IL-28B Genetic Variant Is Associated with the Risk of Schizophrenia in the Chinese Han Population

2012 ◽  
Vol 31 (6) ◽  
pp. 988-992 ◽  
Author(s):  
Chunxia Chen ◽  
Bin Tan ◽  
Yi Zhou ◽  
Juan Zhou ◽  
Yong He ◽  
...  
2020 ◽  
Vol 40 (9) ◽  
pp. 2194-2202
Author(s):  
Haizhen Chen ◽  
Yanfang Zhang ◽  
Tongsheng Guo ◽  
Funing Yang ◽  
Yuanli Mao ◽  
...  

2018 ◽  
Vol 82 (1) ◽  
pp. 224-231 ◽  
Author(s):  
Yicong Ye ◽  
Xinglin Yang ◽  
Bo Long ◽  
Haiyu Pang ◽  
Yicheng Zhu ◽  
...  

Aging ◽  
2020 ◽  
Vol 12 (9) ◽  
pp. 7694-7703
Author(s):  
Renjie Xu ◽  
Xin Jiang ◽  
Junlan Lu ◽  
Kexin Wang ◽  
Ye Sun ◽  
...  

BMC Cancer ◽  
2011 ◽  
Vol 11 (1) ◽  
Author(s):  
Keke Zhou ◽  
Dezhi Hu ◽  
Juan Lu ◽  
Weiwei Fan ◽  
Hongliang Liu ◽  
...  

2019 ◽  
Vol 3 (2) ◽  
pp. 78
Author(s):  
Lin An ◽  
Chuanxin Liu ◽  
Naixin Zhang ◽  
Zhixuan Chen ◽  
Decheng Ren ◽  
...  

Personality and subjective well-being (SWB) have been suggested to be strongly related in previous studies. This study was intended to confirm the relationship between personality and SWB and tried to seek out the genetic variants which underlie both personality and SWB. The subjects were 890 participants from Chinese Han population. We evaluated their personality using the Big Five Inventory (BFI) and used the Satisfaction With Life Scale (SWLS) to reflect their SWB. Five single nucleotide polymorphisms (SNPs) were selected from the literature (rs1426371, rs2164273, rs322931, rs3756290, rs490647) and genotyped for genetic association study. We found negative correlations between neuroticism and SWB. On the contrary, extraversion and agreeableness were positively associated with SWB. Three SNPs (rs2164273, rs3756290, rs490647) out of the five were found to connect with personality (extraversion, neuroticism, conscientiousness and openness to experience) and rs490647 variants of GRIK3 was also associated with SWB. Individuals carrying G allele at this site were predisposed to have lower risk to be neuroticism and greater chance to be extraverted, open and satisfied with their life. In summary, our study revealed that rs490647 might be a good candidate genetic variant for personality and SWB in Chinese Han population.


PLoS ONE ◽  
2017 ◽  
Vol 12 (4) ◽  
pp. e0175666 ◽  
Author(s):  
Lixia Fan ◽  
Linqi Chen ◽  
Xiaoling Ni ◽  
Shicheng Guo ◽  
Yinghui Zhou ◽  
...  

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