scholarly journals Reflection on modern methods: years of life lost due to premature mortality—a versatile and comprehensive measure for monitoring non-communicable disease mortality

2019 ◽  
Vol 48 (4) ◽  
pp. 1367-1376 ◽  
Author(s):  
Ramon Martinez ◽  
Patricia Soliz ◽  
Roberta Caixeta ◽  
Pedro Ordunez
Keyword(s):  
Public Health ◽  
Communicable Disease ◽  
Premature Mortality ◽  
Years Of Life Lost ◽  
Loss Of Function ◽  
Country Level ◽  
Premature Deaths ◽  
Life Years ◽  
Disease Study ◽  
Non Communicable Disease

Abstract The analysis of causes impacting on premature mortality is an essential function of public health surveillance. Diverse methods have been used for accurately assessing and reporting the level and trends of premature mortality; however, many have important limitations, particularly in capturing actual early deaths. We argue that the framework of years of life lost (YLL), as conceptualized in disability-adjusted life-years (DALYs), is a robust and comprehensive measure of premature mortality. Global Burden of Disease study is systematically providing estimates of YLL; however, it is not widely adopted at country level, among other reasons because its conceptual and methodological bases seem to be not sufficiently known and understood. In this paper, we provide the concepts and the methodology of the YLL framework, including the selection of the loss of function that defines the time lost due to premature deaths, and detailed methods for calculating YLL metrics. We also illustrate how to use YLL to quantify the level and trends of premature non-communicable disease (NCD) mortality in the Americas. The tutorial style of the illustrative example is intended to educate the public health community and stimulate the use of YLL in disease prevention and control programmes at different levels.

Preventable premature deaths (PYLL) in Northern Dimension partnership countries 2003–13

2019 ◽  
Vol 29 (4) ◽  
pp. 626-630 ◽  
Author(s):  
Mikko A Vienonen ◽  
Pekka J Jousilahti ◽  
Karolina Mackiewicz ◽  
Rafael G Oganov ◽  
Vital M Pisaryk ◽  
...  
Keyword(s):  
Public Health ◽  
Geographical Area ◽  
Premature Mortality ◽  
Health Improvement ◽  
Malignant Neoplasms ◽  
Years Of Life Lost ◽  
Health In All Policies ◽  
Premature Deaths ◽  
Life Years ◽  
Country Differences

Abstract Background Objective was to measure preventable premature loss of life in countries from same geographical area but with considerable differences in social and economic development. By comparing inter-country differences and similarities in premature mortality, acceleration of health-in-all-policies is enhanced. Methods Preventable premature deaths were described by Potential Years of Life Lost (PYLL). Data consisted of death registers for 2003, 2009 and 2013. PYLL-rates were age-standardized by using standard OECD population from 1980 and expressed as sum of lost life years per 100 000 citizens. Results In Northern Dimension area, PYLL-rates had declined from 2003 to 2013. In 2013, worst PYLL-rate was in Belarus 9851 and best in Sweden 2511. PYLL-rates among men were twice as high as among women. Most premature losses (1023) were due to external causes. Malignant neoplasms came second (921) and vascular diseases third (816). Alcohol was also an important cause (270) and country differences were over 10-fold. Conclusions In ND-area, the overall development of public health has been good during 2003–13. Nevertheless, for all countries foci for public health improvement and learning from each other could be identified. Examining the health of populations in countries from relatively similar geographical area with different social history and cultures can provide them with evidence-based tools for health-in-all-policies to advocate health promotion and disease prevention. Gender differences due to preventable premature deaths are striking. The higher the national PYLL-rate, the bigger the PYLL-rate difference between men and women and the loss of human capital.

Forecasting the extent of future public health challenges using the Scottish Burden of Disease study

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
G M A Wyper ◽  
E Fletcher ◽  
I Grant ◽  
G McCartney ◽  
D L Stockton
Keyword(s):  
Public Health ◽  
Population Health ◽  
Burden Of Disease ◽  
Years Of Life Lost ◽  
Ageing Population ◽  
Health Trends ◽  
Life Years ◽  
The Future ◽  
Public Health Challenges ◽  
Disease Study

