Low-Level Laser Therapy to the Bone Marrow Reduces Scarring and Improves Heart Function Post-Acute Myocardial Infarction in the Pig

2016 ◽  
Vol 34 (11) ◽  
pp. 516-524 ◽  
Author(s):  
Alex Blatt ◽  
Gabby A. Elbaz-Greener ◽  
Hana Tuby ◽  
Lidya Maltz ◽  
Yariv Siman-Tov ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Bone Marrow ◽  
Laser Therapy ◽  
Heart Function ◽  
Low Level Laser Therapy ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser

Bone marrow aspirate combined with low-level laser therapy: A new therapeutic approach to enhance bone healing

2013 ◽  
Vol 121 ◽  
pp. 6-14 ◽  
Author(s):  
Maria J.H. Nagata ◽  
Carolina S. Santinoni ◽  
Natália M. Pola ◽  
Natália de Campos ◽  
Michel R. Messora ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Laser Therapy ◽  
Bone Healing ◽  
Therapeutic Approach ◽  
Bone Marrow Aspirate ◽  
Low Level Laser Therapy ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser

Effect of in vivo low-level laser therapy on bone marrow-derived mesenchymal stem cells in ovariectomy-induced osteoporosis of rats

2017 ◽  
Vol 175 ◽  
pp. 29-36 ◽  
Author(s):  
Ataroalsadat Mostafavinia ◽  
Leila Dehdehi ◽  
Seyed Kamran Ghoreishi ◽  
Behnam Hajihossainlou ◽  
Mohammad Bayat
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Laser Therapy ◽  
Low Level Laser Therapy ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser

Abstract 423: Low Level Laser Therapy Stimulates Hypoxia-Inducible Factor Expression and Increases MicroRNA 210 Content after Rat Myocardial Infarction

Hypertension ◽  
2014 ◽  
Vol 64 (suppl_1) ◽  
Author(s):  
Jose A Silva ◽  
Regiane S Feliciano ◽  
Andrey J Serra ◽  
Martha T Manchini ◽  
Eduardo T Santana ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Laser Irradiation ◽  
Laser Therapy ◽  
Systolic Dysfunction ◽  
Hypoxia Inducible Factor ◽  
Micro Rna ◽  
Low Level Laser Therapy ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser

Low-level laser therapy (LLLT) has been used as an anti-inflammatory alternative treatment in several disease conditions, even when inflammation is a secondary consequence, such as in myocardial infarction (MI). LLLT treatment effectively reduces MI size and attenuates the systolic dysfunction after MI. However, the mechanism by which LLLT is able to protect the remaining myocardium remains unclear. Here, we tested the hypothesis that LLLT might reduce the hypoxia effects generated by MI. To achieve this purpose, we evaluated, after laser irradiation, the modulation of hypoxia-inducible factor (HIF) and microRNA 210 expressions, which are consistently stimulated under hypoxic conditions. We observed that HIF content presented an up-regulation after MI, however, a significant augmented HIF expression was observed after LLLT. Accordingly, micro-RNA 210 expression in the MI remote area increased even further after laser irradiation. Our data suggest that LLLT stimulates HIF expression pathway, increasing hypoxia-induced microRNA 210 content after MI, therefore, highlighting a possible cardioprotective role of LLLT.

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