scholarly journals Correction to: Recent Progress on Genetic Diagnosis and Therapy for β-Thalassemia in China and Around the World, by Zhang J, Yan J, and Zeng F.Hum Gene Ther 2018;29(2):197–203.DOI: 10.1089/hum.2017.228

2018 ◽  
Vol 29 (3) ◽  
pp. 400-400 ◽  
Keyword(s):  
Recent Progress ◽  
Genetic Diagnosis ◽  
Diagnosis And Therapy ◽  
The World

Recent Progress in Functional Peptides Designed for Tumor-targeted Imaging and Therapy

2021 ◽  
Author(s):  
Xingyu Wang ◽  
Yi-Hui Wang ◽  
Zhen Song ◽  
Xin-Yuan Hu ◽  
Jiping Wei ◽  
...  
Keyword(s):  
Recent Progress ◽  
Targeted Imaging ◽  
Medical Field ◽  
Diagnosis And Therapy ◽  
Low Toxicity ◽  
Functional Peptides ◽  
Living Organisms

The diagnosis and therapy of tumors are challenging problems in the medical field. Peptides are derived from living organisms with excellent biocompatibility, low-toxicity/non-toxicity, and negligible immunogenicity, and they have been...

Managing Director's Statement on Strengthening Surveillance - 2011 Triennial Surveillance Review

Policy Papers ◽  
2011 ◽  
Vol 2011 (87) ◽  
Author(s):  
Keyword(s):  
World Economy ◽  
Recent Progress ◽  
Executive Directors ◽  
Executive Board ◽  
The World ◽  
Near Term

After inputs from country authorities, outside experts, and staff; after extensive deliberations at the Executive Board; after further guidance from ministers and governors at the IMFC meetings—after all that, we need to move from diagnosis to action. The goal of making surveillance as interconnected as the world economy remains an inherently long-term endeavor. Nevertheless, building on recent progress, we can do better even in the near term. I want to take this opportunity to put forward some specific measures, based on Executive Directors’ many thoughtful comments and suggestions (Table 1)

scholarly journals Z pinches—A historical view

2001 ◽  
Vol 19 (4) ◽  
pp. 509-525 ◽  
Author(s):  
R.B. SPIELMAN ◽  
J.S. DE GROOT
Keyword(s):  
Recent Progress ◽  
18Th Century ◽  
Nuclear Fusion ◽  
Energy Gain ◽  
Fusion Program ◽  
Historical View ◽  
Negative Results ◽  
The World ◽  
Fusion Concept ◽  
Varied History

Z pinches have a long and varied history. Beginning in the 18th century, z pinches have been used to heat plasmas very efficiently. Early in the nuclear fusion program, it was realized that modest currents are required to confine plasma that could produce energy gain. The instability of the confined plasma was convincingly demonstrated in experiments in the 1950s that were performed around the world. These uniformly negative results led to z pinches being dropped as a fusion concept. Recent progress in fast z pinches has reinvigorated the field. We review the field and highlight the recent advances that point the way to a bright future for z pinches.

scholarly journals Recent progress on detecting understanding and controlling Pseudomonas syringae pv actinidiae a short review

2013 ◽  
Vol 66 ◽  
pp. 170-177 ◽  
Author(s):  
J.L. Vanneste
Keyword(s):  
Pseudomonas Syringae ◽  
Recent Progress ◽  
Short Review ◽  
Economic Importance ◽  
Whole Genome Sequence ◽  
Bacterial Canker ◽  
New Methods ◽  
The World ◽  
Epiphytic Survival ◽  
Made In

In the last few years the causal agent of bacterial canker of kiwifruit Pseudomonas syringae pv actinidiae (Psa) has become a global pathogen of economic importance Since the beginning of this global outbreak many laboratories in the world have been working on Psa Today it is known that Psa is not a homogeneous pathovar and tools that allow the distinction between biovars (subpathovar classification) have been developed The whole genome sequence of several strains of Psa has now been published Some of the assumptions on the life cycle (ports of entry epiphytic survival etc) made in the early days of the outbreak have now been confirmed Although few new methods have been found to control Psa there is now a better understanding of how to reduce the incidence of this disease This paper reviews the progress made in understanding the pathogen the disease and how to control it

scholarly journals Prevention of Thalassaemia by Genetic Counseling

1970 ◽  
Vol 2 (2) ◽  
pp. 26-28 ◽  
Author(s):  
Syed Khairul Amin
Keyword(s):  
Health Education ◽  
Geographical Variation ◽  
Genetic Diagnosis ◽  
Carrier State ◽  
World Health ◽  
Community Based ◽  
Education Community ◽  
The World ◽  
Hb E ◽  
Health Organization