Abstract Background Over the next 25 years in Scotland there is expected to be negative natural change in population growth in a rapidly ageing population. Recent evidence has highlighted the slowing of life expectancy gains and worsening trends in self-assessed general health. We have adapted the Scottish Burden of Disease study to forecast how demographic and health trends will shape future public health challenges. This is important in order to inform policy, service and workforce planning to meet anticipated needs. Methods For a baseline period of 2014-16 Disability-Adjusted Life Years (DALYs) were estimated for 132 causes of burden using routine data sources and patient-level record linkage techniques. Disability weights and disease models used to calculate Years Lived with Disability (YLD) were largely based on those from the Global Burden of Disease study, with life tables used to facilitate calculations of Years of Life Lost (YLL). The leading 20 causes were identified and trends in the occurrence of morbidity and mortality are currently being estimated up until 2019, and forecast to 2040, using age-period-cohort modelling. Crude and age-standardised rates will be used to monitor changes due to demography and exposure to the wider social determinants of health. Results In 2014-16, the leading causes of burden were ischaemic heart disease, neck and low back pain, depression, lung cancer and cerebrovascular disease. The leading 20 causes represented 68% of all-cause DALYs with ill-health and disability causing almost half of the burden. Conclusions Insights of the future trajectory of population health equip us with strong evidence to influence the need for a strong policy response on prevention. Estimates of the future occurrence of morbidities can be embedded in planning to ensure that services and the care workforce are proportionately designed to meet the increasing needs of a vulnerable ageing population. Key messages The most recent assessment highlighted that non-fatal and fatal health states approximately contribute equally to the overall disease burden in Scotland. Evidencing how future demographic and population health trends interact allows us to ensure that policy responses, care services and the care workforce can be designed based on anticipated needs.

scholarly journals Assessment of premature mortality for noncommunicable diseases

2020 ◽  
Vol 73 (2) ◽  
Author(s):  
Plinio Tadeu Istilli ◽  
Carla Regina de Souza Teixeira ◽  
Maria Lúcia Zanetti ◽  
Rafael Aparecido Dias Lima ◽  
Marta Cristiane Alves Pereira ◽  
...  
Keyword(s):  
Public Health ◽  
Cardiovascular Disease ◽  
Ecological Study ◽  
Premature Mortality ◽  
Noncommunicable Diseases ◽  
Secondary Source ◽  
Years Of Life Lost ◽  
Health Prevention ◽  
Premature Deaths ◽  
Promotion Policies

ABSTRACT Objectives: to analyze premature mortality and Potential Years of Life Lost by noncommunicable diseases in a city in the countryside of São Paulo from 2010 to 2014. Methods: ecological study of temporal tendency, using secondary source. For analysis, the premature mortality coefficient and the Potential Years of Life Lost indicator were used. Results: males had the highest premature mortality rate due to cardiovascular disease, with 213.04 deaths per 100 thousand inhabitants, followed by neoplasms, with 188.44. In women, there was an inversion with 134.22 deaths from cancer and 110.71 deaths from cardiovascular disease. Regarding Potential Years of Life Lost, males had an average of 12.19 years lost by death and females of 13.45 years lost. Conclusions: the results reinforce the need to increase public health prevention and promotion policies to reduce premature deaths, especially among men.

scholarly journals Burden of injuries in Nepal, 1990–2017: findings from the Global Burden of Disease Study 2017

2020 ◽  
Vol 26 (Supp 1) ◽  
pp. i57-i66 ◽  
Author(s):  
Puspa Raj Pant ◽  
Amrit Banstola ◽  
Santosh Bhatta ◽  
Julie A Mytton ◽  
Dilaram Acharya ◽  
...  
Keyword(s):  
Public Health ◽  
Low Income ◽  
Burden Of Disease ◽  
Local Governments ◽  
Global Burden Of Disease ◽  
Global Burden ◽  
Years Of Life Lost ◽  
Life Years ◽  
Self Harm ◽  
Disease Study

