scholarly journals The green autofluorescence intensity and asymmetry of older men is significantly higher than those of older women in their fingernails and certain regions of skin

2019 ◽  
Author(s):  
Yue Tao ◽  
Mingchao Zhang ◽  
Danhong Wu ◽  
Yujia Li ◽  
Weihai Ying
Keyword(s):  
Older Women ◽  
Diagnostic Method ◽  
Age Groups ◽  
Older Men ◽  
Disease Diagnosis ◽  
Health State ◽  
Age Group ◽  
Female Population ◽  
Novel Biomarkers ◽  
Left And Right

AbstractOur recent studies have suggested that the patients of multiple diseases have characteristic Pattern of Autofluorescence (AF) in their skin and fingernails, which may become novel biomarkers for both disease diagnosis and evaluation of health state. Since male populations may have higher levels of oxidative stress and inflammation than female population, in our current study we tested our hypothesis that the green AF intensity of older men is higher than that of older women in their fingernails and skin. We found that in both left and right Index Fingernails, the green AF intensity of the men of both the age group of 61 - 70 years of old and the age group of 71 - 80 years of old is significantly higher than that of the women of the same age groups. At both left Dorsal Centremetacarpus and left Centremetacarpus, the green AF intensity of the men at the age between 71 - 80 years of old is also significantly higher than that of the women of the same age group. Moreover, in Index Fingernails, Dorsal Centremetacarpus and Centremetacarpus, the green AF asymmetry of the older men of certain age groups is significantly higher than that of the women of the same age groups. Collectively, our study has provided the first evidence indicating the gender difference between the green AF intensity and asymmetry of older men and those of older women in their fingernails and certain regions of skin, which is valuable for establishing the AF-based diagnostic method.

scholarly journals Can traditional games be an option in increasing the physical activity of women following mastectomy?

2015 ◽  
Vol 7 (1) ◽  
Author(s):  
Małgorzata Bronikowska ◽  
Michał Bronikowski ◽  
Agata Glapa ◽  
Bartosz Prabucki
Keyword(s):  
Physical Activity ◽  
Older Women ◽  
Age Groups ◽  
Recovery Process ◽  
Age Group ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Younger Women ◽  
Younger Age ◽  
Ring Net

SummaryStudy aim: the purpose of the present study was to investigate the potential of traditional games as a method of increasing the physical activity (PA) of women following mastectomy. A cross-sectional survey during the 20th ONCO Games was conducted and the sample included data from women divided into two groups: up to 50 years old (n = 26) and over 50 years old (n = 86).Material and methods: PA was assessed using a questionnaire, and the number of steps taking during 30-minute periods was measured using pedometers during each of the games. Exertion was evaluated using Borg’s Scale.Results: there was no difference in levels of coherence between the age groups. The group of younger women were statistically more active (M = 3.34 days/week) than the older group (M = 2.77 days/week). All the games were evaluated to be of light intensity, with ringo perceived as being statistically more fatiguing in the over 50 age group. The highest number of steps was performed during the game of ring-net-ball (M = 1903 steps/30 min) in both age groups, with older women performing statistically more steps. Similar situations were observed in the cases of pétanque and speedminton. In ringo, the situation was reversed. The lowest number of steps was recorded in pétanque in the younger age group (M = 296 steps/30 min).Conclusion: this study indicates that in the rehabilitation and recovery process after mastectomy, traditional games could be a bridging link between exercising and sports as they provide not just activity but also a unique and valuable social context.

Quality of life in young men after radical prostatectomy: Results from the CaPSURE registry

2006 ◽  
Vol 24 (18_suppl) ◽  
pp. 4576-4576 ◽  
Author(s):  
J. L. Wright ◽  
D. W. Lin ◽  
J. E. Cowan ◽  
J. Duchane ◽  
P. R. Carroll ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
Age Groups ◽  
Older Men ◽  
Multivariate Model ◽  
Age Group ◽  
Younger Men ◽  
One Year

