scholarly journals Infectious processes: an infrequent cause of first trimester spontaneous abortions

1996 ◽  
Vol 11 (3) ◽  
pp. 668-672 ◽  
Author(s):  
J. L. Simpson ◽  
J. L. Mills ◽  
H. Kim ◽  
L. B. Holmes ◽  
J. Lee ◽  
...  
Keyword(s):  
First Trimester ◽  
Spontaneous Abortions

First Trimester Hemoglobin A1 and Risk for Major Malformation and Spontaneous Abortion

2021 ◽  
pp. 13-19
Author(s):  
Rachel Blake ◽  
Chloe Zera
Keyword(s):  
Spontaneous Abortion ◽  
Clinical Case ◽  
First Trimester ◽  
Spontaneous Abortions ◽  
Major Malformation ◽  
Fetal Malformations ◽  
Study Population ◽  
Hemoglobin A1 ◽  
Location Study

This chapter summarizes a landmark study on the association of first trimester hemoglobin A1 values with risk for spontaneous abortions and major fetal malformations during pregnancy in women with pregestational diabetes. Is there a correlation between glycemic control during the first trimester and risk for spontaneous abortion and major malformations? Starting with this question, it describes the basics of the study, including study location, study population, amount of patients, study design, follow-up, endpoints, results, and criticism and limitations. The chapter briefly reviews other relevant studies and information, discusses implications, and concludes with a relevant clinical case.

Pregnancy outcome in chronic myeloid leukemia patients on imatinib therapy.

2013 ◽  
Vol 31 (15_suppl) ◽  
pp. 7114-7114
Author(s):  
Swati Dasgupta ◽  
Ashis Mukhopadhyay ◽  
Ujjal Kanti Ray ◽  
Firoj Hossain Gharami ◽  
Chinmay Kumar Basu ◽  
...  
Keyword(s):  
Congenital Anomaly ◽  
Chronic Myeloid Leukemia ◽  
Myeloid Leukemia ◽  
Unplanned Pregnancy ◽  
First Trimester ◽  
Imatinib Therapy ◽  
Spontaneous Abortions ◽  
Male And Female ◽  
Increased Risk ◽  
Male Patients

7114 Background: Now that imatinib is being used to treat thousands of chronic myeloid leukemia (CML) patients for more than 10 year it is highly probable that many patients will get pregnant during its use. Company warns against any such use. But the fact remains that there is need for planned pregnancies in indicated cases. So we selected few cases both male and female for such pregnancies by interrupting treatment and following the pregnancy closely. Their outcome was studied so that we have an idea about what best could be suggested in such instance. Methods: From November 2002 to May 2010, 634 patients with CML in any stage of the disease were treated with imatinib at our tertiary cancer research institute. We selected 22 (12 females and 10 males) cases of pregnancies by interrupting treatment. We reported 9 accidental pregnancies and 13 planned pregnancies involving 22 patients who or their wives conceived while receiving imatinib for the treatment of CML. Results: Among 22 pregnancies there were 3 spontaneous abortions and 4 elective abortions. In case of 7 female patients, 3 and 4 were male and female babies respectably and in case of six male patients 4 and 4 were male and female babies. Two babies were with congenital anomaly such as one Hypospandium and one Mild-Hydrocephalus (in case of unplanned pregnancies and imatinib exposure during the first trimester of organogenesis). Conclusions: In conclusion, exposure to Imatinib during pregnancy might result in an increased risk of serious fetal abnormalities or spontaneous abortions. Women of childbearing potential should use adequate contraception while using Imatinib. We can suggest that planned pregnancy during therapy should be encouraged but imatinib therapy in unplanned pregnancy can cause spontaneous abortion or minor congenital anomaly.

