scholarly journals Physical sciences at Diamond: past achievements and future opportunities

2015 ◽  
Vol 373 (2036) ◽  
pp. 20130150 ◽  
Author(s):  
D. F. McMorrow
Keyword(s):  
Light Source ◽  
Third Generation ◽  
Physical Sciences ◽  
Personal View ◽  
X Ray ◽  
The Third ◽  
The Uk

The start of user operation at the Diamond Light Source in January 2007 marks a major milestone for the physical sciences in the UK. The routine delivery to the UK community of ultra-bright X-ray beams from the third-generation source has provided us with capabilities that were available previously only at international sources, and indeed has created some that are unique. Here, a personal view is given of some of the achievements to date, and possible future opportunities outlined.

scholarly journals I04-1, a future 'fragment screening' beamline facility at Diamond Light Source

2014 ◽  
Vol 70 (a1) ◽  
pp. C790-C790
Author(s):  
Alice Douangamath ◽  
Jose Brandao-Neto ◽  
Mark Williams ◽  
Richard Fearn ◽  
Tobias Krojer ◽  
...  
Keyword(s):  
Light Source ◽  
Macromolecular Crystallography ◽  
New Developments ◽  
X Ray ◽  
X Ray Crystallography ◽  
Fragment Screening ◽  
The Third ◽  
Synchrotron Light ◽  
Set Up ◽  
The Uk

I04-1 is one of the six macromolecular crystallography (MX) beamlines at Diamond Light Source (DLS), the third generation synchrotron light source in the UK. It was built and delivered in 2010 as a stable and reliable fixed-wavelength MX station. It is currently preparing to release its user programme for exploiting fragment screening using X-ray crystallography in structural medicinal chemistry projects. For this purpose, the beamline has been going through several upgrades in order to achieve unattended high-throughput ligand crystallography. The new developments are aiming at improving the flux, stability and reliability of the beamline and its auto-alignment. In parallel, a peripheral laboratory is being set up to provide a facility for medium throughput compound soaking. Jointly with the Structural Genomics Consortium (SGC), a semi-automatic crystal soaking and harvesting scheme, which will provide hundreds of MX samples per day, is being tested at DLS. The beamline can currently process 400 crystals per day. However, the recent upgrades and automation should further improve that throughput. In this presentation, we will summarise the current specifications of the beamline and its new features, the development of a peripheral laboratory for compounds soaking and underline the remaining work.

scholarly journals Updated plans for DIAMOND, a new X-ray light source for the UK

2002 ◽  
Author(s):  
V.P. Suller ◽  
J.A. Clarke ◽  
J.B. Fitzgerald ◽  
H.L. Owen ◽  
M.W. Poole ◽  
...  
Keyword(s):  
Light Source ◽  
X Ray ◽  
The Uk

Tune optimization of the third generation light source storage ring based on Frequency Map Analysis

2009 ◽  
Vol 33 (3) ◽  
pp. 224-231
Author(s):  
Tian Shun-Qiang ◽  
Liu Gui-Min ◽  
Li Hao-Hu ◽  
Hou Jie ◽  
Zhang Wen-Zhi
Keyword(s):  
Light Source ◽  
Storage Ring ◽  
Third Generation ◽  
The Third ◽  
Frequency Map ◽  
Map Analysis ◽  
Frequency Map Analysis

XLA-200: the third-generation ArF MOPA light source for immersion lithography

2005 ◽  
Author(s):  
Toshihiko Ishihara ◽  
Robert Rafac ◽  
Wayne J. Dunstan ◽  
Fedor Trintchouk ◽  
Christian Wittak ◽  
...  
Keyword(s):  
Light Source ◽  
Third Generation ◽  
Immersion Lithography ◽  
The Third

Certification of Standard Reference Material 1976B

2015 ◽  
Vol 30 (3) ◽  
pp. 199-204 ◽  
Author(s):  
David R. Black ◽  
Donald Windover ◽  
Marcus H. Mendenhall ◽  
Albert Henins ◽  
James Filliben ◽  
...  
Keyword(s):  
Reference Material ◽  
Powder Diffraction ◽  
Standard Reference Materials ◽  
Third Generation ◽  
Line Position ◽  
X Ray ◽  
The Third ◽  
Intensity Measurements ◽  
Peak Intensity ◽  
Relative Peak Intensity

The National Institute of Standards and Technology (NIST) certifies a suite of Standard Reference Materials (SRMs) to address specific aspects of the performance of X-ray powder diffraction instruments. This report describes SRM 1976b, the third generation of this powder diffraction SRM. SRM 1976b consists of a sintered alumina disc, approximately 25.6 mm in diameter by 2.2 mm in thickness, intended for use in the calibration of X-ray powder diffraction equipment with respect to line position and intensity as a function of 2θ-angle. The sintered form of the SRM eliminates the effect of sample loading procedures on intensity measurements. Certified data include the lattice parameters and relative peak intensity values from 13 lines in the 2θ region between 20° and 145° using CuKα radiation. A NIST-built diffractometer, incorporating many advanced and unique design features was used to make the certification measurements.