4576 Background: Over the past two decades, the age at diagnosis and treatment of men with prostate cancer (CaP) has steadily declined. Previous work suggests that younger men have similar or improved pathologic and clinical outcomes compared to older men. The literature on quality of life (QOL) following local treatment for CaP has primarily focused on comparing treatment modalities rather than specific age groups. This analysis explored QOL outcomes in younger men following primary curative treatment for localized prostate cancer. Methods: This was a secondary analysis of a prospectively collected cohort from the CaPSURE (Cancer of the Prostate Strategic Urologic Endeavor) registry. Men who underwent radical prostatectomy (RP) for localized disease and completed the UCLA Prostate Cancer Index (PCI) pre- and one-year post-surgery were identified. Men were grouped based on age (< 55, 55–64, ≥ 65 years). A severe decline in PCI domains from pre- to post-RP was defined as a decrease of one standard deviation from the pre-RP score. PCI scores were compared across age groups, and a multivariate model created to analyze the predictors of severe declines in PCI domains. Results: 1,143 men were identified, with 190, 526 and 427 men in the three age groups, respectively. Younger men had significantly higher mean scores one-year after RP in the urinary function (UF), urinary bother (UB) and sexual function (SF) domains of the PCI. The proportion of men with a severe decline in UF, UB and SF was not significantly different in the age groups (range 49–54%, 32–38%, 58–51% respectively). However, a severe decline in SB was more common in the youngest age group than in the oldest (54% vs. 36%, p < 0.01). With the youngest men as the reference group in the multivariate model, the oldest age group was 40% less likely to have a severe decline of SB (OR = 0.60, 95% CI 0.41–0.90, p = 0.04) but trended toward a higher risk of severe decline in UB (OR = 1.27, 95% CI 0.85–1.89, p = 0.08). Conclusions: Age predicts disease-specific QOL changes at one-year following RP. Younger men had significantly better mean UF, UB, and SF domain scores one-year after RP than did their older counterparts. Men < 55 years old are more likely than older men to experience a severe decline of sexual bother but trend toward a lower risk of a severe urinary bother. No significant financial relationships to disclose.

The changing face of cancer in the elderly—Only a demographic change?

2006 ◽  
Vol 24 (18_suppl) ◽  
pp. 18597-18597
Author(s):  
Y. Rottenberg ◽  
T. Peretz
Keyword(s):  
Breast Cancer ◽  
Prostate Cancer ◽  
Lung Cancer ◽  
Older Women ◽  
Age Groups ◽  
The Elderly ◽  
Age Group ◽  
Industrial Countries ◽  
Cancer Burden ◽  
Two Age Groups

18597 Background: In industrial countries, the cancer burden of the elderly is high and is increased. One reason is longer life expectancy. Increasing age standardized rates of cancer in this age group compared to younger groups may also explain this phenomenon. Methods: Two age groups were examined, above and below 65 years. Each age group was further divided into men and women. The age standardized rates for all cancers combined among the Jewish population in Israel were identified through the Israel Cancer Registry during the years 1973–2002. In addition, lung and colorectal cancers according to sexes, prostate cancer in men and breast cancer in women were examined. Results: Between the first 5 years of the study (1973–1977) and the last 5 years (1998–2002) the age standardized rates for all cancers combined were raised by about one third in the two age groups. In males, the overall change was higher in the older group (42% in men aged 65 years and older compared to 31% in men younger than 65). However, the rise in the younger group was more prominent in females (42% in women younger than 65 years compared to 33 % in women aged 65 and older). The most outstanding increase was in prostate cancer in men, but mainly in the younger group (176% in the older group and 368% in the younger group) followed by breast cancer in women, more prominent in the older group (64% in the older group and 50% in the younger group). In both sexes, more noticeable increases were noted in the older groups in colorectal cancer and in lung cancer. Between the years 1993–1997 and 1998–2002 shifts towards stabilization and even a decrease was noted in some of the cancers that were examined. In men aged 65 years and older rates for all cancers combined were decreased by 2.5%, among the specific tumors and a decrease was noted in lung cancer (6.7%) and prostate cancer (5.8%). The rates for all cancers combined among the older women were slightly decreasing (2.0%). No decrease was noted in the specific tumors in this group. Among the younger groups in both sexes, no decrease (defined >0.5%) was noted. Conclusions: These data argue against the hypothesis that the overall change in the cancer burden in the aged could be also explained by differences changes in the risk of developing cancer between these two age groups. No significant financial relationships to disclose.

scholarly journals Oral Health Matters- Tooth Problem and its Treatment-seeking Behaviour Among Older Adults in India

2020 ◽  
Author(s):  
Shobhit Srivast ◽  
Pradeep Kumar ◽  
Debashree Sinha ◽  
Prem Shankar Mishra
Keyword(s):  
Older Adults ◽  
Oral Health ◽  
Older Women ◽  
Dental Health ◽  
National Level ◽  
Negative Relationship ◽  
Older Men ◽  
Health Problems ◽  
Effective Sample Size ◽  
Age Group

