of gene switch and -enhanced stochastic resonance in a bistable gene regulatory model

Author(s):  
Canjun Wang ◽  
Ming Yi ◽  
Keli Yang
2019 ◽  
Vol 12 (06) ◽  
pp. 1950067 ◽  
Author(s):  
Zhaohua Wu ◽  
Zhiming Wang ◽  
Tiejun Zhou

Fractional-order gene regulatory networks with time delay (DFGRNs) have proven that they are more suitable to model gene regulation mechanism than integer-order. In this paper, a novel DFGRN is proposed. The existence and uniqueness of the equilibrium point for the DFGRN are proved under certain conditions. On this basis, the conditions on the global asymptotic stability are established by using the Lyapunov method and comparison theorem for the DFGRN, and the stability conditions are dependent on the fractional-order [Formula: see text]. Finally, numerical simulations show that the obtained results are reasonable.


2021 ◽  
Author(s):  
Qiubao Wang ◽  
Hao Wu ◽  
Yuejuan Yang

Abstract This paper proposes the stiffness nonlinearities and asymmetric SD (smooth and discontinuous) oscillators under time-delay feedback control with a fractional damping. With the effect of displacement and velocity feedback, the oscillator is adjusted to the desired vibration state and then the stochastic resonance (SR) is achieved. This article discusses the contribution of various system parameters and time-delay feedback to SR, especially which induced by fractional damping. It should be noted that this paper provides effective guidance for fault diagnosis and weak signal detection, energy harvesting, vibration isolation and vibration reduction.


2019 ◽  
Vol 33 (28) ◽  
pp. 1950341 ◽  
Author(s):  
Lifang He ◽  
Dayun Hu ◽  
Gang Zhang ◽  
Siliang Lu

The asymmetric bistable system with time delays in the feedback force and random force under multiplicative and additive Gaussian noise is studied. Using the small time delay approximation approach and time-delayed Fokker–Planck equations (FPE), the signal-to-noise ratio (SNR) of the proposed stochastic system is obtained. The stochastic resonance (SR) phenomena influenced by parameters — including system parameters [Formula: see text], [Formula: see text], asymmetry parameter [Formula: see text], time delay [Formula: see text], strength [Formula: see text] of the time-delayed feedback, noise intensities [Formula: see text] and [Formula: see text] of multiplicative and additive noise, and correlation strength [Formula: see text] between two noises, are also analyzed by numerical simulations. Results demonstrate that the SR performance of the asymmetric bistable system is superior to one symmetric bistable system. Besides, both time delay and strength of time-delayed feedback could enhance the SR to some extent. Then, the asymmetric time-delayed bistable SR (ATDBSR) method is used to the bearing fault diagnosis. The engineering applications of the ATDBSR method are realized and the value of the method is verified by effective experimental results.


2015 ◽  
Vol 29 (1-3) ◽  
pp. 346-358 ◽  
Author(s):  
Haitao Yu ◽  
Xinmeng Guo ◽  
Jiang Wang ◽  
Chen Liu ◽  
Bin Deng ◽  
...  

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