scholarly journals Optomechanical Microwave Amplification without Mechanical Amplification

2020 ◽  
Vol 13 (1) ◽  
Author(s):  
Martijn A. Cohen ◽  
Daniel Bothner ◽  
Yaroslav M. Blanter ◽  
Gary A. Steele
Keyword(s):  
Mechanical Amplification

Mechanical amplification mechanism of kinesin’s β-domain

2014 ◽  
Vol 543 ◽  
pp. 10-14 ◽  
Author(s):  
Yi-Zhao Geng ◽  
Shu-Xia Liu ◽  
Qing Ji ◽  
Shiwei Yan
Keyword(s):  
Mechanical Amplification ◽  
Amplification Mechanism

A middle ear implant using a piezoelectric stack with mechanical amplification

2010 ◽  
Vol 263 (1-2) ◽  
pp. 239-240
Author(s):  
Eric W. Abel ◽  
Robbie C. Brodie ◽  
Zhigang Wang ◽  
Robert P. Mills ◽  
Duncan J. Bowyer
Keyword(s):  
Middle Ear ◽  
Middle Ear Implant ◽  
Mechanical Amplification

A LOW COST MACRO-MICRO POSITIONING SYSTEM WITH SMA-ACTUATED MICRO STAGE

2007 ◽  
Vol 31 (1) ◽  
pp. 75-95 ◽  
Author(s):  
Eric Ho ◽  
Rob Gorbet
Keyword(s):  
Smart Materials ◽  
Lower Cost ◽  
Position Control ◽  
Low Cost ◽  
Experimental System ◽  
Positioning System ◽  
Positioning Systems ◽  
Mechanical Amplification ◽  
Micro Systems ◽  
Better Than

Macro-micro systems allow high-resolution positioning over greater ranges of operation that would be achievable with precision positioning systems. Piezoceramic actuators have established themselves as the principle technology for commercial micro-positioning applications, and the trend in research is to push the limits of resolution down to the nanometer and sub-nanometer scales. Other smart materials offer the potential for lightweight, continuous actuation over small ranges, and hence may be useful in micro-positioning applications. This work focuses on the potential for SMA actuators to enable low-cost micro-positioning. Compared to piezos, SMA offer longer range and lower actuation voltages, enabling lower-cost drive electronics and removing the need for costly precision mechanical amplification stages. A prototype single-axis macro-micro positioning system is described, with a macro range of 200 mm and relative positioning precision of better than 5 5μm. The micro stage is driven by an NM70 SMA actuator from NanoMuscle. Macro and micro stages are modelled and controllers developed, and experimental system performance is evaluated. The success of the system provides an inexpensive platform for the study of macro-micro positioning issues such as stage coupling, friction, and drive flexibility, as well as for the position control of SMA.

scholarly journals Diverse Roles of Axonemal Dyneins in Drosophila Auditory Neuron Function and Mechanical Amplification in Hearing

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Somdatta Karak ◽  
Julie S. Jacobs ◽  
Maike Kittelmann ◽  
Christian Spalthoff ◽  
Radoslaw Katana ◽  
...  
Keyword(s):  
Auditory Neuron ◽  
Mechanical Amplification ◽  
Neuron Function

scholarly journals Kinetics of small molecule interactions with membrane proteins in single cells measured with mechanical amplification

2015 ◽  
Vol 1 (9) ◽  
pp. e1500633 ◽  
Author(s):  
Yan Guan ◽  
Xiaonan Shan ◽  
Fenni Zhang ◽  
Shaopeng Wang ◽  
Hong-Yuan Chen ◽  
...  
Keyword(s):  
Membrane Proteins ◽  
Small Molecule ◽  
Single Cells ◽  
Cellular Membrane ◽  
Mechanical Amplification ◽  
New Strategy ◽  
Interaction Kinetics ◽  
Molecule Interactions ◽  
Difficult Challenge ◽  
Membrane Protein Interaction

Measuring small molecule interactions with membrane proteins in single cells is critical for understanding many cellular processes and for screening drugs. However, developing such a capability has been a difficult challenge. We show that molecular interactions with membrane proteins induce a mechanical deformation in the cellular membrane, and real-time monitoring of the deformation with subnanometer resolution allows quantitative analysis of small molecule–membrane protein interaction kinetics in single cells. This new strategy provides mechanical amplification of small binding signals, making it possible to detect small molecule interactions with membrane proteins. This capability, together with spatial resolution, also allows the study of the heterogeneous nature of cells by analyzing the interaction kinetics variability between different cells and between different regions of a single cell.

scholarly journals Mechanical Amplification Exhibited by Quiescent Saccular Hair Bundles

2015 ◽  
Vol 108 (1) ◽  
pp. 53-61 ◽  
Author(s):  
Yuttana Roongthumskul ◽  
Dolores Bozovic
Keyword(s):  
Mechanical Amplification ◽  
Hair Bundles

scholarly journals Mathematical modelling of the active hearing process in mosquitoes

2009 ◽  
Vol 7 (42) ◽  
pp. 105-122 ◽  
Author(s):  
D. Avitabile ◽  
M. Homer ◽  
A. R. Champneys ◽  
J. C. Jackson ◽  
D. Robert
Keyword(s):  
Mechanistic Model ◽  
Mosquito Species ◽  
Low Energy ◽  
Acoustic Energy ◽  
The Other ◽  
Critical Amplitude ◽  
Mechanical Amplification ◽  
Nonlinear Amplification ◽  
Gain Loss ◽  
Damped Oscillator

Insects have evolved diverse and delicate morphological structures in order to capture the inherently low energy of a propagating sound wave. In mosquitoes, the capture of acoustic energy and its transduction into neuronal signals are assisted by the active mechanical participation of the scolopidia. We propose a simple microscopic mechanistic model of the active amplification in the mosquito species Toxorhynchites brevipalpis . The model is based on the description of the antenna as a forced-damped oscillator coupled to a set of active threads (ensembles of scolopidia) that provide an impulsive force when they twitch. This twitching is in turn controlled by channels that are opened and closed if the antennal oscillation reaches a critical amplitude. The model matches both qualitatively and quantitatively with recent experiments: spontaneous oscillations, nonlinear amplification, hysteresis, 2 : 1 resonances, frequency response and gain loss owing to hypoxia. The numerical simulations presented here also generate new hypotheses. In particular, the model seems to indicate that scolopidia located towards the tip of Johnston's organ are responsible for the entrainment of the other scolopidia and that they give the largest contribution to the mechanical amplification.

scholarly journals Mechanical Amplification by Non-Oscillating Saccular Hair Cell Bundles

2014 ◽  
Vol 106 (2) ◽  
pp. 597a
Author(s):  
Yuttana Roongthumskul ◽  
Dolores Bozovic
Keyword(s):  
Hair Cell ◽  
Mechanical Amplification
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