Neuroprotective Effects of the Methanol Extract of Kimchi, a Korean Fermented Vegetable Food, Mediated Via Suppression of Endoplasmic Reticulum Stress and Caspase Cascade Pathways in High-Cholesterol Diet-Fed Mice

2018 ◽  
Vol 21 (5) ◽  
pp. 489-495
Author(s):  
Serim Kim ◽  
Minji Woo ◽  
Mijeong Kim ◽  
Jeong Sook Noh ◽  
Yeong Ok Song
Keyword(s):  
Endoplasmic Reticulum ◽  
Endoplasmic Reticulum Stress ◽  
Methanol Extract ◽  
High Cholesterol Diet ◽  
Cholesterol Diet ◽  
High Cholesterol ◽  
Neuroprotective Effects ◽  
Vegetable Food ◽  
Caspase Cascade

Neuroprotective effects of phytosterol esters against high cholesterol-induced cognitive deficits in aged rat

2017 ◽  
Vol 8 (3) ◽  
pp. 1323-1332 ◽  
Author(s):  
Xu Rui ◽  
Li Wenfang ◽  
Cheng Jing ◽  
Chen Meng ◽  
Ding Chengcheng ◽  
...  
Keyword(s):  
Animal Models ◽  
Cognitive Performance ◽  
Cognitive Deficits ◽  
Experimental Studies ◽  
High Cholesterol Diet ◽  
Cholesterol Diet ◽  
High Cholesterol ◽  
Neuroprotective Effects ◽  
Aged Rat ◽  
Phytosterol Esters

Accumulating epidemiological and experimental studies have confirmed that a high-cholesterol diet is detrimental to cognitive performance in animal models.

scholarly journals Sericin ameliorated dysmorphic mitochondria in high-cholesterol diet/streptozotocin rat by antioxidative property

2016 ◽  
Vol 242 (4) ◽  
pp. 411-421 ◽  
Author(s):  
Sumate Ampawong ◽  
Duangnate Isarangkul ◽  
Pornanong Aramwit
Keyword(s):  
Endoplasmic Reticulum ◽  
Exocrine Pancreas ◽  
Protective Role ◽  
Blood Cholesterol ◽  
High Cholesterol Diet ◽  
Zymogen Granule ◽  
Cholesterol Diet ◽  
High Cholesterol ◽  
Electron Microscopic ◽  
Antioxidative Property

Sericin has been implicated in lower cholesterolemic effect due to its properties with several mechanisms. Mitochondria are one of the most important targets to be affected in high blood cholesterol and glucose conditions. The protective role of sericin on mitochondria remains doubtful. To examine this role, electron microscopic, histopathologic, immunohistochemical, and biochemical studies were performed in a high-cholesterol diet/streptozotocin rat model. The results demonstrated that sericin reduced blood cholesterol without hypoglycemic effect. Sericin alleviated dysmorphic mitochondria in heart and liver but not in kidney and also decreased peculiar endoplasmic reticulum in the exocrine pancreas. In addition, sericin decreased hepatic steatosis and preserved zymogen granule referable to the decline of reactive oxygen species production in hepatic mitochondrial extraction and down-regulation of malondialdehyde expression in the liver and exocrine pancreas however irrelevant to lipase activity. This study suggests that sericin has antioxidative property to reduce blood cholesterol by means of diminishing fat deposit in hepatocyte and improves mitochondria and endoplasmic reticulum integrities. [Box: see text]

Hypolipidemic and antioxidant effect of Ajuga iva in rats fed a high-cholesterol diet

Planta Medica ◽  
2006 ◽  
Vol 72 (11) ◽  
Author(s):  
MA Lacaille-Dubois ◽  
A Chenni ◽  
DA Yahia ◽  
FO Boukortt ◽  
J Prost ◽  
...  
Keyword(s):  
Antioxidant Effect ◽  
High Cholesterol Diet ◽  
Cholesterol Diet ◽  
High Cholesterol

Serum lipoproteins of diabetic rats fed a high cholesterol diet

Diabetes ◽  
1980 ◽  
Vol 29 (10) ◽  
pp. 774-777 ◽  
Author(s):  
C. M. Arbeeny ◽  
D. Edelstein ◽  
S. R. Freedman ◽  
H. A. Eder
Keyword(s):  
Diabetic Rats ◽  
High Cholesterol Diet ◽  
Cholesterol Diet ◽  
Serum Lipoproteins ◽  
High Cholesterol

Effect of Polygonum multiflorum Thunberg Extract on Lipid Metabolism in Rats Fed High-Cholesterol Diet

2012 ◽  
Vol 41 (7) ◽  
pp. 957-962 ◽  
Author(s):  
Jun-Hweok Choi ◽  
Hye-Sung Lee ◽  
Young-Eon Kim ◽  
Byoung-Mok Kim ◽  
In-Ho Kim ◽  
...  
Keyword(s):  
Lipid Metabolism ◽  
High Cholesterol Diet ◽  
Cholesterol Diet ◽  
High Cholesterol ◽  
Polygonum Multiflorum
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