scholarly journals Harnessing alternative sources of antimicrobial resistance data to support surveillance in low-resource settings

2018 ◽  
Vol 74 (3) ◽  
pp. 541-546 ◽  
Author(s):  
Elizabeth A Ashley ◽  
Nandini Shetty ◽  
Jean Patel ◽  
Rogier van Doorn ◽  
Direk Limmathurotsakul ◽  
...  
Keyword(s):  
Antimicrobial Resistance ◽  
Low Resource Settings ◽  
Low Resource ◽  
Alternative Sources ◽  
Resistance Data

scholarly journals The good and the bad: using C reactive protein to distinguish bacterial from non-bacterial infection among febrile patients in low-resource settings

2020 ◽  
Vol 5 (5) ◽  
pp. e002396 ◽  
Author(s):  
Camille Escadafal ◽  
Sandra Incardona ◽  
B Leticia Fernandez-Carballo ◽  
Sabine Dittrich
Keyword(s):  
Antimicrobial Resistance ◽  
Low Income ◽  
Bacterial Infections ◽  
Laboratory Diagnostics ◽  
Antibiotic Prescribing ◽  
Health Coverage ◽  
C Reactive Protein ◽  
Low Resource Settings ◽  
Low Resource ◽  
Reactive Protein

C reactive protein (CRP), a marker for the presence of an inflammatory process, is the most extensively studied marker for distinguishing bacterial from non-bacterial infections in febrile patients. A point-of-care test for bacterial infections would be of particular use in low-resource settings where other laboratory diagnostics are not always available, antimicrobial resistance rates are high and bacterial infections such as pneumonia are a leading cause of death. This document summarises evidence on CRP testing for bacterial infections in low-income and middle-income countries (LMICs). With a push for universal health coverage and prevention of antimicrobial resistance, it is important to understand if CRP might be able to do the job. The use of CRP polarised the global health community and the aim of this document is to summarise the ‘good and the bad’ of CRP in multiple settings in LMICs. In brief, the literature that was reviewed suggests that CRP testing may be beneficial in low-resource settings to improve rational antibiotic use for febrile patients, but the positive predictive value is insufficient to allow it to be used alone as a single tool. CRP testing may be best used as part of a panel of diagnostic tests and algorithms. Further studies in low-resource settings, particularly with regard to impact on antibiotic prescribing and cost-effectiveness of CRP testing, are warranted.

scholarly journals A Review of Antimicrobial Resistance in Poultry Farming within Low-Resource Settings

Animals ◽  
2020 ◽  
Vol 10 (8) ◽  
pp. 1264 ◽  
Author(s):  
Hayden D. Hedman ◽  
Karla A. Vasco ◽  
Lixin Zhang
Keyword(s):  
Antimicrobial Resistance ◽  
Bacterial Resistance ◽  
Animal Husbandry ◽  
Future Research ◽  
Small Scale ◽  
Human Populations ◽  
Poultry Production ◽  
Low Resource Settings ◽  
Low Resource ◽  
Poultry Farming

The emergence, spread, and persistence of antimicrobial resistance (AMR) remain a pressing global health issue. Animal husbandry, in particular poultry, makes up a substantial portion of the global antimicrobial use. Despite the growing body of research evaluating the AMR within industrial farming systems, there is a gap in understanding the emergence of bacterial resistance originating from poultry within resource-limited environments. As countries continue to transition from low- to middle income countries (LMICs), there will be an increased demand for quality sources of animal protein. Further promotion of intensive poultry farming could address issues of food security, but it may also increase risks of AMR exposure to poultry, other domestic animals, wildlife, and human populations. Given that intensively raised poultry can function as animal reservoirs for AMR, surveillance is needed to evaluate the impacts on humans, other animals, and the environment. Here, we provide a comprehensive review of poultry production within low-resource settings in order to inform future small-scale poultry farming development. Future research is needed in order to understand the full extent of the epidemiology and ecology of AMR in poultry within low-resource settings.

Diagnosis of neonatal sepsis in low resource settings: C-reactive protein or procalcitonin?

2016 ◽  
Vol 03 (02) ◽  
pp. 079-083
Author(s):  
Lawrence Mbuagbaw ◽  
Francisca Monebenimp ◽  
Bolaji Obadeyi ◽  
Grace Bissohong ◽  
Marie-Thérèse Obama ◽  
...  
Keyword(s):  
Neonatal Sepsis ◽  
C Reactive Protein ◽  
Low Resource Settings ◽  
Low Resource ◽  
Reactive Protein

Multi-Disciplinary COVID-19 Research Prioritization in Low-Resource Settings: The Ethiopia Model

2020 ◽  
Author(s):  
Afework Kassu ◽  
Getnet Yimer ◽  
Solomon Benor ◽  
Kassahun Tesfaye ◽  
Yifokre Tefera ◽  
...  
Keyword(s):  
Low Resource Settings ◽  
Low Resource ◽  
Research Prioritization
Sign in / Sign up

Export Citation Format

Share Document