Is inherited human herpesvirus 6 the perpetrator behind some cases of chronic fatigue syndrome?

2014 ◽  
Vol 9 (4) ◽  
pp. 433-436
Author(s):  
Emily Lum ◽  
Maria M Medveczky ◽  
Peter G Medveczky
Keyword(s):  
Chronic Fatigue Syndrome ◽  
Human Herpesvirus ◽  
Chronic Fatigue ◽  
Human Herpesvirus 6 ◽  
Fatigue Syndrome ◽  
Herpesvirus 6

Antibody Responses to Epstein-Barr Virus, Human Herpesvirus 6 and Human Herpesvirus 7 in Patients with Chronic Fatigue Syndrome

Intervirology ◽  
1995 ◽  
Vol 38 (5) ◽  
pp. 269-273 ◽  
Author(s):  
Takeshi Sairenji ◽  
Koichi Yamanishi ◽  
Yoichi Tachibana ◽  
Giuseppe Bertoni ◽  
Takeshi Kurata
Keyword(s):  
Chronic Fatigue Syndrome ◽  
Epstein Barr Virus ◽  
Human Herpesvirus ◽  
Chronic Fatigue ◽  
Antibody Responses ◽  
Human Herpesvirus 6 ◽  
Barr Virus ◽  
Fatigue Syndrome ◽  
Herpesvirus 6 ◽  
Epstein Barr

scholarly journals Cytomegalovirus, Epstein‐Barr virus, and human herpesvirus‐6 infections in patients with myalgic еncephalomyelitis/chronic fatigue syndrome

2020 ◽  
Vol 92 (12) ◽  
pp. 3682-3688 ◽  
Author(s):  
Evelina Shikova ◽  
Valentina Reshkova ◽  
Аntoniya Kumanova ◽  
Sevdalina Raleva ◽  
Dora Alexandrova ◽  
...  
Keyword(s):  
Chronic Fatigue Syndrome ◽  
Epstein Barr Virus ◽  
Human Herpesvirus ◽  
Chronic Fatigue ◽  
Human Herpesvirus 6 ◽  
Barr Virus ◽  
Fatigue Syndrome ◽  
Herpesvirus 6 ◽  
Epstein Barr

scholarly journals Human herpesvirus 6 infection and risk of Chronic fatigue syndrome: a systematic review and meta-analysis

Intervirology ◽  
2021 ◽  
Author(s):  
Sayed-Hamidreza Mozhgani ◽  
Farid Rajabi ◽  
Mohsen Qurbani ◽  
Yousef Erfani ◽  
Somayeh Yaslianifard ◽  
...  
Keyword(s):  
Systematic Review ◽  
Chronic Fatigue Syndrome ◽  
Meta Analysis ◽  
Human Herpesvirus ◽  
Chronic Fatigue ◽  
Human Herpesvirus 6 ◽  
Fatigue Syndrome ◽  
Herpesvirus 6

scholarly journals Human Herpesvirus 6 and Chronic Fatigue Syndrome

1993 ◽  
Vol 4 (4) ◽  
pp. 199-202 ◽  
Author(s):  
Daniel Eymard ◽  
François Lebel ◽  
Mark Miller ◽  
François Turgeon
Keyword(s):  
Chronic Fatigue Syndrome ◽  
Univariate Analysis ◽  
Human Herpesvirus ◽  
Chronic Fatigue ◽  
Human Herpesvirus 6 ◽  
Fatigue Syndrome ◽  
Significant Difference ◽  
Group A ◽  
Herpesvirus 6 ◽  
Group B

The cause of chronic fatigue syndrome (CFS) is still enigmatic. Using indirect immunofluorescence testing for measuring antibody against human herpesvirus 6 (HHV-6), this study investigated the association of CFS with infection by HHV-6. Seventeen patients (group A) fulfilling the Centers for Disease Control (CDC) definition for CFS were compared with eight patients (group B) with chronic fatigue but not meeting the CDC criteria. No significant difference was found between the two groups for 30 parameters including sex, age, exposure to children and serology for Epstein-Barr virus, cytomegalovirus, herpes simplex virus, and toxoplasma. Univariate analysis showed that patients in group A complained more frequently of a sore throat, headache and of recurrent type of fatigue. These three parameters are discriminant in identifying patients who will meet the CDC case definition of CFS. The titre of antibody against HHV-6 in group A (1:99) was significantly higher than in group B (1:15) (P=0.007). Elevated HHV-6 titres suggests that this virus could be a cofactor in the pathogenesis of CFS.

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