Droplet Generation in Standing-Surface-Acoustic-Wave Nebulization at Controlled Air Humidity

2020 ◽  
Vol 14 (1) ◽  
Author(s):  
Mehrzad Roudini ◽  
Dennis Niedermeier ◽  
Frank Stratmann ◽  
Andreas Winkler
Keyword(s):  
Acoustic Wave ◽  
Surface Acoustic Wave ◽  
Droplet Generation ◽  
Air Humidity ◽  
Surface Acoustic Wave Nebulization

scholarly journals Surface acoustic wave nebulization improves compound selectivity of low-temperature plasma ionization for mass spectrometry

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Andreas Kiontke ◽  
Mehrzad Roudini ◽  
Susan Billig ◽  
Amarghan Fakhfouri ◽  
Andreas Winkler ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Low Temperature ◽  
Acoustic Wave ◽  
Surface Acoustic Wave ◽  
Ionization Mechanism ◽  
Low Temperature Plasma ◽  
Ambient Conditions ◽  
Temperature Plasma ◽  
Plasma Ionization ◽  
Surface Acoustic Wave Nebulization

AbstractMass spectrometry coupled to low-temperature plasma ionization (LTPI) allows for immediate and easy analysis of compounds from the surface of a sample at ambient conditions. The efficiency of this process, however, strongly depends on the successful desorption of the analyte from the surface to the gas phase. Whilst conventional sample heating can improve analyte desorption, heating is not desirable with respect to the stability of thermally labile analytes. In this study using aromatic amines as model compounds, we demonstrate that (1) surface acoustic wave nebulization (SAWN) can significantly improve compound desorption for LTPI without heating the sample. Furthermore, (2) SAWN-assisted LTPI shows a response enhancement up to a factor of 8 for polar compounds such as aminophenols and phenylenediamines suggesting a paradigm shift in the ionization mechanism. Additional assets of the new technique demonstrated here are (3) a reduced analyte selectivity (the interquartile range of the response decreased by a factor of 7)—a significant benefit in non-targeted analysis of complex samples—and (4) the possibility for automated online monitoring using an autosampler. Finally, (5) the small size of the microfluidic SAWN-chip enables the implementation of the method into miniaturized, mobile LTPI probes.

scholarly journals Author Correction: Surface acoustic wave nebulization improves compound selectivity of low-temperature plasma ionization for mass spectrometry

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Andreas Kiontke ◽  
Mehrzad Roudini ◽  
Susan Billig ◽  
Armaghan Fakhfouri ◽  
Andreas Winkler ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Low Temperature ◽  
Acoustic Wave ◽  
Surface Acoustic Wave ◽  
Low Temperature Plasma ◽  
Temperature Plasma ◽  
Plasma Ionization ◽  
Surface Acoustic Wave Nebulization

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

scholarly journals Self-Aligned Interdigitated Transducers for Acoustofluidics

2016 ◽  
Author(s):  
Zhichao Ma ◽  
Adrian J. T. Teo ◽  
Say Hwa Tan ◽  
Ye Ai ◽  
Nam-Trung Nguyen
Keyword(s):  
Acoustic Wave ◽  
Surface Acoustic Wave ◽  
Particle Separation ◽  
Microfluidic Devices ◽  
Current Approach ◽  
Droplet Generation ◽  
Microfluidic Channels ◽  
Clean Room ◽  
Precise Location ◽  
Innovative Method

Surface acoustic wave (SAW) is effective for the manipulation of fluids and particles in microscale. The current approach of integrating interdigitated transducers (IDTs) for SAW generation into microfluidic channels involves complex and laborious microfabrication steps. These steps often require the full access to clean room facilities and hours to align the transducers to the precise location. This work presents an affordable and innovative method for fabricating SAW-based microfluidic devices without the need of clean room facilities and alignment. The IDTs and microfluidic channels are fabricated in the same process and thus precisely self-aligned in accordance with the device design. With the use of the developed fabrication approach, a few types of different SAW-based microfluidic devices have been fabricated and demonstrated for particle separation and active droplet generation.

scholarly journals Rapid Food Product Analysis by Surface Acoustic Wave Nebulization Coupled Mass Spectrometry

2018 ◽  
Vol 11 (9) ◽  
pp. 2447-2454 ◽  
Author(s):  
Thomas Schneider ◽  
Benjamin L. Oyler ◽  
Sung Hwan Yoon ◽  
Tao Liang ◽  
Gloria S. Yen ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Acoustic Wave ◽  
Surface Acoustic Wave ◽  
Food Product ◽  
Product Analysis ◽  
Surface Acoustic Wave Nebulization

Droplet delivery and nebulization system using surface acoustic wave for mass spectrometry

Lab on a Chip ◽  
2020 ◽  
Vol 20 (17) ◽  
pp. 3269-3277
Author(s):  
Di Sun ◽  
Karl F. Böhringer ◽  
Matthew Sorensen ◽  
Erik Nilsson ◽  
J. Scott Edgar ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Sample Preparation ◽  
Acoustic Wave ◽  
Surface Acoustic Wave ◽  
Standing Wave ◽  
Piezoelectric Transducer ◽  
Wave Surface ◽  
Surface Acoustic Wave Nebulization

We present a piezoelectric transducer for standing wave surface acoustic wave nebulization (SW-SAWN) patterned with anisotropic ratchet conveyors (ARCs) to automate the sample preparation and droplet delivery.

Optimized surface acoustic wave nebulization facilitates bacterial phenotyping

2018 ◽  
Vol 427 ◽  
pp. 65-72 ◽  
Author(s):  
Tao Liang ◽  
Thomas Schneider ◽  
Sung Hwan Yoon ◽  
Benjamin L. Oyler ◽  
Lisa M. Leung ◽  
...  
Keyword(s):  
Acoustic Wave ◽  
Surface Acoustic Wave ◽  
Surface Acoustic Wave Nebulization

scholarly journals Effective pulmonary delivery of an aerosolized plasmid DNA vaccine via surface acoustic wave nebulization

2014 ◽  
Vol 15 (1) ◽  
pp. 60 ◽  
Author(s):  
Anushi E Rajapaksa ◽  
Jenny J Ho ◽  
Aisha Qi ◽  
Rob Bischof ◽  
Tri-Hung Nguyen ◽  
...  
Keyword(s):  
Acoustic Wave ◽  
Surface Acoustic Wave ◽  
Dna Vaccine ◽  
Plasmid Dna ◽  
Pulmonary Delivery ◽  
Plasmid Dna Vaccine ◽  
Surface Acoustic Wave Nebulization
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