An evanescent wave biosensor. II. Fluorescent signal acquisition from tapered fiber optic probes

1994 ◽  
Vol 41 (6) ◽  
pp. 585-591 ◽  
Author(s):  
J.P. Golden ◽  
G.P. Anderson ◽  
S.Y. Rabbany ◽  
F.S. Ligler
2003 ◽  
Author(s):  
Huijie Huang ◽  
Junhui Zhai ◽  
Yongkai Zhao ◽  
Ruifu Yang ◽  
Bingqiang Ren ◽  
...  

Biosensors ◽  
2015 ◽  
Vol 5 (2) ◽  
pp. 158-171 ◽  
Author(s):  
John Miller ◽  
Angelica Castaneda ◽  
Kun Lee ◽  
Martin Sanchez ◽  
Adrian Ortiz ◽  
...  

2001 ◽  
Author(s):  
Ilko K. Ilev ◽  
Ronald W. Waynant ◽  
Michael A. Bonaguidi

1996 ◽  
Vol 68 (17) ◽  
pp. 2905-2912 ◽  
Author(s):  
Andreas P. Abel ◽  
Michael G. Weller ◽  
Gert L. Duveneck ◽  
Markus Ehrat ◽  
H. Michael Widmer

2006 ◽  
Vol 321-323 ◽  
pp. 1168-1171 ◽  
Author(s):  
Gi Young Kim ◽  
Mark T. Morgan ◽  
Daniel Ess ◽  
Byoung Kwon Hahm ◽  
Aparna Kothapalli ◽  
...  

Fiber-optic biosensor uses light transmittable tapered fiber to send excitation laser light and receive emitted fluorescent light. The fluorescent light excited by an evanescent wave generated by the laser is quantitatively related to biomolecules immobilized on the fiber surface [1]. An automated fiber-optic biosensor based detection method for Listeria monocytogenes was developed in this research. Detections of Listeria monocytogenes in hotdog sample were performed to evaluate the method. By using the detection method with automated fiber-optic biosensor, 5.4×107 cfu/ml of Listeria monocytogenes was able to detect.


1991 ◽  
Author(s):  
Gert L. Duveneck ◽  
Markus Ehrat ◽  
H. M. Widmer

1998 ◽  
Vol 79 (01) ◽  
pp. 94-98 ◽  
Author(s):  
Chris Rowe ◽  
Jeni Bolitho ◽  
Andrew Jane ◽  
Peter Bundesen ◽  
Dennis Rylatt ◽  
...  

SummaryWe describe a rapid and sensitive method for detection and quantification of D-dimer and other crosslinked fibrin degradation products (XL-FDPs), which are present in elevated concentrations in patients with sepsis and thrombotic disorders. The method utilizes a sandwich fluoroimmunoassay immobilized in the sensing region of an evanescent wave biosensor. Physiological concentrations of D-dimer and high molecular weight XL-FDP could be determined in buffer and plasma samples on calibrated fibers in 11 min. Samples from septic patients were assayed using ELISA and the fiber optic method; concentrations determined by fiber optic assay were strongly correlated with those determined by ELISA (r = 0.918); intra- and inter-assay errors were comparable to those from ELISAs. Given its accuracy and rapid response time, this fiber optic biosensor shows great potential for development as a diagnostic tool.


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