scholarly journals Clinicopathologic features andBRAFV600E mutation analysis in cutaneous metastases from well-differentiated thyroid carcinomas

Cancer ◽  
2007 ◽  
Vol 109 (10) ◽  
pp. 1965-1971 ◽  
Author(s):  
Lori A. Erickson ◽  
Long Jin ◽  
Nobuki Nakamura ◽  
Alina G. Bridges ◽  
Svetomir N. Markovic ◽  
...  
Keyword(s):  
Mutation Analysis ◽  
Clinicopathologic Features ◽  
Cutaneous Metastases ◽  
Thyroid Carcinomas ◽  
Well Differentiated

scholarly journals Synchronous intrathyroidal parathyroid carcinoma and thyroid carcinoma: case report and review of the literature

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Nadia De Falco ◽  
Giuseppe Santangelo ◽  
Fabrizio Chirico ◽  
Angelo Cangiano ◽  
Maria Giulia Sommella ◽  
...  
Keyword(s):  
Literature Review ◽  
Thyroid Carcinoma ◽  
Papillary Carcinoma ◽  
Parathyroid Carcinoma ◽  
Malignant Tumors ◽  
Gamma Probe ◽  
Differentiated Thyroid Carcinoma ◽  
Thyroid Carcinomas ◽  
First Case ◽  
Well Differentiated

Abstract Background Parathyroid carcinoma is a rare endocrine malignancy, rarer when synchronous with a non medullary well differentiated thyroid carcinoma. Parathyroid carcinoma accounts of 0.005% of all malignant tumors and it is responsible for less than 1% of primary hyperparathyroidism. The intrathyroidal localization of a parathyroid gland is not frequent with a reported prevalence of 0.2%. Carcinoma of parathyroids with intrathyroidal localization represents an even rarer finding, reported in only 16 cases described in literature. The rare constellation of synchronous parathyroid and thyroid carcinomas has prompted us to report our experience and perform literature review. Case presentation We herein report a case of a 63-years-old man with multinodular goiter and biochemical diagnosis of hyperparathyroidism. Total thyroidectomy with radio-guide technique using gamma probe after intraoperative sesta-MIBI administration and intraoperative PTH level was performed. The high radiation levels in the posterior thyroid lobe discovered an intrathyroidal parathyroid. Microscopic examination revealed a parathyroid main cell carcinoma at the posterior thyroidal left basal lobe, a classic papillary carcinoma at the same lobe and follicular variant of papillary carcinoma at the thyroidal right lobe. To the best of our knowledge, this is the first case documenting a synchronous multicentric non medullary thyroid carcinomas and intrathyroidal parathyroid carcinoma. Conclusions Our experience was reported and literature review underlining challenging difficulties in diagnostic workup and surgical management was carried out.

Multifocality in well-differentiated thyroid carcinomas calls for total thyroidectomy

2011 ◽  
Vol 201 (6) ◽  
pp. 770-775 ◽  
Author(s):  
Haggi Mazeh ◽  
Yacov Samet ◽  
David Hochstein ◽  
Ido Mizrahi ◽  
Ilana Ariel ◽  
...  
Keyword(s):  
Total Thyroidectomy ◽  
Thyroid Carcinomas ◽  
Well Differentiated

Testicular Extramedullary Myeloid Cell Tumor: Report of a Case With Unique Clinicopathologic Features and a Brief Review of the Literature

2004 ◽  
Vol 128 (3) ◽  
pp. 332-334 ◽  
Author(s):  
Ajay Rawal ◽  
Thomas C. Keeler ◽  
Michelangelo A. Milano
Keyword(s):  
Clinical Features ◽  
Myeloid Cell ◽  
Cell Tumor ◽  
Seminiferous Tubules ◽  
Clinicopathologic Features ◽  
Review Of The Literature ◽  
Pathologic Examination ◽  
Tumor Mass ◽  
Well Differentiated ◽  
Tumor Infiltrate

Abstract We report a case of testicular extramedullary myeloid cell tumor in a 37-year-old man who presented with an acute testicular hemorrhage. A pathologic examination revealed no gross tumor mass. A well-differentiated extramedullary myeloid cell tumor infiltrate was seen histologically, localized largely to the seminiferous tubules. The patient had no evidence of any past or concurrent myeloid disorders. The lack of the usual clinical features of a testicular mass and the presence of an intratubular pattern of infiltration can further compound the challenges in diagnosing this entity.

BRAF V600E Mutation Analysis in Papillary Thyroid Carcinomas by Peptide Nucleic Acid Clamp Real-time PCR

2012 ◽  
Vol 20 (3) ◽  
pp. 759-766 ◽  
Author(s):  
Dongjun Jeong ◽  
Yujun Jeong ◽  
Ji Hye Park ◽  
Sun Wook Han ◽  
Sung Yong Kim ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Real Time ◽  
Mutation Analysis ◽  
Real Time Pcr ◽  
Peptide Nucleic Acid ◽  
Braf V600e Mutation ◽  
Braf V600e ◽  
Papillary Thyroid ◽  
Thyroid Carcinomas

scholarly journals Mutation Analysis of RAP1 Gene in Papillary Thyroid Carcinomas

2009 ◽  
Vol 56 (1) ◽  
pp. 161-164 ◽  
Author(s):  
Michiko MATSUSE ◽  
Norisato MITSUTAKE ◽  
Tatiana ROGOUNOVITCH ◽  
Vladimir SAENKO ◽  
Yuka NAKAZAWA ◽  
...  
Keyword(s):  
Mutation Analysis ◽  
Papillary Thyroid ◽  
Thyroid Carcinomas

scholarly journals Molecular characterization of well-differentiated human thyroid carcinomas by cDNA arrays

2006 ◽  
Author(s):  
Jianming Zhao ◽  
Christa Leonard ◽  
Erich Brunner ◽  
Ernst Gemsenjäger ◽  
Philipp Heitz ◽  
...  
Keyword(s):  
Molecular Characterization ◽  
Human Thyroid ◽  
Thyroid Carcinomas ◽  
Cdna Arrays ◽  
Well Differentiated
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