scholarly journals Clinicopathologic Features of Fatal Non-Anaplastic Follicular Cell–Derived Thyroid Carcinomas

Thyroid ◽  
2016 ◽  
Vol 26 (11) ◽  
pp. 1588-1597 ◽  
Author(s):  
Bin Xu ◽  
Tihana Ibrahimpasic ◽  
Laura Wang ◽  
Mona M. Sabra ◽  
Jocelyn C. Migliacci ◽  
...  
Keyword(s):  
Follicular Cell ◽  
Clinicopathologic Features ◽  
Thyroid Carcinomas

Prognostic significance of TERT promoter mutations in follicular cell-derived thyroid carcinomas

2014 ◽  
Author(s):  
Miguel Melo ◽  
Rocha Adriana Gaspar da ◽  
Joao Vinagre ◽  
Rui Batista ◽  
Joana Peixoto ◽  
...  
Keyword(s):  
Prognostic Significance ◽  
Follicular Cell ◽  
Thyroid Carcinomas ◽  
Tert Promoter ◽  
Tert Promoter Mutations ◽  
Promoter Mutations

scholarly journals Familial follicular cell thyroid carcinomas in a large number of Dutch German longhaired pointers

2021 ◽  
Author(s):  
Yun Yu ◽  
Adriana Krupa ◽  
Rebekah I. Keesler ◽  
Guy C. M. Grinwis ◽  
Mariska Ruijsscher ◽  
...  
Keyword(s):  
Follicular Cell ◽  
Thyroid Carcinomas

Problems and Controversies in the Histopathology of Thyroid Carcinomas of Follicular Cell Origin

2009 ◽  
Vol 133 (5) ◽  
pp. 683-691
Author(s):  
Ronald Ghossein
Keyword(s):  
Thyroid Carcinoma ◽  
English Language ◽  
Follicular Carcinoma ◽  
Molecular Data ◽  
Follicular Cell ◽  
Clinical Value ◽  
Thyroid Carcinomas ◽  
Poorly Differentiated ◽  
Disease Entities

Abstract Context.—Despite past and recent efforts, many problems and controversies remain in the classification of thyroid carcinomas of follicular cell origin. These controversies have an impact on the prognosis and therapy of patients with thyroid carcinoma as well as on the development of robust cutting-edge research aimed at better outcome and quality of life. Objective.—To focus on 3 contentious areas with significant clinical value: the follicular variant of papillary thyroid carcinoma, the extent of invasion in follicular carcinoma, and the poorly differentiated thyroid carcinomas. Data Sources.—The published English language literature was reviewed. Conclusions.—Recent data show that prognosis and therapy for many disease entities can be better delineated if a meticulous microscopic examination is performed. An accurate assessment of the extent of invasion (especially vascular) is crucial. Proliferative grading (ie, mitosis and necrosis) is of high prognostic value and should be looked for in every specimen. In addition, molecular data gathered to date can help reassess these tumors at the histologic level. Classification proposals based on personal experience rather than adequate and careful clinical follow-up should be discouraged.

scholarly journals Signaling pathways in follicular cell-derived thyroid carcinomas

2012 ◽  
Vol 42 (1) ◽  
pp. 19-28 ◽  
Author(s):  
MÍRIAN ROMITTI ◽  
LUCIELI CEOLIN ◽  
DÉBORA RODRIGUES SIQUEIRA ◽  
CARLA VAZ FERREIRA ◽  
SIMONE MAGAGNIN WAJNER ◽  
...  
Keyword(s):  
Signaling Pathways ◽  
Follicular Cell ◽  
Thyroid Carcinomas

scholarly journals Aggressive variants of follicular cell-derived thyroid carcinomas: A cytopathologist's perspective

