scholarly journals Human Endogenous Retrovirus-K18 Superantigen Expression and Human Herpesvirus-6 and Human Herpesvirus-7 Viral Loads in Chronic Fatigue Patients

2013 ◽  
Vol 56 (10) ◽  
pp. 1394-1400 ◽  
Author(s):  
Brendan Oakes ◽  
Matthias Hoagland-Henefield ◽  
Anthony L. Komaroff ◽  
Jessica L. Erickson ◽  
Brigitte T. Huber
Keyword(s):  
Human Herpesvirus ◽  
Chronic Fatigue ◽  
Endogenous Retrovirus ◽  
Human Endogenous Retrovirus ◽  
Human Herpesvirus 6 ◽  
Viral Loads ◽  
Herpesvirus 6

Antibody Responses to Epstein-Barr Virus, Human Herpesvirus 6 and Human Herpesvirus 7 in Patients with Chronic Fatigue Syndrome

Intervirology ◽  
1995 ◽  
Vol 38 (5) ◽  
pp. 269-273 ◽  
Author(s):  
Takeshi Sairenji ◽  
Koichi Yamanishi ◽  
Yoichi Tachibana ◽  
Giuseppe Bertoni ◽  
Takeshi Kurata
Keyword(s):  
Chronic Fatigue Syndrome ◽  
Epstein Barr Virus ◽  
Human Herpesvirus ◽  
Chronic Fatigue ◽  
Antibody Responses ◽  
Human Herpesvirus 6 ◽  
Barr Virus ◽  
Fatigue Syndrome ◽  
Herpesvirus 6 ◽  
Epstein Barr

scholarly journals Estimating the Risk of Human Herpesvirus 6 and Cytomegalovirus Transmission to Ugandan Infants from Viral Shedding in Saliva by Household Contacts

Viruses ◽  
2020 ◽  
Vol 12 (2) ◽  
pp. 171 ◽  
Author(s):  
Bryan T. Mayer ◽  
Elizabeth M. Krantz ◽  
Anna Wald ◽  
Lawrence Corey ◽  
Corey Casper ◽  
...  
Keyword(s):  
Dose Response ◽  
Human Herpesvirus ◽  
Transmission Risk ◽  
Birth Cohort Study ◽  
Response Relationship ◽  
Human Herpesvirus 6 ◽  
Dose Response Relationship ◽  
Viral Loads ◽  
Viral Shedding ◽  
Herpesvirus 6

Human herpesvirus 6 (HHV-6) and cytomegalovirus (CMV) infections are common in early childhood. In a prospective Ugandan birth cohort study, most infants acquired HHV-6 (24/31; 77%) and CMV (20/30; 67%) during follow-up. To assess the transmission risk, we modeled a dose–response relationship between infant HHV-6 and CMV infections and weekly oral viral shedding by mothers and all other (“secondary”) children in the home. Oral viral loads that were shed by mothers and secondary children were significantly associated with HHV-6 but not CMV transmission. While secondary children had higher and more frequent HHV-6 shedding than their mothers, they had a lower per-exposure transmission risk, suggesting that transmission to maternal contacts may be more efficient. HHV-6 transmission was relatively inefficient, occurring after <25% of all weekly exposures. Although HHV-6 transmission often occurs following repeated, low dose exposures, we found a non-linear dose–response relationship in which infection risk markedly increases when exposures reached a threshold of > 5 log10 DNA copies/mL. The lack of association between oral CMV shedding and transmission is consistent with breastfeeding being the dominant route of infant infection for that virus. These affirm saliva as the route of HHV-6 transmission and provide benchmarks for developing strategies to reduce the risk of infection and its related morbidity.

scholarly journals Cytomegalovirus, Epstein‐Barr virus, and human herpesvirus‐6 infections in patients with myalgic еncephalomyelitis/chronic fatigue syndrome

2020 ◽  
Vol 92 (12) ◽  
pp. 3682-3688 ◽  
Author(s):  
Evelina Shikova ◽  
Valentina Reshkova ◽  
Аntoniya Kumanova ◽  
Sevdalina Raleva ◽  
Dora Alexandrova ◽  
...  
Keyword(s):  
Chronic Fatigue Syndrome ◽  
Epstein Barr Virus ◽  
Human Herpesvirus ◽  
Chronic Fatigue ◽  
Human Herpesvirus 6 ◽  
Barr Virus ◽  
Fatigue Syndrome ◽  
Herpesvirus 6 ◽  
Epstein Barr

Human herpesvirus 6

1997 ◽  
Vol 1 (1) ◽  
pp. 1-17 ◽  
Author(s):  
Stephen Dewhurst ◽  
David Skrincosky ◽  
Nanette van Loon
Keyword(s):  
Neurological Disorders ◽  
Human Herpesvirus ◽  
Chronic Fatigue ◽  
Human Herpesvirus 6 ◽  
Common Cause ◽  
Exanthem Subitum ◽  
Acquired Immunodeficiency ◽  
Herpesvirus 6 ◽  
Almost All ◽  
Immunodeficiency Syndrome

Human herpesvirus 6 (HHV-6) is a T-lymphotropic herpesvirus, which infects almost all children by the age of two years and persists lifelong. Two distinct variants of HHV-6, HHV-6A and HHV-6B, have been described, and the latter has been shown to be a common cause of acute febrile illnesses in young children, including exanthem subitum (roseola). HHV-6 has also been associated with a number of neurological disorders, including encephalitis and seizures, and the virus has been postulated to play a role in acquired immunodeficiency syndrome (AIDS), multiple sclerosis (MS) and chronic fatigue immunodeficiency syndrome (CFIDS). This review provides a critical summary of research conducted on HHV-6.

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