BackgroundNepal is a low-income country undergoing rapid political, economic and social development. To date, there has been little evidence published on the burden of injuries during this period of transition.MethodsThe Global Burden of Disease Study (GBD) is a comprehensive measurement of population health outcomes in terms of morbidity and mortality. We analysed the GBD 2017 estimates for deaths, years of life lost, years lived with disability, incidence and disability-adjusted life years (DALYs) from injuries to ascertain the burden of injuries in Nepal from 1990 to 2017.ResultsThere were 16 831 (95% uncertainty interval 13 323 to 20 579) deaths caused by injuries (9.21% of all-cause deaths (7.45% to 11.25%)) in 2017 while the proportion of deaths from injuries was 6.31% in 1990. Overall, the injury-specific age-standardised mortality rate declined from 88.91 (71.54 to 105.31) per 100 000 in 1990 to 70.25 (56.75 to 85.11) per 100 000 in 2017. In 2017, 4.11% (2.47% to 6.10%) of all deaths in Nepal were attributed to transport injuries, 3.54% (2.86% to 4.08%) were attributed to unintentional injuries and 1.55% (1.16% to 1.85%) were attributed to self-harm and interpersonal violence. From 1990 to 2017, road injuries, falls and self-harm all rose in rank for all causes of death.ConclusionsThe increase in injury-related deaths and DALYs in Nepal between 1990 and 2017 indicates the need for further research and prevention interventions. Injuries remain an important public health burden in Nepal with the magnitude and trend of burden varying over time by cause-specific, sex and age group. Findings from this study may be used by the federal, provincial and local governments in Nepal to prioritise injury prevention as a public health agenda and as evidence for country-specific interventions.

scholarly journals What is Communicable? Unaccounted Injuries and “Catching” Diabetes in an Illegible Epidemic

2019 ◽  
Vol 34 (4) ◽  
Author(s):  
Amy Moran-Thomas
Keyword(s):  
Public Health ◽  
Infectious Disease ◽  
Disease Transmission ◽  
Communicable Disease ◽  
Treatment Access ◽  
Infectious Disease Transmission ◽  
The World ◽  
Historically Situated ◽  
Over Time ◽  
Non Communicable Disease

Long-accepted models of causality cast diseases into the binary of either “contagious” or “non-communicable,” typically with institutional resources focused primarily on interrupting infectious disease transmission. But in southern Belize, as in much of the world today, epidemic diabetes has become a leading cause of death and a notorious contributor to organ failure and amputated limbs. This ethnographic essay follows caregivers’ and families’ work to survive in-between public health categories, and asks what responses a bifurcated model of infectious versus non-communicable disease structures or incapacitates in practice. It proposes an alternative focus on diabetes as a “para-communicable” condition—materially transmitted as bodies and ecologies intimately shape each other over time, with unequal and compounding effects for historically situated groups of people. The article closes by querying how communicability relates to community, and why it matters to reframe narratives about contributing causalities in relation to struggles for treatment access.

scholarly journals The non-fatal burden of cancer in Belgium, 2004–2018

2021 ◽  
Author(s):  
Vanessa Gorasso ◽  
Geert Silversmit ◽  
Marc Arbyn ◽  
Astrid Cornez ◽  
Robby De Pauw ◽  
...  
Keyword(s):  
Skin Cancer ◽  
Burden Of Disease ◽  
Quality Data ◽  
Years Of Life Lost ◽  
Non Melanoma Skin Cancer ◽  
Life Years ◽  
National Burden ◽  
Disease Study ◽  
The Impact ◽  
Melanoma Skin

Abstract Background The importance of assessing and monitoring the health status of a population has grown in the last decades. Consistent and high quality data on the morbidity and mortality impact of a disease represent the key element for this assessment. Being increasingly used in global and national burden of diseases (BoD) studies, the Disability-Adjusted Life Year (DALY) is an indicator that combines healthy life years lost due to living with disease (Years Lived with Disability; YLD) and due to dying prematurely (Years of Life Lost; YLL). As a step towards a comprehensive national burden of disease study, this study aims to estimate the non-fatal burden of cancer in Belgium using national data. Methods We estimated the Belgian cancer burden from 2004 to 2018 in terms of YLD, using national population-based cancer registry data and international disease models. We developed a microsimulation model to translate incidence- into prevalence-based estimates, and used expert elicitation to integrate the long-term impact of increased disability due to surgical treatment. Results The age-standardized non-fatal burden of cancer increased from 2004 to 2018 by 6% and 2% respectively for incidence- and prevalence-based YLDs. In 2018, in Belgium, breast cancer had the highest morbidity impact among women, followed by colorectal and non-melanoma skin cancer. Among men, prostate cancer had the highest morbidity impact, followed by colorectal and non-melanoma skin cancer. Between 2004 and 2018, non-melanoma skin cancer significantly increased for both sexes in terms of age-standardized incidence-based YLD per 100,000, from 48 to 107 for men and from 15 to 37 for women. Important decreases were seen for colorectal cancer for both sexes in terms of age-standardized incidence-based YLD per 100,000, from 104 to 85 for men and from 52 to 46 for women. Conclusions Breast and prostate cancers represent the greatest proportion of cancer morbidity, while for both sexes the morbidity burden of skin cancer has shown an important increase from 2004 onwards. Integrating the current study in the Belgian national burden of disease study will allow monitoring of the burden of cancer over time, highlighting new trends and assessing the impact of public health policies.

