Effects of dietary saponins on fecal bile acids and neutral sterols, plasma lipids, and lipoprotein turnover in the pig

1980 ◽  
Vol 33 (4) ◽  
pp. 783-786 ◽  
Author(s):  
D L Topping ◽  
G B Storer ◽  
G D Calvert ◽  
R J Illman ◽  
D G Oakenfull ◽  
...  
Keyword(s):  
Bile Acids ◽  
Plasma Lipids ◽  
Fecal Bile Acids ◽  
Neutral Sterols

scholarly journals Effects of saponins on bile acids and plasma lipids in the rat

1979 ◽  
Vol 42 (2) ◽  
pp. 209-216 ◽  
Author(s):  
D. G. Oakenfull ◽  
Dorothy E. Fenwick ◽  
R. L. Hood ◽  
D. L. Topping ◽  
R. L. Illman ◽  
...  
Keyword(s):  
Bile Acids ◽  
Plasma Lipids ◽  
Plasma Lipid ◽  
High Cholesterol Diet ◽  
Cholesterol Diet ◽  
High Cholesterol ◽  
Faecal Excretion ◽  
Neutral Sterols ◽  
Low Cholesterol ◽  
Bile Acid Secretion

1. The effects of feeding isolated saponins on plasma lipid concentrations and on concentrations of biliary and faecal bile acids and neutral sterols were studied in the rat.2. The animals were given one of four diets, i.e. a standard low-cholesterol synthetic diet, the diet+10 g saponins/kg, the diet+10 g cholesterol/kg, the diet+10 g cholesterol+10 g saponins/kg.3. Saponins partially reversed the hypercholesterolaemia caused by the high-cholesterol diet and increased both the rate of bile acid secretion and the faecal excretion of bile acids and neutral sterols. The proportionate contribution of the primary bile acids (particularly chenodeoxycholic) to faecal excretion was also increased by saponins.4. The results are discussed in relation to the hypothesis that saponins act by inducing the adsorption of bile acids by dietary fibre.

scholarly journals Effects of an Insoluble Fraction of Soy Protein Versus Milk Protein on Plasma Lipids and Fecal Bile Acids in Men and Women with Hypercholesterolemia

2010 ◽  
Vol 4 (3) ◽  
pp. 211
Author(s):  
Kevin Carl Maki ◽  
Dustie N. Butteiger ◽  
Tia M. Rains ◽  
Matthew S. Reeves ◽  
Chuck Schasteen ◽  
...  
Keyword(s):  
Bile Acids ◽  
Soy Protein ◽  
Milk Protein ◽  
Plasma Lipids ◽  
Insoluble Fraction ◽  
Men And Women ◽  
Fecal Bile Acids ◽  
Protein Versus

Fecal Bile Acids and Neutral Sterols in Japanese with Large Bowel Carcinoma

Oncology ◽  
1983 ◽  
Vol 40 (4) ◽  
pp. 255-258 ◽  
Author(s):  
Nobuaki Kaibara ◽  
Toshiaki Sasaki ◽  
Masahide Ikeguchi ◽  
Shigemasa Koga ◽  
Shiro Ikawa
Keyword(s):  
Bile Acids ◽  
Large Bowel ◽  
Fecal Bile Acids ◽  
Neutral Sterols

scholarly journals Fecal bile acids and neutral sterols in patients with familial polyposis

Cancer ◽  
1976 ◽  
Vol 38 (4) ◽  
pp. 1694-1698 ◽  
Author(s):  
Bandaru S. Reddy ◽  
A. Mastromarino ◽  
Carol Gustafson ◽  
M. Lipkin ◽  
E. L. Wynder
Keyword(s):  
Bile Acids ◽  
Familial Polyposis ◽  
Fecal Bile Acids ◽  
Neutral Sterols

scholarly journals A trial of the effects of soya-bean flour and soya-bean saponins on plasma lipids, faecal bile acids and neutral sterols in hypercholesterolaemic men

1981 ◽  
Vol 45 (2) ◽  
pp. 277-281 ◽  
Author(s):  
G. D. Calvert ◽  
Lesley Blight ◽  
R. J. Illman ◽  
D. L. Topping ◽  
J. D. Potter
Keyword(s):  
Bile Acids ◽  
Plasma Lipids ◽  
Lipid Analysis ◽  
Plasma Cholesterol ◽  
Soya Bean ◽  
Plasma Lipoprotein ◽  
Double Blind ◽  
Bean Flour ◽  
Neutral Sterols ◽  
Double Blind Crossover Study

1. The hypothesis that soya-bean saponins, by binding bile salts in the gastrointestinal lumen, are responsible for some of the plasma-cholesterol-lowering effect of soya-bean preparations, was tested. In a double-blind crossover study 50 g soya-bean flour/d, containing either 22 or 4 g saponins/kg (adjusted by ethanol extraction) was incorporated in biscuits as a substitute for biscuits or bread into the diet of ten outpatient hypercholesterolaemic men over two consecutive 4-week study periods. The diet was monitored to ensure constancy, saponin-rich foods excluded, faeces collected for bile acid and neutral sterol analysis, and blood taken for plasma lipoprotein lipid analysis.2. Neither diet had any effect on cholesterol in any plasma lipoprotein fraction, on fasting plasma triglyceride, or on faecal bile acids and neutral sterols.3. These results suggested that soya-bean saponins are not responsible for the hypocholesterolaemic effect of soya-bean products.

Fecal bile acids and neutral sterols in rats with spontaneous colon cancer

1986 ◽  
Vol 37 (4) ◽  
pp. 629-632 ◽  
Author(s):  
Eijiro Hayashi ◽  
Yoshiki Amuro ◽  
Tomoichiro Endo ◽  
Hideo Yamamoto ◽  
Makoto Miyamoto ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Bile Acids ◽  
Fecal Bile Acids ◽  
Neutral Sterols

Diet, fecal bile acids, and neutral sterols in carcinoma of the colon

1979 ◽  
Vol 24 (10) ◽  
pp. 746-751 ◽  
Author(s):  
Morry Moskovitz ◽  
Colin White ◽  
Roy N. Barnett ◽  
Sydney Stevens ◽  
Edith Russell ◽  
...  
Keyword(s):  
Bile Acids ◽  
Carcinoma Of The Colon ◽  
Fecal Bile Acids ◽  
Neutral Sterols
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