Serum Free Thyroxine Concentration is Associated with Metabolic Syndrome in Euthyroid Subjects

Thyroid ◽  
2014 ◽  
Vol 24 (11) ◽  
pp. 1566-1574 ◽  
Author(s):  
Ladan Mehran ◽  
Atieh Amouzegar ◽  
Maryam Tohidi ◽  
Maryam Moayedi ◽  
Fereidoun Azizi
Keyword(s):  
Metabolic Syndrome ◽  
Free Thyroxine ◽  
Serum Free ◽  
Serum Free Thyroxine

Variations in Serum Free Thyroxine Concentration Within the Reference Range Predicts the Incidence of Metabolic Syndrome in Non-Obese Adults: A Cohort Study

Thyroid ◽  
2017 ◽  
Vol 27 (7) ◽  
pp. 886-893 ◽  
Author(s):  
Ladan Mehran ◽  
Atieh Amouzegar ◽  
Mahmood Bakhtiyari ◽  
Mohammad Ali Mansournia ◽  
Parnian Kheirkhah Rahimabad ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Cohort Study ◽  
Reference Range ◽  
Free Thyroxine ◽  
Obese Adults ◽  
Serum Free ◽  
Serum Free Thyroxine

Lower serum free thyroxine levels are associated with metabolic syndrome in a Chinese population

Metabolism ◽  
2005 ◽  
Vol 54 (11) ◽  
pp. 1524-1528 ◽  
Author(s):  
Shih-Yi Lin ◽  
Ya-Yu Wang ◽  
Pi-Haw Liu ◽  
Wen-An Lai ◽  
Wayne Huey-Herng Sheu
Keyword(s):  
Metabolic Syndrome ◽  
Chinese Population ◽  
Free Thyroxine ◽  
Lower Serum ◽  
Serum Free ◽  
Serum Free Thyroxine

Factors Affecting the Serum Free Thyroxine Levels in Hospitalized Chronic Geriatric Patients

1993 ◽  
Vol 41 (7) ◽  
pp. 742-746 ◽  
Author(s):  
Istvan Szabolcs ◽  
Christoph Ploenes ◽  
Mathias Beyer ◽  
Wolfdieter Bernard ◽  
Jorg Herrmann
Keyword(s):  
Geriatric Patients ◽  
Free Thyroxine ◽  
Factors Affecting ◽  
Serum Free ◽  
Serum Free Thyroxine

scholarly journals Serum Free Thyroxine and Triiodothyronine Concentrations in Subacute Thyroiditis

1980 ◽  
Vol 56 (11) ◽  
pp. 1527-1534
Author(s):  
Katsumi YOSHIDA ◽  
Toshiro SAKURADA ◽  
Nobuko KAISE ◽  
Kazuo KAISE ◽  
Hirofumi KITAOKA ◽  
...  
Keyword(s):  
Free Thyroxine ◽  
Subacute Thyroiditis ◽  
Serum Free ◽  
Serum Free Thyroxine

scholarly journals Serum free thyroxine levels are associated with the efficacy of weight reduction therapy in obese female patients

2016 ◽  
Vol 63 (3) ◽  
pp. 221-229 ◽  
Author(s):  
Koshi Hashimoto ◽  
Tetsuya Tagami ◽  
Hajime Yamakage ◽  
Kazuya Muranaka ◽  
Masashi Tanaka ◽  
...  
Keyword(s):  
Weight Reduction ◽  
Free Thyroxine ◽  
Serum Free ◽  
Female Patients ◽  
Obese Female ◽  
Serum Free Thyroxine

scholarly journals Misleading results from immunoassays of serum free thyroxine in the presence of rheumatoid factor

1997 ◽  
Vol 43 (6) ◽  
pp. 957-962 ◽  
Author(s):  
Anthony G W Norden ◽  
Rodwin A Jackson ◽  
Lorraine E Norden ◽  
A Jane Griffin ◽  
Margaret A Barnes ◽  
...  
Keyword(s):  
Thyroid Hormone ◽  
Rheumatoid Factor ◽  
Equilibrium Dialysis ◽  
Thyroid Stimulating Hormone ◽  
Normal Serum ◽  
Free Thyroxine ◽  
Free Triiodothyronine ◽  
Serum Free ◽  
Serum Free Thyroxine ◽  
Stimulating Hormone

Abstract A novel interference with measurements of serum free thyroxine (FT4) caused by rheumatoid factor (RhF) is described. We found misleading, sometimes gross, increases of FT4 results in 5 clinically euthyroid elderly female patients with high RhF concentrations. All 5 patients had high FT4 on Abbott AxSYM® or IMx® analyzers. “NETRIA” immunoassays gave misleading results in 4 of the 5 patients; Amerlex-MAB® in 2 of 4 patients; AutoDELFIA®in 2 of the 5; and Corning ACS-180® and Bayer Diagnostics Immuno 1® in 1 of the 5. BM-ES700® system results for FT4 in these women remained within the reference range. Results for serum T4, thyroid-stimulating hormone, free triiodothyronine, thyroid-hormone-binding globulin, and FT4 measured by equilibrium dialysis were normal in all 5 patients. Drugs, albumin-binding variants, and anti-thyroid-hormone antibodies were excluded as interferences. Addition to normal serum of the RhF isolated from each of the 5 patients increased the apparent FT4 (Abbott AxSYM). Screening of 83 unselected patients demonstrated a highly significant positive correlation between FT4 (Abbott AxSYM) and RhF concentrations. Discrepant, apparently increased FT4 with a normal result for thyroid-stimulating hormone should lead to measurement of the patient’s RhF concentration.

Sign in / Sign up

Export Citation Format

Share Document