Thalassaemia is the most common inherited disorder in the world with a wide geographical variation in incidence. According to World Health Organization (WHO) at last 30% of Bangladesh population are carrions of Beta thalassaemia and 4.0% are carriers of Hb-E in Bangladesh. It is presumed that approximately 6000 thalassaemic children are born each year in Bangladesh. A recent study showed that carrier state of Hb-E is 6.1% and as high as 40% in Tribal children in Bangladesh. Early genetic, diagnosis, proper counseling, Health Education Community based prevention are necessary for the improvement of this inherited disorder in Bangladesh. Key Words: Thalassaemia; Bangladesh; Early Diagnosis; Counselings; Community Based Prevention; Health Education DOI: http://dx.doi.org/10.3329/akmmcj.v2i2.8169 AKMMC J 2011; 2(2): 26-28

scholarly journals Precision Medicine in Rare Diseases

Diseases ◽  
2020 ◽  
Vol 8 (4) ◽  
pp. 42
Author(s):  
Irene Villalón-García ◽  
Mónica Álvarez-Córdoba ◽  
Juan Miguel Suárez-Rivero ◽  
Suleva Povea-Cabello ◽  
Marta Talaverón-Rey ◽  
...  
Keyword(s):  
Personalized Medicine ◽  
Rare Diseases ◽  
Scientific Community ◽  
Genetic Diagnosis ◽  
World Health ◽  
Diagnostic Odyssey ◽  
The World ◽  
Pharmacological Screening ◽  
Health Organization ◽  
Low Prevalence

Rare diseases are those that have a low prevalence in the population (less than 5 individuals per 10,000 inhabitants). However, infrequent pathologies affect a large number of people, since according to the World Health Organization (WHO), there are about 7000 rare diseases that affect 7% of the world’s population. Many patients with rare diseases have suffered the consequences of what is called the diagnostic odyssey, that is, extensive and prolonged serial tests and clinical visits, sometimes for many years, all with the hope of identifying the etiology of their disease. For patients with rare diseases, obtaining the genetic diagnosis can mean the end of the diagnostic odyssey, and the beginning of another, the therapeutic odyssey. This scenario is especially challenging for the scientific community, since more than 90% of rare diseases do not currently have an effective treatment. This therapeutic failure in rare diseases means that new approaches are necessary. Our research group proposes that the use of precision or personalized medicine techniques can be an alternative to find potential therapies in these diseases. To this end, we propose that patients’ own cells can be used to carry out personalized pharmacological screening for the identification of potential treatments.

Influence of the awareness of COVID-19 pandemic on assisted reproductive technology clinic in Africa, South of the Sahara

2020 ◽  
Vol 11 (5) ◽  
Author(s):  
Bamgboye M Afolabi ◽  
Abayomi B Ajayi ◽  
Tola Ajayi ◽  
Victor D Ajayi ◽  
Ifeoluwa Oyetunji ◽  
...  
Keyword(s):  
Assisted Reproductive Technology ◽  
Genetic Diagnosis ◽  
Health And Safety ◽  
Face Mask ◽  
Reproductive Technology ◽  
Fertility Treatment ◽  
Left Behind ◽  
The World ◽  
The Government ◽  
Clinic Manager

Introduction: COVID-19 pandemic has taken the world by storm and consequently, various reproductive medicine societies had since issued guidelines based on best judgement for the safety of IVF patients and attending health staffs Objective: The objective of this study was to assess the opinions of IVF staff in sub-Sahara Africa on the awareness of COVID-19 on Assisted Reproductive Technology. The study also evaluated some of the measures that can mitigate the effects of the virus in IVF clinics. Methodology: Different cadres of staff at Nordica Fertility Center (NFC) in Lagos, Nigeria were interviewed. Those interviewed included the Medical Director, Clinicians/Gynecologists, Clinic Manager, Nurses, Embryologists, Counsellor, Business Developing Unit, Client Liaison Officers and Accounts Officer. Their responses were collated, and the key points were documented. Each staff in face mask was visited by one interviewer who observed all government-recommended sanitary precautions including wearing a facemask and maintaining social distance between her and the interviewee. Result: The response of the MD on the fate of IVF clinic in Africa within the next 6 months to 1 year of the Covid-19 pandemic was that the overall economy is a major determinant of the ability of clients to pay for IVF services. Infertile women would still want to have children but “how would they pay for the services?” since ART is not subsidized by the government but mostly paid as out-of-pocket expense in this part of the world. The main points were that IVF clinics are not immune to the economy and vaccine may or may not favor IVF, reasons being; The virus is about 5 months old hence still much to be discovered There is no solid evidence that the virus affects reproduction No evidence of mother-to-child transmission and The virus can survive in cold environment therefore, it could survive cryopreservation. The embryologist was of the opinion that IVF clinics in Africa need to understand the virus more to decide whether: Attend to COVID-19 patients or not and if so, how best to care for them Better prepare modalities of cryopreservation such as Appropriate equipment Batching gametes together with HIV or Hepatitis patients In same or separate equipment and Getting special cryo-tanks for Covid-19 patients. Embryologist agreed that clinics will be able to perform other adjunct fertility treatment such as Pre-implantation Genetic Diagnosis (PGD), dependent on clinics’ ability to have separate equipment for Covid19-positive and negative patients. Conclusion: Africa is not left behind in experiencing the effects of COVID-19 and ART, for which concerns for the survival of privately owned clinics to ensure and safeguard the health and safety of patients, staff and the unborn babies are expressed. As of now, no-one is sure of patients that are symptomatic and those not symptomatic, as testing in the country, just like in most parts of the world, are still inadequate. When a vaccine is available, it may be mandatory for every IVF patient to get a shot. The main points of other cadres of staff are discussed.

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