scholarly journals Cognitive functions and jugular venous reflux in severe mitral regurgitation

2018 ◽  
Author(s):  
Shih-Hsien Sung ◽  
Ching-Wei Lee ◽  
Pei-Ning Wang ◽  
Hsiang-Ying Lee ◽  
Chen-Huan Chen ◽  
...  

AbstractCardiac diseases with elevated central venous pressure have higher frequency of jugular venous reflux (JVR), which is associated with decreased cerebral blood flow and white matter hyperintensities. Whether patients with severe mitral-regurgitation (SMR) have poorer cognitive functions and whether JVR is involved were determined. Patients with SMR and age/sex-matched controls were prospectively recruited. Neuropsychological tests such as global cognitive (Mini-Mental State Examination, MMSE), verbal memory, executive, and visuospatial domains were performed. Cardiac parameters by cardiac catheterisation and echocardiography, and the frequency of JVR by colour-coded duplex ultrasonography were obtained. Forty patients with SMR and 40 controls (71.1±12.2, 38–89 years; 75% men) were included. Compared with the controls, patients with SMR had lower scores in all neuropsychological tests but only MMSE and visuospatial test scores were statistically significant after adjusting for age, sex, and educational level. We further adjusted for cardiovascular risk factors; the significance remained in the visuospatial test but diminished in MMSE. Multivariate linear regression analyses adjusted for age, sex, and educational level showed that JVR combined with high right-atrial-pressure (RAP > 50th-percentile, 12 mmHg) was significantly associated with poorer performances in both MMSE [right JVR: B coefficient(95% confidence interval, p)=-2.83(−5.46–0.20, 0.036); left JVR: −2.77(−5.52–0.02, 0.048)] and visuospatial test [right JVR: −4.52(−8.89–0.16, 0.043); left JVR: −4.56(−8.81–0.30, 0.037)], with significances that remained after further adjusting for cardiovascular risk factors. Our results suggest that retrogradely-transmitted venous pressure might be involved in the mechanisms mediating the relationship between cardiac diseases and brain functions.

PLoS ONE ◽  
2019 ◽  
Vol 14 (2) ◽  
pp. e0207832 ◽  
Author(s):  
Shih-Hsien Sung ◽  
Ching-Wei Lee ◽  
Pei-Ning Wang ◽  
Hsiang-Ying Lee ◽  
Chen-Huan Chen ◽  
...  

2011 ◽  
Vol 21 (8) ◽  
pp. 555-563 ◽  
Author(s):  
Ana Redondo ◽  
Joan Benach ◽  
Isaac Subirana ◽  
José Miguel Martinez ◽  
Miguel Angel Muñoz ◽  
...  

Global Heart ◽  
2018 ◽  
Vol 13 (4) ◽  
pp. 515
Author(s):  
I.P.B. Aragão ◽  
E.C.S. Peixoto ◽  
R.T.S. Peixoto ◽  
R.T.S. Peixoto ◽  
S.A. Simões ◽  
...  

Author(s):  
Erdem Erkoyun ◽  
J P Mackenbach

Abstract Background We aimed to investigate the magnitude of occupational class (OC) and educational level (EL) inequalities in cardiovascular risk factors in Turkey from 2008 to 2016 and compare these inequalities with neighbouring European countries. Methods We used the Turkey Health Survey among a representative sample of the Turkish population. We estimated relative index of inequality (RII) for four cardiovascular risk factors (obesity/overweight, hypertension, diabetes, smoking) by OC/EL with an interaction term for survey year and compared selected results with neighbouring countries. Results Men with lower OC and EL smoked more (e.g. RII for EL = 1.40 [1.26–1.55]); however, the remaining risk factors were mostly lower in these groups. Women in lower socio-economic groups smoked less (e.g. RII for EL = 0.36 [0.29–0.44]), however, had higher prevalence of the remaining risk factors. Significant interactions with survey year were only found in a few cases. The pattern of inequalities in Turkey is largely similar to neighbouring countries. Conclusions Inequalities in cardiovascular risk factors are less systematic in Turkey than in most high-income countries, but ongoing trends suggest that this may change in the future.


Author(s):  
Rute Pires Costa ◽  
Pedro Antônio Muniz Ferreira ◽  
Francisco das Chagas Monteiro Junior ◽  
Adalgisa de Sousa Paiva Ferreira ◽  
Valdinar Sousa Ribeiro ◽  
...  

2017 ◽  
Vol 17 (2) ◽  
pp. 136-147 ◽  
Author(s):  
Anastase Tchicaya ◽  
Nathalie Lorentz ◽  
Stefaan Demarest ◽  
Jean Beissel

Background: Cardiovascular diseases are important causes of death, morbidity, and years of potential life lost in most developed countries. Aims: The purpose of this study was to assess trends in knowledge of cardiovascular risk factors among patients five years after coronary angiography and to investigate the impact of educational level on knowledge level. Methods: The study included 1289 of 4391 patients admitted for cardiac events in 2008/2009 at the National Institute for Cardiac Surgery and Interventional Cardiology, Luxembourg. A follow-up study was conducted by post five years later (2013/2014). Data were obtained from 1837 of the contacted patients (with 548 reported deaths) (response rate=42%). Logistic regression models were used to evaluate the association between educational level and knowledge of cardiovascular risk factors. Educational level was used as a surrogate for socioeconomic status. Results: In total, 39.9% of patients could list at least three risk factors in 2013/2014, a much higher percentage than the 8.5% observed during the initial survey. In both sexes, knowledge of cardiovascular risk factors increased between 2008/2009 and 2013/2014. Patients with higher educational levels were more likely (odds ratio=2.33, 95% confidence interval: 1.63–3.34) to cite at least three risk factors than patients with lower education levels. Conclusion: Knowledge level was associated with educational level, and improved for all educational groups five years after coronary angiography. Educational differences in knowledge persisted, but the gaps decreased. Improving knowledge of cardiovascular risk factors among patients with cardiovascular disease will help increase awareness and promote lifestyle changes.


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