A Prospect and Retrospect – the Japanese Case

1998 ◽  
Vol 5 (3) ◽  
pp. 140-146 ◽  
Author(s):  
Taizo Sasaki
Keyword(s):  
Synchrotron Radiation ◽  
Light Source ◽  
Research Area ◽  
Third Generation ◽  
Electron Synchrotron ◽  
New Era ◽  
X Ray ◽  
History Of ◽  
Technical Innovations ◽  
Radiation Research

The early through recent history of synchrotron radiation research in Japan, since the initial efforts in 1962, is reviewed. Following a period of parasitic use of an electron synchrotron, Japanese users attempted to build a storage ring as a dedicated soft X-ray source, which was completed in 1974. It opened up a new era of second-generation synchrotron radiation research. The Photon Factory, a dedicated X-ray source commissioned in 1982, provided a much wider research area as well as a number of technical innovations, among which insertion devices brought the further prospect of significant improvements in the properties of sources. As a consequence, the new concept of a light source oriented towards full exploitation of insertion devices, or the idea of a third-generation source, was created. The motivations and developments which led to Spring-8, a third-generation Japanese X-ray source that is currently being commissioned, will be reviewed briefly.

Synchrotron radiation biomedical imaging and radiotherapy: from the UK to the Antipodes

2019 ◽  
Vol 377 (2147) ◽  
pp. 20180240 ◽  
Author(s):  
Christopher Hall ◽  
Robert Lewis
Keyword(s):  
Synchrotron Radiation ◽  
Clinical Diagnostics ◽  
X Rays ◽  
X Ray Diffraction ◽  
Personal View ◽  
X Ray ◽  
Medical Physicists ◽  
The Uk ◽  
A Minor ◽  
Disciplinary Group

Although the general public might think of ‘X-rays’ as they are applied to imaging (radiography) and for the treatment of disease (radiotherapy), the use of synchrotron radiation (SR) X-ray beams in these areas of science was a minor activity 50 years ago. The largest gains in science from SR were seen to be in those areas where signals were weakest in laboratory instruments, such as X-ray diffraction and spectroscopy. As the qualities of SR X-rays were explored and more areas of science adopted SR-based methods, this situation changed. About 30 years ago, the clinical advantages of using SR X-ray beams for radiography, radiotherapy and clinical diagnostics started to be investigated. In the UK, a multi-disciplinary group, consisting of clinicians, medical physicists and other scientists working mainly with the Synchrotron Radiation Source (SRS) in Cheshire, started to investigate techniques for diagnosis and potentially a cure for certain cancers. This preliminary work influenced the design of new facilities being constructed around the world, in particular the Imaging and Medical Beam Line on the Australian Synchrotron in Melbourne. Two authors moved from the UK to Australia to participate in this exciting venture. The following is a personal view of some of the highlights of the early-year SRS work, following through to the current activities on the new facility in Australia. This article is part of the theme issue ‘Fifty years of synchrotron science: achievements and opportunities’.

The Canadian Light Source — History and scientific prospects

2004 ◽  
Vol 82 (6) ◽  
pp. 1028-1042 ◽  
Author(s):  
G M Bancroft
Keyword(s):  
Light Source ◽  
X Rays ◽  
X Ray ◽  
The Third ◽  
Scientific Disciplines ◽  
The World ◽  
History Of ◽  
Synchrotron Light ◽  
Under Construction ◽  
The University

The Canadian Light Source (CLS) in Saskatoon has been under construction for the last 4 years, and will be producing a number of very intense beams of far-IR, IR, soft and hard X-rays in 2004 for use by several hundred Canadian scientists in chemistry, surface and material science, and a host of other scientific disciplines. The CLS will dramatically enhance the Canadian spectroscopic tradition that Gerhard Herzberg help create. I begin this article (from my 2002 CIC Montreal Medal lecture) with an overview of the history of SR in Canada, beginning in 1972 with the first Canadian synchrotron workshop organized at the University of Western Ontario by Bill McGowan, and attended by Dr. Herzberg. The CLS facility is then described, along with the properties of the first and second set of beamlines to be built at the CLS. These SR beams, in the IR and X-ray regions from the third generation CSL ring, will be competitive in brightness and intensity with the best beamlines in the world for most applications. Finally, some of the present Canadian SR research at foreign SR sources is described across the entire SR spectrum. All known spectroscopic and diffraction experiments are dramatically enhanced with SR; and SR opens up new areas of spectroscopy, microscopy, and spectromicroscopy that cannot be studied with any other source of radiation.Key words: synchrotron light, X-rays, infrared, spectroscopy.

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