scholarly journals Increased Functional Connectivity Within and Between Cognitive-Control Networks from Early Infancy to Nine Years During Story Listening

2019 ◽  
Vol 9 (3) ◽  
pp. 285-295 ◽  
Author(s):  
Rola Farah ◽  
Tzipi Horowitz-Kraus
2006 ◽  
Vol 14 (7S_Part_16) ◽  
pp. P907-P907
Author(s):  
Gloria Benson ◽  
Andrea Hildebrandt ◽  
Catharina Lange ◽  
Theresa Köbe ◽  
Claudia Schwarz ◽  
...  

2020 ◽  
pp. 089198872096827
Author(s):  
Abhishek Jaywant ◽  
Larissa DelPonte ◽  
Dora Kanellopoulos ◽  
Michael W. O’Dell ◽  
Faith M. Gunning

Post-stroke depression and executive dysfunction co-occur and are highly debilitating. Few treatments alleviate both depression and executive dysfunction after stroke. Understanding the brain network changes underlying post-stroke depression with executive dysfunction can inform the development of targeted and efficacious treatment. In this review, we synthesize neuroimaging findings in post-stroke depression and post-stroke executive dysfunction and highlight the network commonalities that may underlie this comorbidity. Structural and functional alterations in the cognitive control network, salience network, and default mode network are associated with depression and executive dysfunction after stroke. Specifically, post-stroke depression and executive dysfunction are both linked to changes in intrinsic functional connectivity within resting state networks, functional over-connectivity between the default mode and salience/cognitive control networks, and reduced cross-hemispheric frontoparietal functional connectivity. Cognitive training and noninvasive brain stimulation targeted at these brain network abnormalities and specific clinical phenotypes may help advance treatment for post-stroke depression with executive dysfunction.


2020 ◽  
Author(s):  
Danielle D DeSouza ◽  
Samuel R Krimmel ◽  
Bharati M Sanjanwala ◽  
Addie Peretz ◽  
Vinod Menon ◽  
...  

Objective: To characterize the role of the amygdala in episodic (EM) and chronic (CM) migraine, we evaluated amygdala volumes, functional connectivity (FC), and associations with clinical and affective measures. Methods: Eighty-eight patients (44 with EM and 44 age- and sex-matched patients with CM) completed anatomical and resting-state functional MRI scans. Amygdala volumes and resting-state FC to three core large-scale cognitive control networks (default mode (DMN), salience (SN), central executive (CEN)) were compared between groups. Associations between amygdala volume and FC, measures of headache severity (frequency and intensity), and cognitive-affective measures (depression, anxiety, pain catastrophizing) were evaluated. Results: Compared to EM, patients with CM had larger amygdala volume bilaterally. Headache frequency and intensity were associated with increased left and right amygdala volume, and depression was associated with increased right amygdala volume. Patients with CM also demonstrated increased left amygdala FC with the DMN, which across patients was related to headache frequency. Left amygdala FC to the SN was correlated with headache intensity while right amygdala FC to the CEN was correlated with pain catastrophizing. Conclusion: Our findings reveal increased amygdala volume and FC with large-scale neurocognitive networks in patients with CM compared to EM. Aberrant amygdala volume and FC measures were associated with increased migraine severity, depression, and pain catastrophizing, pointing to a link between emotion and pain in migraine. Our findings provide novel insights into amygdala involvement in chronic migraine and may inform future interventions aimed at preventing the progression of both headache and its negative cognitive-affective symptoms.


2017 ◽  
Vol 39 (2) ◽  
pp. 811-821 ◽  
Author(s):  
Roger E. Beaty ◽  
Qunlin Chen ◽  
Alexander P. Christensen ◽  
Jiang Qiu ◽  
Paul J. Silvia ◽  
...  

2018 ◽  
Vol 10 (1) ◽  
Author(s):  
Gloria Benson ◽  
Andrea Hildebrandt ◽  
Catharina Lange ◽  
Claudia Schwarz ◽  
Theresa Köbe ◽  
...  

Cortex ◽  
2020 ◽  
Vol 132 ◽  
pp. 180-190
Author(s):  
Isabella A. Breukelaar ◽  
Kristi R. Griffiths ◽  
Anthony Harris ◽  
Sheryl L. Foster ◽  
Leanne M. Williams ◽  
...  

NeuroImage ◽  
2021 ◽  
pp. 118852
Author(s):  
Brittany K. Taylor ◽  
Michaela R. Frenzel ◽  
Jacob A. Eastman ◽  
Christine M. Embury ◽  
Oktay Acgaoglu ◽  
...  

2017 ◽  
Vol 121 (1) ◽  
pp. 93-111 ◽  
Author(s):  
Ryan Smith ◽  
Anna Alkozei ◽  
Jennifer Bao ◽  
William D. S. Killgore

The neural basis of suppressing conscious access to one’s own memories has recently received considerable attention, with several studies suggesting this process engages frontal-parietal cognitive control regions. However, researchers to date have not examined the way right and left hemisphere cognitive control networks coordinate with one another to accomplish this. We had 48 participants (25 female) complete a Think/No Think (T/NT) task for memories of emotionally unpleasant visual scenes while undergoing functional magnetic resonance imaging. We used generalized psychophysiologic interaction analyses to examine functional connectivity between right and left hemisphere frontal-parietal regions during memory suppression. Participants who were better at memory suppression, as assessed by greater numbers of forgotten memories in the NT than T conditions, also showed greater functional connectivity between multiple right and left hemisphere control regions. This suggests that individual differences in memory suppression ability may be partially explained by differences in task-specific inter-hemispheric coordination.


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