2014 ◽  
Vol 122 (7) ◽  
pp. 484-503 ◽  
Author(s):  
Ricardo R. Lastra ◽  
Virginia A. LiVolsi ◽  
Zubair W. Baloch
Keyword(s):  
Follicular Cell ◽  
Thyroid Carcinomas

scholarly journals Clinicopathologic features of kinase fusion-related thyroid carcinomas: an integrative analysis with molecular characterization

2020 ◽  
Vol 33 (12) ◽  
pp. 2458-2472 ◽  
Author(s):  
Ying-Hsia Chu ◽  
Lori J. Wirth ◽  
Alexander A. Farahani ◽  
Vânia Nosé ◽  
William C. Faquin ◽  
...  
Keyword(s):  
Molecular Characterization ◽  
Integrative Analysis ◽  
Clinicopathologic Features ◽  
Thyroid Carcinomas

scholarly journals Clinicopathologic features andBRAFV600E mutation analysis in cutaneous metastases from well-differentiated thyroid carcinomas

Cancer ◽  
2007 ◽  
Vol 109 (10) ◽  
pp. 1965-1971 ◽  
Author(s):  
Lori A. Erickson ◽  
Long Jin ◽  
Nobuki Nakamura ◽  
Alina G. Bridges ◽  
Svetomir N. Markovic ◽  
...  
Keyword(s):  
Mutation Analysis ◽  
Clinicopathologic Features ◽  
Cutaneous Metastases ◽  
Thyroid Carcinomas ◽  
Well Differentiated

Different genotype distribution of theGNB3 C825T polymorphism of the G protein β3 subunit in adenomas and differentiated thyroid carcinomas of follicular cell origin

2005 ◽  
Vol 207 (4) ◽  
pp. 430-435 ◽  
Author(s):  
Sien-Yi Sheu ◽  
Rainer Görges ◽  
Christian Ensinger ◽  
Dietmar Öfner ◽  
Nadir R Farid ◽  
...  
Keyword(s):  
G Protein ◽  
Follicular Cell ◽  
Genotype Distribution ◽  
Thyroid Carcinomas ◽  
C825t Polymorphism

Parathyroid Gland Involvement by Papillary Carcinoma of the Thyroid Gland

2002 ◽  
Vol 126 (12) ◽  
pp. 1511-1514
Author(s):  
Weihua Tang ◽  
Kennichi Kakudo ◽  
Yasushi Nakamura ◽  
Misa Nakamura ◽  
Ichiro Mori ◽  
...  
Keyword(s):  
Thyroid Gland ◽  
Thyroid Carcinoma ◽  
Parathyroid Gland ◽  
Early Stage ◽  
Nodal Metastasis ◽  
Clinicopathologic Features ◽  
Papillary Thyroid ◽  
Primary Tumors ◽  
Thyroid Carcinomas ◽  
Direct Invasion

Abstract Objective.—To describe the phenomenon of parathyroid gland involvement by thyroid carcinoma and to explore its clinicopathologic significance. Design.—We reviewed the clinicopathologic features and described the histopathologic characteristics of 20 cases of parathyroid involvement found in a series of 911 papillary thyroid carcinomas. Results.—Parathyroid involvement occurred in 3 patterns: (1) direct invasion from the main tumor with an infiltrative growth, (2) invasion of the parathyroid gland with an expansive growth and formation of a pseudocapsule between the carcinoma and the parathyroid gland, and (3) metastatic deposition within the parathyroid gland itself. Among the 20 cases, 6 (30%) had primary tumors measuring 1 cm or less, and 14 (70%) had primary tumors measuring more than 1 cm. The cases with smaller primary tumors had a comparatively lower rate of nodal metastasis (50% vs 100%, P = .02). Furthermore, none of the cases with smaller primary tumors had invasion of extrathyroid structures other than parathyroid gland, but such invasion was common among the cases with larger primary tumors (0% vs 71%, P = .01). Conclusion.—To the best of our knowledge, this is the first report showing that parathyroid involvement occurs in papillary thyroid carcinomas even in the early stage of the disease.

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