Abstract Background: Growing untreated morbidities among the older adults on geriatric issues especially an optimal dental treatment has become an unfinished agenda and a long-neglected area for care and management in many low and middle-income countries. There is a continuous rise in the older population in India and at the same time, the rising of co-morbidities or multi-morbidities in the aging population creates catastrophic challenges at the individuals, household, community, and country levels, and therefore, it is important to address dental health problems and related issues in the aged population in India. The study aims to understand the prevalence of dental health problems and their health-seeking behaviour among older adults in India. Further, the study determines the factors associated with low access and under-coverage of dental health care services among the elderly populations in IndiaMethods: The present research used data from Building a Knowledge Base on Population Aging in India (BKPAI) which was a national level survey and was conducted in 2011, across seven states of India. The effective sample size of this study was 9541 older adults aged 60+ years. Descriptive statistics and bivariate analysis were used to fulfill the study objectives. Additionally, the study employed the Heckprobit selection model which is a two-equation model to understand the determinants of dental health problems.Results: Older adults in the age group of 70-79 years (36.9%) and 80+ years (51.9%) reported higher dental problems compared to 60-69 years (19.9%), older women reported more dental problems (29.2%) and also used more dental aids (12.6%) compared to older men. Older adults in the age group 70-79 and 80+ years were 0.15 times and 0.40 times less likely to use dental aids respectively, as compared to 60-69 years older adults. Moreover, older women were 0.28 times more likely to use dental aids than older men. Education and wealth of older adults have a negative relationship with dental problems.Conclusion: This study clearly emphasized that awareness of smoking-related health problems should be promoted vigorously. Further, a holistic approach is needed to prevent dental diseases that occur because of other co-morbidities. For that, integration of the oral health program with programs dealing with morbidities can act as a solution to the existing problem.

scholarly journals Age and Gender Specific Lung Cancer Incidence and Mortality in Hungary: Trends from 2011 Through 2016

2021 ◽  
Vol 27 ◽  
Author(s):  
Lilla Tamási ◽  
Krisztián Horváth ◽  
Zoltán Kiss ◽  
Krisztina Bogos ◽  
Gyula Ostoros ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Age Groups ◽  
Age Group ◽  
Lung Cancer Incidence ◽  
Age And Gender ◽  
Female Population ◽  
Incidence And Mortality ◽  
Icd 10 ◽  
And Gender ◽  
Gender Specific

Objective: No assessment was conducted describing the age and gender specific epidemiology of lung cancer (LC) prior to 2018 in Hungary, thus the objective of this study was to appraise the detailed epidemiology of lung cancer (ICD-10 C34) in Hungary based on a retrospective analysis of the National Health Insurance Fund database.Methods: This longitudinal study included patients aged ≥20 years with LC diagnosis (ICD-10 C34) between January 1, 2011 and December 31, 2016. Patients with different cancer-related codes 6 months before or 12 months after LC diagnosis or having any cancer treatment other than lung cancer protocols were excluded.Results: Lung cancer incidence and mortality increased with age, peaking in the 70–79 age group (375.0/100,000 person-years) among males, while at 60–69 age group for females (148.1/100,000 person-years). The male-to-female incidence rate ratio reached 2.46–3.01 (p &lt; 0.0001) among the 70–79 age group. We found 2–11% decrease in male incidence rate at most age groups, while a significant 1–3% increase was observed in older females (&gt;60) annually during the study period.Conclusion: This nationwide epidemiology study demonstrated that LC incidence and mortality in Hungary decreased in younger male and female population, however we found significant increase of incidence in older female population, similar to international trends. Incidence rates peaked in younger age-groups compared to Western countries, most likely due to higher smoking prevalence in these cohorts, while lower age LC incidence could be attributed to higher competing cardiovascular risk resulting in earlier mortality in smoking population.

scholarly journals The interaction of age and gender in illness narratives

2008 ◽  
Vol 28 (7) ◽  
pp. 1025-1045 ◽  
Author(s):  
CLIVE SEALE ◽  
JONATHAN CHARTERIS-BLACK
Keyword(s):  
Older Women ◽  
Medical Information ◽  
Elderly Care ◽  
Age Groups ◽  
Older Men ◽  
Family Networks ◽  
Emotional Dimension ◽  
Younger Men ◽  
Research Interviews ◽  
And Gender

