Variations in Serum Free Thyroxine Concentration Within the Reference Range Predicts the Incidence of Metabolic Syndrome in Non-Obese Adults: A Cohort Study

Thyroid ◽  
2017 ◽  
Vol 27 (7) ◽  
pp. 886-893 ◽  
Author(s):  
Ladan Mehran ◽  
Atieh Amouzegar ◽  
Mahmood Bakhtiyari ◽  
Mohammad Ali Mansournia ◽  
Parnian Kheirkhah Rahimabad ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Cohort Study ◽  
Reference Range ◽  
Free Thyroxine ◽  
Obese Adults ◽  
Serum Free ◽  
Serum Free Thyroxine

scholarly journals Serum Free Thyroxine and Free Tri-Iodothyronine in Normal Children

1988 ◽  
Vol 25 (5) ◽  
pp. 536-539 ◽  
Author(s):  
J Butler ◽  
P Moore ◽  
G Mieli-Vergani ◽  
C Moniz
Keyword(s):  
Thyroid Hormone ◽  
Reference Range ◽  
Free Thyroxine ◽  
Normal Children ◽  
Serum Free ◽  
Upper Limit ◽  
Free Thyroid Hormone ◽  
The Mean ◽  
Mean Concentration ◽  
Serum Free Thyroxine

Serum free thyroxine (fT4) and free tri-iodothyronine (fT3) were measured in 138 normal school children, adolescents and their younger siblings, whose ages ranged from 3 months to 18 years. Mean fT4 concentration (16·8 pmol/L) was similar to the adult mean concentration of 17 pmol/L and all the values were within the adult reference range. At all ages the fT3 range was considerably higher than the adult reference range and the overall mean fT3 concentration (8·3 pmol/L) was at the upper limit of normal in adults. In subjects aged 13–18 years the mean fT4 concentration was higher and the mean fT3 concentration lower than in children aged 0–12 years. The reasons for these differences are not known, but the data obtained provide a useful guide to the interpretation of serum free thyroid hormone measurements in children.

Lower serum free thyroxine levels are associated with metabolic syndrome in a Chinese population

Metabolism ◽  
2005 ◽  
Vol 54 (11) ◽  
pp. 1524-1528 ◽  
Author(s):  
Shih-Yi Lin ◽  
Ya-Yu Wang ◽  
Pi-Haw Liu ◽  
Wen-An Lai ◽  
Wayne Huey-Herng Sheu
Keyword(s):  
Metabolic Syndrome ◽  
Chinese Population ◽  
Free Thyroxine ◽  
Lower Serum ◽  
Serum Free ◽  
Serum Free Thyroxine

Serum Free Thyroxine Concentration is Associated with Metabolic Syndrome in Euthyroid Subjects

Thyroid ◽  
2014 ◽  
Vol 24 (11) ◽  
pp. 1566-1574 ◽  
Author(s):  
Ladan Mehran ◽  
Atieh Amouzegar ◽  
Maryam Tohidi ◽  
Maryam Moayedi ◽  
Fereidoun Azizi
Keyword(s):  
Metabolic Syndrome ◽  
Free Thyroxine ◽  
Serum Free ◽  
Serum Free Thyroxine

Effects of Age and Health on the Euthyroid Reference Ranges for Serum Free Thyroxine and Free Triiodothyronine

1985 ◽  
Vol 24 (02) ◽  
pp. 57-65 ◽  
Author(s):  
J. E. M. Midgley ◽  
K. R. Gruner
Keyword(s):  
Lower Limit ◽  
Healthy Subjects ◽  
Thyroid Dysfunction ◽  
Reference Range ◽  
Free Thyroxine ◽  
Reference Ranges ◽  
Free Triiodothyronine ◽  
Serum Free ◽  
Young Subjects ◽  
Age Range

SummaryAge-related trends in serum free thyroxine (FT4) and free triiodothyronine (FT3) concentrations were measured in 7248 euthyroid subjects (age-range 3 months to 106 years). 5700 were patients referred to hospitals for investigation of suspected thyroid dysfunction, but who were diagnosed euthyroid. 1548 were healthy blood donors (age-range 18-63 years) with no indication of thyroid dysfunction. FT4 concentrations were little affected by the age, the sex or the state of health of the subjects in either group. Serum FT3 concentrations were significantly affected by both age and health factors. The upper limit of the euthyroid reference range for young subjects up to 15 years was about 20% higher (10.4 pmol/1) than for adult subjects older than 25 years (8.8 pmol/1). The change in the upper limits typical of young subjects to that typical of adults occurred steadily over the decade 15–25 years. After this age, little further change occurred, especially in healthy subjects. Additionally, the lower limit of the euthyroid range for FT3 was extended by the inclusion in the reference group of patients referred to hospitals. Compared with the lower limit of the FT3 range for healthy subjects (5 pmol/1), the corresponding limit for referred subjects (young or adult) was 3.5–3.8 pmol/1. Broadening of the FT3 reference range was probably brought about by a significant number of patients in the hospital-referred group with the “1OW-T3 syndrome” of mild non-thyroidal illness. Accordingly, FT3 was inferior to FT4 in the discrimination of hypothyroidism, as FT4 was unaffected by this phenomenon. Effects of age and non-thyroidal illness on serum FT3 concentrations require great care when selecting subjects for a laboratory euthyroid reference range typical of the routine workload. Constraints on the choice of subjects for FT4 reference ranges are less stringent.

Factors Affecting the Serum Free Thyroxine Levels in Hospitalized Chronic Geriatric Patients

1993 ◽  
Vol 41 (7) ◽  
pp. 742-746 ◽  
Author(s):  
Istvan Szabolcs ◽  
Christoph Ploenes ◽  
Mathias Beyer ◽  
Wolfdieter Bernard ◽  
Jorg Herrmann
Keyword(s):  
Geriatric Patients ◽  
Free Thyroxine ◽  
Factors Affecting ◽  
Serum Free ◽  
Serum Free Thyroxine

scholarly journals Serum Free Thyroxine and Triiodothyronine Concentrations in Subacute Thyroiditis

1980 ◽  
Vol 56 (11) ◽  
pp. 1527-1534
Author(s):  
Katsumi YOSHIDA ◽  
Toshiro SAKURADA ◽  
Nobuko KAISE ◽  
Kazuo KAISE ◽  
Hirofumi KITAOKA ◽  
...  
Keyword(s):  
Free Thyroxine ◽  
Subacute Thyroiditis ◽  
Serum Free ◽  
Serum Free Thyroxine

scholarly journals Serum free thyroxine levels are associated with the efficacy of weight reduction therapy in obese female patients

2016 ◽  
Vol 63 (3) ◽  
pp. 221-229 ◽  
Author(s):  
Koshi Hashimoto ◽  
Tetsuya Tagami ◽  
Hajime Yamakage ◽  
Kazuya Muranaka ◽  
Masashi Tanaka ◽  
...  
Keyword(s):  
Weight Reduction ◽  
Free Thyroxine ◽  
Serum Free ◽  
Female Patients ◽  
Obese Female ◽  
Serum Free Thyroxine
Sign in / Sign up

Export Citation Format

Share Document