scholarly journals Burden of Multiple Sclerosis in Eastern Mediterranean Region (1990-2016): Findings From the 2016 Global Burden of Disease Study

2019 ◽  
Author(s):  
Mohammad Ali Sahraian ◽  
Pouria Heydarpour ◽  
Maziar Moradi-Lakeh ◽  
Sharareh Eskandarieh ◽  
Seyed-Mohammad Fereshtehnejad ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Mediterranean Region ◽  
Eastern Mediterranean ◽  
Eastern Mediterranean Region ◽  
Years Of Life Lost ◽  
Effective Interventions ◽  
Disability Adjusted Life ◽  
Life Years ◽  
Disease Study ◽  
Years Lived With Disability

AbstractBackgroundMultiple sclerosis (MS) is among the leading causes of disability in Young Adults worldwide. Current estimates of MS burden in Eastern Mediterranean Region (EMR) are necessary for planning effective interventions .To estimate Prevalence, incidence, mortality, years lived with disability (YLDs), years of life lost (YLLs) and disability-adjusted life-years (DALYs) in EMR by country age, and sex from 1990 to 2016.MethodsWe estimated regional and country-specific prevalence, incidence, mortality, DALYs, YLLs, and YLDs for MS. DALYs were computed as the sum of YLDs and YLLs.ResultsTotal DALYs in EMR countries was 12,810 in 1990 for males and increased to 36,391 in 2016 and from 18,962 to 53,851 for females. Lowest DALYs in both sexes were observed in Somalia (248) while the highest were in Iran (26,394). YLDs in males increased from 6,511 in 1990 to 19,515 in 2016, and in females from 12,247 to 33,937. The highest age-standardized prevalence, incidence, YLDs and DALYs were in Iran (72.11, 2.49, 18.03, and 32.5, respectively).ConclusionsOur findings provide valuable information to guide the development and implementation of measures to address the rising burden of MS and it consequences in the EMR countries.

scholarly journals The Empowerment of Integrated Development Post of Non-Communicable Diseases in Efforts to Prevent and Control Non- Communicable Diseases

2016 ◽  
Vol 5 (3) ◽  
pp. 294
Author(s):  
Yandrizal Yandrizal ◽  
Rizanda Machmud ◽  
Melinda Noer ◽  
Hardisman Hardisman ◽  
Afrizal Afrizal ◽  
...  
Keyword(s):  
Public Health ◽  
Infectious Disease ◽  
Early Detection ◽  
Communicable Disease ◽  
Communicable Diseases ◽  
Combination Method ◽  
Integrated Development ◽  
Non Communicable Diseases ◽  
And Control ◽  
Non Communicable Disease

Non-Communicable disease has already been the main cause of death in many countries, as many as 57 million death in the world in 2008, 36 million (63 percent) is because of un-infectious disease, specifically heart illness, diabetes, cancer, and chronic respiratory diseases. Prevention and controlling efforts of un-infectious diseases developing in Indonesia is non-communicable disease integrated development post (Pospindu PTM). This research used combination method approach with exploratory design. Exploratory design with sequential procedure used combination consecutively, the first is qualitative and the second is quantitative method. Public Health Center formed Posbindu PTM has not disseminate yet to all stakeholders. Posbindu PTM members felt benefit by following this activity. Some of them did not know follow the activity because of unknown about it. There was  connection between coming behavior to Posbindu PTM to preventing behavior of non-communicable disease.Percentage for high blood pressure risk indicated 20-25 percent from all visitors. Formulation of its policy implementation started with stakeholder analysis; head of sub district, head of urban village, head of health department in regency/city, head of public health service, head of neighborhood Association, and the head of family welfare development.  Analysis of perception, power and authority found that every stakeholder had authority to manage the member directly or indirectly. It was not implemented because of the lack knowledge of stakeholders about the Posbindu PTM function.They would play a role after knowing the aim and advantage of the post by motivate the people to do early detection, prevention and control the non-communicable disease. The members were given wide knowledge about  early detection, preventing  and control the un-infectious disease, measuring and checking up their healthy continuously so that keep feeling the advantage of coming to the post.

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