scholarly journals Preferential location of sex chromosomes, their aneuploidy in human sperm, and their role in determining sex chromosome aneuploidy in embryos after ICSI

2002 ◽  
Vol 17 (2) ◽  
pp. 320-324 ◽  
Author(s):  
M. Sbracia
Keyword(s):  
Sex Chromosomes ◽  
Sex Chromosome ◽  
Human Sperm ◽  
Sex Chromosome Aneuploidy ◽  
Chromosome Aneuploidy ◽  
Preferential Location

scholarly journals Increased number of sex chromosomes affects height in a nonlinear fashion: A study of 305 patients with sex chromosome aneuploidy

2010 ◽  
Vol 152A (5) ◽  
pp. 1206-1212 ◽  
Author(s):  
Anne Marie Ottesen ◽  
Lise Aksglaede ◽  
Inger Garn ◽  
Nicole Tartaglia ◽  
Flora Tassone ◽  
...  
Keyword(s):  
Sex Chromosomes ◽  
Sex Chromosome ◽  
Sex Chromosome Aneuploidy ◽  
Chromosome Aneuploidy ◽  
Nonlinear Fashion

scholarly journals DNA methylation-based sex classifier to predict sex and identify sex chromosome aneuploidy

2020 ◽  
Author(s):  
Yucheng Wang ◽  
Eilis Hannon ◽  
Olivia A Grant ◽  
Tyler J Gorrie-Stone ◽  
Meena Kumari ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Sex Chromosome ◽  
Klinefelter Syndrome ◽  
Association Studies ◽  
Gene Expression Omnibus ◽  
Sex Chromosome Aneuploidy ◽  
Chromosome Aneuploidy ◽  
Wide Range ◽  
Almost All ◽  
Methylation Patterns

AbstractSex is an important covariate of epigenome-wide association studies due to its strong influence on DNA methylation patterns across numerous genomic positions. Nevertheless, many samples on the Gene Expression Omnibus (GEO) frequently lack a sex annotation or are incorrectly labelled. Considering the influence that sex imposes on DNA methylation patterns, it is necessary to ensure that methods for filtering poor samples and checking of sex assignment are accurate and widely applicable. In this paper, we presented a novel method to predict sex using only DNA methylation density signals, which can be readily applied to almost all DNA methylation datasets of different formats (raw IDATs or text files with only density signals) uploaded to GEO. We identified 4345 significantly (p < 0.01) sex-associated CpG sites present on both 450K and EPIC arrays, and constructed a sex classifier based on the two first components of PCAs from the two sex chromosomes. The proposed method is constructed using whole blood samples and exhibits good performance across a wide range of tissues. We further demonstrated that our method can be used to identify samples with sex chromosome aneuploidy, this function is validated by five Turner syndrome cases and one Klinefelter syndrome case. The proposed method has been integrated into the wateRmelon Bioconductor package.

Sex Chromosome Aneuploidy Alters the Relationship Between Cortical Anatomy and Cognitive Functioning

2020 ◽  
Vol 87 (9) ◽  
pp. S336
Author(s):  
Allysa Warling ◽  
Kathleen Wilson ◽  
Ethan Whitman ◽  
Siyuan Liu ◽  
Liv S. Clasen ◽  
...  
Keyword(s):  
Cognitive Functioning ◽  
Sex Chromosome ◽  
Sex Chromosome Aneuploidy ◽  
Chromosome Aneuploidy ◽  
The Relationship

Screening, prenatal diagnosis, and prenatal decision for sex chromosome aneuploidy

2019 ◽  
Vol 19 (6) ◽  
pp. 537-542 ◽  
Author(s):  
Yong Xu ◽  
Liyuan Chen ◽  
Yang Liu ◽  
Ying Hao ◽  
Zhiyong Xu ◽  
...  
Keyword(s):  
Prenatal Diagnosis ◽  
Sex Chromosome ◽  
Sex Chromosome Aneuploidy ◽  
Chromosome Aneuploidy
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