ABSTRACTRecognition of the greater capacity of older women to draw on supportive social networks has now supplemented an earlier focus of research into gender and ageing which portrayed older men as a ‘privileged gerontocracy’ because of their greater access to financial resources and spousal care. This study of the experiences of cancer among people of three different age groups conducted a comparative keyword analysis of their narratives to consider the gender differentiation of a third resource: access to medical information and personnel. The analysed narratives were sampled from a large archive of research interviews. It was found that older men with cancer demonstrated a greater involvement with medicine as an expert system than younger men or women or older women. This stemmed from their social confidence when interacting with doctors and their interest in treating their illness as a ‘problem’ to be fixed with medico-scientific solutions. Compared with younger men and women of all ages, older men were less likely to draw on informal social and family networks for support, or to discuss in a direct style the emotional dimension of illness experience. Our findings contrast with other studies that have reported linguistic disadvantage in older people in elderly care settings, which underlines the importance of context for linguistic studies.

Phenotype and treatment of elderly onset compared to younger onset rheumatoid arthritis patients in international daily practice

Rheumatology ◽  
2021 ◽  
Author(s):  
Johanna M Maassen ◽  
Sytske Anne Bergstra ◽  
Arvind Chopra ◽  
Nimmisha Govind ◽  
Elizabeth A Murphy ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Initial Treatment ◽  
Cox Regression ◽  
Disease Onset ◽  
Age Groups ◽  
International Study ◽  
Daily Practice ◽  
Disease Diagnosis ◽  
Response To Treatment ◽  
Age Group

Abstract Objective To identify possible differences in baseline characteristics, initial treatment and treatment response between rheumatoid arthritis (RA) patient subgroups based on age at disease onset. Methods Daily practice data from the worldwide METEOR registry were used. Patients (7,912) were stratified into three age-groups (age at disease diagnosis &lt;45 years; 45-65 years; &gt;65 years). Initial treatment was compared between the different age-groups. With Cox regression analyses the effect of age-group on time-to-switch from first to second treatment was investigated, and with linear mixed models differences in response to treatment (DAS and HAQ) between the age-groups were assessed, after correction for potential confounders. Results The &gt;65 years age-group included more men, more seronegative RA with somewhat higher inflammatory markers. Initial treatment choices differed only slightly between the age-groups, and the time-to-switch from initial treatment to the next was similar. DAS and HAQ improvement were dependent on the age-group, reflected by a significant interaction between age-group and outcome. The stratified analysis showed a difference of -0.02 and -0.05 DAS points and, -0.01 and 0.02, HAQ points per month in the &lt;45y and 45-65y age-groups as compared to the &gt;65y age group. A difference that did not seem clinically relevant. Conclusion In this international study on worldwide clinical practice, patients with RA onset &gt;65 years include more men and seronegative arthritis, and were initially treated slightly different than younger patients. We observed no clinically relevant differences in timing of a next treatment step, or response to treatment measured by DAS and HAQ.

scholarly journals Serodiagnostic Investigation of Syphilis in Taluka Gambat

2020 ◽  
Vol 10 (2) ◽  
pp. 76-81
Author(s):  
Sagheer Hussain Shah ◽  
Agha Asad Noor
Keyword(s):  
Congenital Syphilis ◽  
Age Groups ◽  
Laboratory Diagnosis ◽  
Morbidity Rate ◽  
Age Group ◽  
Serum Samples ◽  
Transmitted Infection ◽  
Serological Method ◽  
Female Population ◽  
Sexually Transmitted

Background: Syphilis is a chronic and sexually transmitted infection, caused by Treponema pallidum. Taluka Gambat is an under developing rural area of District Khairpur, Sindh having higher poverty rate. This study was undertaken to assess the morbidity rate of syphilis and awareness about this disease in the population of Gambat. Objectives: To investigate the prevalence of syphilis in various age groups of male and female population of Taluka Gambat to review the frequency of occurrence of syphilis. Methodology: This work was done using conventional serological method by collecting data and laboratory diagnosis. Total 437 serum samples from different private and public health units, dispensaries and hospitals in Taluka Gambat were collected between October 2016 to March 2017 and subjected to qualitative testing by VDRL-Immune Chromatography test. Results: Out of 437 samples, 80 samples (18%) were reactive in adults of 30-45 years of age and one sample showed positive case in 9 months old boy indicating congenital syphilis (0.2%) whereas 373 stood non-reactive.  Our results showed a 14% prevalence of syphilis in Taluka Gambat in the age group between 30-45 years of age and 0.2% congenital syphilis. It is an alarming situation due to lack of diagnostic, treatment facilities and awareness about sexually transmitted diseases (STDs). Conclusion: It is concluded that syphilis is found more or less in all age groups. The highest incidence is observed in population of age group between 30-40 years in Taluka Gambat. Majority infections were found in immunocompromised patients owing to drug abuse and having multiple sex partners.

