Low-Level Laser Irradiation Alters Cardiac Cytokine Expression Following Acute Myocardial Infarction: A Potential Mechanism for Laser Therapy

2011 ◽  
Vol 29 (6) ◽  
pp. 391-398 ◽  
Author(s):  
Zhikai Yang ◽  
Yihe Wu ◽  
Hao Zhang ◽  
Peifeng Jin ◽  
Wei Wang ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Laser Irradiation ◽  
Laser Therapy ◽  
Cytokine Expression ◽  
Potential Mechanism ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser ◽  
Low Level Laser Irradiation

Abstract 423: Low Level Laser Therapy Stimulates Hypoxia-Inducible Factor Expression and Increases MicroRNA 210 Content after Rat Myocardial Infarction

Hypertension ◽  
2014 ◽  
Vol 64 (suppl_1) ◽  
Author(s):  
Jose A Silva ◽  
Regiane S Feliciano ◽  
Andrey J Serra ◽  
Martha T Manchini ◽  
Eduardo T Santana ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Laser Irradiation ◽  
Laser Therapy ◽  
Systolic Dysfunction ◽  
Hypoxia Inducible Factor ◽  
Micro Rna ◽  
Low Level Laser Therapy ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser

Low-level laser therapy (LLLT) has been used as an anti-inflammatory alternative treatment in several disease conditions, even when inflammation is a secondary consequence, such as in myocardial infarction (MI). LLLT treatment effectively reduces MI size and attenuates the systolic dysfunction after MI. However, the mechanism by which LLLT is able to protect the remaining myocardium remains unclear. Here, we tested the hypothesis that LLLT might reduce the hypoxia effects generated by MI. To achieve this purpose, we evaluated, after laser irradiation, the modulation of hypoxia-inducible factor (HIF) and microRNA 210 expressions, which are consistently stimulated under hypoxic conditions. We observed that HIF content presented an up-regulation after MI, however, a significant augmented HIF expression was observed after LLLT. Accordingly, micro-RNA 210 expression in the MI remote area increased even further after laser irradiation. Our data suggest that LLLT stimulates HIF expression pathway, increasing hypoxia-induced microRNA 210 content after MI, therefore, highlighting a possible cardioprotective role of LLLT.

scholarly journals Exploring the ability of low-level laser irradiation to reduce myonecrosis and increase Myogenin transcription after Bothrops jararacussu envenomation

2021 ◽  
Vol 20 (4) ◽  
pp. 571-583
Author(s):  
Willians Fernando Vieira ◽  
Bruno Kenzo-Kagawa ◽  
Lúcia Elvira Alvares ◽  
José Carlos Cogo ◽  
Vitor Baranauskas ◽  
...  
Keyword(s):  
Laser Irradiation ◽  
Bothrops Jararacussu ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser ◽  
Low Level Laser Irradiation
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