An evanescent wave biosensor. I. Fluorescent signal acquisition from step-etched fiber optic probes

1994 ◽  
Vol 41 (6) ◽  
pp. 578-584 ◽  
Author(s):  
G.P. Anderson ◽  
J.P. Golden ◽  
F.S. Ligler
Keyword(s):  
Evanescent Wave ◽  
Fiber Optic ◽  
Signal Acquisition ◽  
Fluorescent Signal ◽  
Fiber Optic Probes ◽  
Evanescent Wave Biosensor

Design and application of fiber optic evanescent wave biosensor

2003 ◽  
Author(s):  
Huijie Huang ◽  
Junhui Zhai ◽  
Yongkai Zhao ◽  
Ruifu Yang ◽  
Bingqiang Ren ◽  
...  
Keyword(s):  
Evanescent Wave ◽  
Fiber Optic ◽  
Evanescent Wave Biosensor ◽  
Design And Application

Evanescent-wave delivery into a precise tissue area using fiber optic probes

2001 ◽  
Author(s):  
Ilko K. Ilev ◽  
Ronald W. Waynant ◽  
Michael A. Bonaguidi
Keyword(s):  
Evanescent Wave ◽  
Fiber Optic ◽  
Fiber Optic Probes ◽  
Tissue Area

Fiber-Optic Evanescent Wave Biosensor for the Detection of Oligonucleotides

1996 ◽  
Vol 68 (17) ◽  
pp. 2905-2912 ◽  
Author(s):  
Andreas P. Abel ◽  
Michael G. Weller ◽  
Gert L. Duveneck ◽  
Markus Ehrat ◽  
H. Michael Widmer
Keyword(s):  
Evanescent Wave ◽  
Fiber Optic ◽  
Evanescent Wave Biosensor

Fiber optic evanescent wave biosensor

1991 ◽  
Author(s):  
Gert L. Duveneck ◽  
Markus Ehrat ◽  
H. M. Widmer
Keyword(s):  
Evanescent Wave ◽  
Fiber Optic ◽  
Evanescent Wave Biosensor

Rapid Detection of D-dimer Using a Fiber Optic Biosensor

1998 ◽  
Vol 79 (01) ◽  
pp. 94-98 ◽  
Author(s):  
Chris Rowe ◽  
Jeni Bolitho ◽  
Andrew Jane ◽  
Peter Bundesen ◽  
Dennis Rylatt ◽  
...  
Keyword(s):  
Evanescent Wave ◽  
Rapid Detection ◽  
Fiber Optic ◽  
Degradation Products ◽  
Strongly Correlated ◽  
Plasma Samples ◽  
Fibrin Degradation Products ◽  
Evanescent Wave Biosensor ◽  
D Dimer ◽  
Sensitive Method

SummaryWe describe a rapid and sensitive method for detection and quantification of D-dimer and other crosslinked fibrin degradation products (XL-FDPs), which are present in elevated concentrations in patients with sepsis and thrombotic disorders. The method utilizes a sandwich fluoroimmunoassay immobilized in the sensing region of an evanescent wave biosensor. Physiological concentrations of D-dimer and high molecular weight XL-FDP could be determined in buffer and plasma samples on calibrated fibers in 11 min. Samples from septic patients were assayed using ELISA and the fiber optic method; concentrations determined by fiber optic assay were strongly correlated with those determined by ELISA (r = 0.918); intra- and inter-assay errors were comparable to those from ELISAs. Given its accuracy and rapid response time, this fiber optic biosensor shows great potential for development as a diagnostic tool.

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