scholarly journals Prevalence of Intrinsic and Extrinsic Factors Contributing to Causing of Functional Decline in Elderly Individuals in the Rural Population of Karad, India

2021 ◽  
Vol 10 (33) ◽  
pp. 2697-2701
Author(s):  
Urwashi Kamal Kant Baurai ◽  
Malti Vijay Bhambure ◽  
Anandh Srinivasana
Keyword(s):  
Prevalence Rate ◽  
Functional Decline ◽  
Age Groups ◽  
Mean Value ◽  
Age Group ◽  
Extrinsic Factors ◽  
Female Population ◽  
Intrinsic Factors ◽  
Validated Questionnaire ◽  
Intrinsic And Extrinsic Factors

BACKGROUND Functional decline refers to increase in dependence towards activities of daily living and is common with increasing age, chronic diseases, and previous hospitalization. We wanted to determine the rate of intrinsic and extrinsic factors of functional decline in different age groups among elderly population and in relation to gender. METHODS The study population was composed of 64 individuals which were above the age group of 60 years, further subdivided into 3 groups: 60 - 70, 70 - 80 and 80 years and above. The validated questionnaire was provided through which the intrinsic and extrinsic factors were determined. RESULTS In all the studied subjects, extrinsic factors had a mean value of 31.24 % while intrinsic factors had a mean value of 28.12 % which indicates that extrinsic factors are more prevalent than intrinsic factors in all the age groups. Both intrinsic and extrinsic factors were more prevalent in the female population than the male population with the prevalence rate of intrinsic factors as 34.37 % in males and 50 % in females and for the extrinsic factors prevalence rate of 39.06 % in males and 54.68 % in females. In age group of 60 – 70 yrs. we found that the prevalence of intrinsic factors was (23.43 %) and extrinsic was (26.56 %), for 70 - 80 intrinsic it was (29.68 %) extrinsic was (32.81 %) and for 80 and above prevalence intrinsic was (31.25 %) and extrinsic was (34.37 %). CONCLUSIONS The study showed that the extrinsic factors contributed more to the functional decline as compared to the intrinsic factors. These findings are important as the functional decline and increasing care needs are potentially modifiable. KEY WORDS Functional Decline, Intrinsic Factors, Extrinsic Factors, Disability

scholarly journals Changes in Hysterectomy Route and Adnexal Removal for Benign Disease in Australia 2001–2015: A National Population-Based Study

2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Natalie De Cure ◽  
Stephen J. Robson
Keyword(s):  
Age Groups ◽  
Laparoscopic Hysterectomy ◽  
Abdominal Hysterectomy ◽  
Population Based ◽  
Incidence Rates ◽  
Older Age ◽  
Age Group ◽  
Female Population ◽  
Younger Women ◽  
Younger Age

Objective. Hysterectomy rates have fallen over recent years and there remains debate whether salpingectomy should be performed to reduce the lifetime risk of ovarian cancer. We examined trends in adnexal removal and route of hysterectomy in Australia between 2001 and 2015. Methods. Data were obtained from the national procedural dataset for hysterectomy approach (vaginal, VH; abdominal, AH; and, laparoscopic, LH) and rates of adnexal removal, as well as endometrial ablation. The total female population in two age groups (“younger age group,” 35 to 54 years, and “older age group,” 55 to 74 years) was obtained from the Australian Bureau of Statistics. Results. The rate of hysterectomy fell in both younger (61.7 versus 45.2/10000/year, p<0.005) and older (38.8 versus 33.2/10000/year, p<0.005) age groups. In both age groups there were significant decreases in the incidence rates for VH (by 53% in the younger age group and 29% in the older age group) and AH (by 53% and 55%, respectively). The rates of LH increased by 153% in the younger age group and 307% in the older age group. Overall, the proportion of hysterectomies involving adnexal removal increased (31% versus 65% in the younger age group, p<0.005; 44% versus 58% in the older age group, p<0.005). The increase occurred almost entirely after 2011. Conclusion. Hysterectomy is becoming less common, and both vaginal and abdominal hysterectomy are being replaced by laparoscopic hysterectomy. Removal of the adnexae is now more common in younger women.

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