Cytogenetic analysis and fetal heart activity of spontaneous abortions in the first trimester

2002 ◽  
Vol 78 ◽  
pp. S250
Author(s):  
Kwang Moon Yang ◽  
Jin Hyun Jun ◽  
In Ok Song ◽  
Jin Yeong Kim ◽  
Jong Young Jun ◽  
...  
Keyword(s):  
Cytogenetic Analysis ◽  
Fetal Heart ◽  
First Trimester ◽  
Spontaneous Abortions ◽  
Heart Activity

Clinical indicators of aneuploidy in first trimester spontaneous abortions

2011 ◽  
Vol 96 (3) ◽  
pp. S219
Author(s):  
A.E. Batcheller ◽  
S. Deighton-Collins ◽  
J. Espinoza Dorado ◽  
L. Wolf ◽  
B. Miller ◽  
...  
Keyword(s):  
First Trimester ◽  
Spontaneous Abortions ◽  
Clinical Indicators

Prevalence of developmental and inflammatory lesions in nonmolar first-trimester spontaneous abortions

1999 ◽  
Vol 30 (1) ◽  
pp. 93-100 ◽  
Author(s):  
Raymond W Redline ◽  
Michael Zaragoza ◽  
Terry Hassold
Keyword(s):  
First Trimester ◽  
Spontaneous Abortions ◽  
Inflammatory Lesions

scholarly journals Chromosomal abnormalities in recurrent spontaneous abortions: A retrospective study

2020 ◽  
Author(s):  
Inusha Panigrahi ◽  
Mohd. Shariq ◽  
Ravi Thakur ◽  
Subhas Saha ◽  
Gurjit Kaur
Keyword(s):  
Chromosomal Rearrangement ◽  
Chromosomal Abnormalities ◽  
Chromosomal Rearrangements ◽  
First Trimester ◽  
Median Number ◽  
Chromosomal Anomalies ◽  
Spontaneous Abortions ◽  
Reciprocal Translocations ◽  
Recurrent Spontaneous Abortions ◽  
Complex Chromosomal Rearrangement

Purpose: Evaluation of recurrent spontaneous abortions (RSA) can be challenging for a Obstetrician. In case of early first trimester abortions, chromosomal abnormalities can be identified as an important cause. We analysed the RSA cases followed up and diagnosed in the Genetic Clinic or Genetic Lab of 2 hospitals in the region. Methods: Those couples with 3 or more spontaneous abortions were included in the analysis. Karyotyping was one using standard protocol with G-banding and reporting as per ISCN guidelines. Results: Of 97 RSA couples, 20 showed chromosomal abnormalities, and 15 of these had balanced chromosomal rearrangements. The age ranged from 22 years to 37 years, and the median number of abortions was 4. Complex chromosomal rearrangement was seen in 2 couples, in one partner. The spectrum of chromosomal anomalies in couples with RSA is discussed here. Conclusions: Frequency of chromosomal abnormalities in RSA was higher in present study compared to previous studies. Reciprocal translocations were commonest abnormality.

Laparoscopic metroplasty for bicornuate uterus – A case report

2021 ◽  
Vol 8 (2) ◽  
pp. 279-281
Author(s):  
Lakshmi Subburaj ◽  
K Rajkumar
Keyword(s):  
Case Report ◽  
First Trimester ◽  
Mullerian Duct ◽  
Spontaneous Abortions ◽  
Bicornuate Uterus ◽  
Müllerian Duct ◽  
Recurrent Spontaneous Abortions ◽  
Fertility Status ◽  
Müllerian Duct Anomalies ◽  
Müllerian Duct Anomaly

Bicornuate uterus is a type of mullerian duct anomaly which is responsible for recurrent spontaneous first trimester abortions. They are best managed surgically using Strassman’s metroplasty. We present a case of recurrent spontaneous abortions which was diagnosed as bicornuate uterus. We performed a laparoscopic metroplasty which was successful and did not encounter complications like adhesions or hemorrhage. The advantages of laparoscopic metroplasty outweighs the challenges in restoring fertility status to women with mullerian duct anomalies.

Analyses of 95 first-trimester spontaneous abortions by chorionic villus sampling and karyotype

1992 ◽  
Vol 9 (5) ◽  
pp. 458-461 ◽  
Author(s):  
Charles M. Strom ◽  
Norman Ginsberg ◽  
Michael Applebaum ◽  
Nader Bozorgi ◽  
Melody White ◽  
...  
Keyword(s):  
Chorionic Villus ◽  
First Trimester ◽  
Chorionic Villus Sampling ◽  
Spontaneous Abortions
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