scholarly journals Human Perivascular Stem Cells Show Enhanced Osteogenesis and Vasculogenesis with Nel-Like Molecule I Protein

2013 ◽  
Vol 19 (11-12) ◽  
pp. 1386-1397 ◽  
Author(s):  
Asal Askarinam ◽  
Aaron W. James ◽  
Janette N. Zara ◽  
Raghav Goyal ◽  
Mirko Corselli ◽  
...  
Keyword(s):  
Stem Cells ◽  
Perivascular Stem Cells

scholarly journals Different Angiogenic Potentials of Mesenchymal Stem Cells Derived from Umbilical Artery, Umbilical Vein, and Wharton’s Jelly

2017 ◽  
Vol 2017 ◽  
pp. 1-15 ◽  
Author(s):  
Lu Xu ◽  
Jianjun Zhou ◽  
Jingyu Liu ◽  
Yong Liu ◽  
Lei Wang ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Umbilical Vein ◽  
Wharton’S Jelly ◽  
Tube Length ◽  
Branch Points ◽  
Differentiation Potential ◽  
Wharton's Jelly ◽  
Allogeneic Cell Therapy ◽  
Perivascular Stem Cells

Human mesenchymal stem cells derived from the umbilical cord (UC) are a favorable source for allogeneic cell therapy. Here, we successfully isolated the stem cells derived from three different compartments of the human UC, including perivascular stem cells derived from umbilical arteries (UCA-PSCs), perivascular stem cells derived from umbilical vein (UCV-PSCs), and mesenchymal stem cells derived from Wharton’s jelly (WJ-MSCs). These cells had the similar phenotype and differentiation potential toward adipocytes, osteoblasts, and neuron-like cells. However, UCA-PSCs and UCV-PSCs had more CD146+ cells than WJ-MSCs (P<0.05). Tube formation assay in vitro showed the largest number of tube-like structures and branch points in UCA-PSCs among the three stem cells. Additionally, the total tube length in UCA-PSCs and UCV-PSCs was significantly longer than in WJ-MSCs (P<0.01). Microarray, qRT-PCR, and Western blot analysis showed that UCA-PSCs had the highest expression of the Notch ligand Jagged1 (JAG1), which is crucial for blood vessel maturation. Knockdown of Jagged1 significantly impaired the angiogenesis in UCA-PSCs. In summary, UCA-PSCs are promising cell populations for clinical use in ischemic diseases.

scholarly journals Perivascular Stem Cells at the Tip of Mouse Incisors Regulate Tissue Regeneration

2015 ◽  
Vol 31 (3) ◽  
pp. 514-523 ◽  
Author(s):  
Yvonne WY Pang ◽  
Jifan Feng ◽  
Felipe Daltoe ◽  
Robert Fatscher ◽  
Eileen Gentleman ◽  
...  
Keyword(s):  
Stem Cells ◽  
Tissue Regeneration ◽  
Perivascular Stem Cells

scholarly journals Human perivascular stem cells prevent bone graft resorption in osteoporotic contexts by inhibiting osteoclast formation

2020 ◽  
Vol 9 (12) ◽  
pp. 1617-1630 ◽  
Author(s):  
Stefano Negri ◽  
Yiyun Wang ◽  
Takashi Sono ◽  
Seungyong Lee ◽  
Ginny Ching‐Yun Hsu ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Graft ◽  
Osteoclast Formation ◽  
Perivascular Stem Cells ◽  
Graft Resorption

Perivascular Stem Cells Diminish Muscle Atrophy Following Massive Rotator Cuff Tears in a Small Animal Model

2017 ◽  
Vol 99 (4) ◽  
pp. 331-341 ◽  
Author(s):  
Claire D. Eliasberg ◽  
Ayelet Dar ◽  
Andrew R. Jensen ◽  
Iain R. Murray ◽  
Winters R. Hardy ◽  
...  
Keyword(s):  
Stem Cells ◽  
Animal Model ◽  
Rotator Cuff ◽  
Muscle Atrophy ◽  
Small Animal ◽  
Rotator Cuff Tears ◽  
Small Animal Model ◽  
Massive Rotator Cuff Tears ◽  
Perivascular Stem Cells

scholarly journals WISP-1 drives bone formation at the expense of fat formation in human perivascular stem cells

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Carolyn A. Meyers ◽  
Jiajia Xu ◽  
Greg Asatrian ◽  
Catherine Ding ◽  
Jia Shen ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Formation ◽  
Perivascular Stem Cells

Cross-talk of perivascular stem cells and homodynamics

2008 ◽  
Vol 1 (6) ◽  
pp. 324-325
Author(s):  
Ramin Mostofi Zadeh Farahani ◽  
Atabak Shahidi
Keyword(s):  
Stem Cells ◽  
Cross Talk ◽  
Perivascular Stem Cells
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