scholarly journals Dengue Virus Infection of Primary Endothelial Cells Induces Innate Immune Responses, Changes in Endothelial Cells Function and Is Restricted by Interferon-Stimulated Responses

2015 ◽  
Vol 35 (8) ◽  
pp. 654-665 ◽  
Author(s):  
Julie K. Calvert ◽  
Karla J. Helbig ◽  
David Dimasi ◽  
Michaelia Cockshell ◽  
Michael R. Beard ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Virus Infection ◽  
Immune Responses ◽  
Dengue Virus ◽  
Innate Immune ◽  
Innate Immune Responses ◽  
Dengue Virus Infection

scholarly journals Aedes aegypti Saliva Enhances Dengue Virus Infection of Human Keratinocytes by Suppressing Innate Immune Responses

2012 ◽  
Vol 132 (8) ◽  
pp. 2103-2105 ◽  
Author(s):  
Pornapat Surasombatpattana ◽  
Sirilaksana Patramool ◽  
Natthanej Luplertlop ◽  
Hans Yssel ◽  
Dorothée Missé
Keyword(s):  
Virus Infection ◽  
Aedes Aegypti ◽  
Immune Responses ◽  
Dengue Virus ◽  
Human Keratinocytes ◽  
Innate Immune ◽  
Innate Immune Responses ◽  
Dengue Virus Infection

scholarly journals The Ubiquitin−Proteasome Pathway Is Important for Dengue Virus Infection in Primary Human Endothelial Cells

2010 ◽  
Vol 9 (10) ◽  
pp. 4960-4971 ◽  
Author(s):  
Rattiyaporn Kanlaya ◽  
Sa-nga Pattanakitsakul ◽  
Supachok Sinchaikul ◽  
Shui-Tein Chen ◽  
Visith Thongboonkerd
Keyword(s):  
Endothelial Cells ◽  
Virus Infection ◽  
Dengue Virus ◽  
Human Endothelial Cells ◽  
Dengue Virus Infection ◽  
Ubiquitin Proteasome Pathway ◽  
Ubiquitin Proteasome ◽  
Proteasome Pathway

scholarly journals CLINICAL MANIFESTATION APPROACH OF DENGUE VIRAL INFECTION

2016 ◽  
Vol 6 (2) ◽  
pp. 39
Author(s):  
Nasronudin Nasronudin
Keyword(s):  
Immune Response ◽  
Endothelial Cells ◽  
Immune Responses ◽  
Dengue Virus ◽  
Dengue Shock Syndrome ◽  
Capillary Leakage ◽  
Dengue Virus Infection ◽  
Effective Strategies ◽  
Severe Hemorrhage ◽  
Coagulation And Fibrinolysis

Currently by an estimated 50-100 million dengue fever cases per year in worldwide, 500.000 were in the form of a disease is heavyDengue Hemorraghic Fever (DHF) and Dengue Shock Syndrome (DSS). Survey serology in Indonesia show that DEN-1 and DEN-2 arethe dominant serotipe virus until the end of the 1980s but the recent shift has occurred epizoötic where viruses DEN-3 dominant. (DosSantos, 2004; Malavige, 2004; Stephenson, 2005). Dengue virus infection induces transient immune aberrant activation of CD4/CD8ratio inversion and cytokine overproduction, and infection of endothelial cells and hepatocytes causes apoptosis and dysfunction ofthese cells. The aberrant immune responses not only impaire the immune response to clear the virus, but also result in overproductionof cytokines that affect monocytes, endothelial cells, and hepatocytes. Dengue-virus-induced vasculopathy and coagulopathy must beinvolved in the pathogenesis of hemorrhage, and the unbalace between coagulation and fibrinolysis activation, and prolonged durationof shock increase the likelihood of severe hemorrhage in DHF/DSS. Capillary leakage is triggered by the dengue virus itself or byantibodies to its antigen. To date, there are no effective strategies to prevent the progression of DHF/DSS. The control of dengue willbe possible only after an efficient vaccine has been developed

scholarly journals Senescence Affects Endothelial Cells Susceptibility to Dengue Virus Infection

2014 ◽  
Vol 11 (6) ◽  
pp. 538-544 ◽  
Author(s):  
Sazaly AbuBakar ◽  
Meng-Hooi Shu ◽  
Jefree Johari ◽  
Pooi-Fong Wong
Keyword(s):  
Endothelial Cells ◽  
Virus Infection ◽  
Dengue Virus ◽  
Dengue Virus Infection

scholarly journals Dengue Virus Infection Mediates HMGB1 Release from Monocytes Involving PCAF Acetylase Complex and Induces Vascular Leakage in Endothelial Cells

PLoS ONE ◽  
2012 ◽  
Vol 7 (7) ◽  
pp. e41932 ◽  
Author(s):  
Siew Pei Ong ◽  
Ling Min Lee ◽  
Yew Fai Ivan Leong ◽  
Mah Lee Ng ◽  
Justin Jang Hann Chu
Keyword(s):  
Endothelial Cells ◽  
Virus Infection ◽  
Dengue Virus ◽  
Vascular Leakage ◽  
Dengue Virus Infection
Sign in / Sign up

Export Citation Format

Share Document