scholarly journals Brain networks of the imaginative mind: Dynamic functional connectivity of default and cognitive control networks relates to openness to experience

2017 ◽  
Vol 39 (2) ◽  
pp. 811-821 ◽  
Author(s):  
Roger E. Beaty ◽  
Qunlin Chen ◽  
Alexander P. Christensen ◽  
Jiang Qiu ◽  
Paul J. Silvia ◽  
...  
2017 ◽  
Author(s):  
Rosa Steimke ◽  
Jason S. Nomi ◽  
Vince D Calhoun ◽  
Christine Stelzel ◽  
Lena M. Paschke ◽  
...  

AbstractSelf-control and the ability to resist temptation are critical for successful completion of long-term goals. Contemporary models in cognitive neuroscience emphasize the primary role of prefrontal cognitive control networks in aligning behavior with such goals. Here we use gaze pattern analysis and dynamic functional connectivity fMRI data to explore how individual differences in the ability to resist temptation are related to intrinsic brain dynamics of the cognitive control and salience networks. Behaviorally, individuals exhibit greater gaze distance from target location (e.g. higher distractibility) during presentation of tempting erotic images compared with neutral images. Individuals whose intrinsic dynamic functional connectivity patterns gravitate towards configurations in which salience detection systems are less strongly coupled with visual systems resist tempting distractors more effectively. The ability to resist tempting distractors was not significantly related to intrinsic dynamics of the cognitive control network. These results suggest that susceptibility to temptation is governed in part by individual differences in salience network dynamics, and provide novel evidence for involvement of brain systems outside canonical cognitive control networks in contributing to individual differences in self-control.


2019 ◽  
Vol 29 (2) ◽  
Author(s):  
Yishul Wei ◽  
Jeanne Leerssen ◽  
Rick Wassing ◽  
Diederick Stoffers ◽  
Joy Perrier ◽  
...  

2006 ◽  
Vol 14 (7S_Part_16) ◽  
pp. P907-P907
Author(s):  
Gloria Benson ◽  
Andrea Hildebrandt ◽  
Catharina Lange ◽  
Theresa Köbe ◽  
Claudia Schwarz ◽  
...  

2012 ◽  
Vol 37 (8) ◽  
pp. 1923-1933 ◽  
Author(s):  
Ian H Harding ◽  
Nadia Solowij ◽  
Ben J Harrison ◽  
Michael Takagi ◽  
Valentina Lorenzetti ◽  
...  

2021 ◽  
Author(s):  
Xiang Xiao ◽  
Christopher Joseph Hammond ◽  
Betty Jo Salmeron ◽  
Hong Gu ◽  
Tianye Zhai ◽  
...  

The search for psychiatric biomarkers has remained elusive, in part, due to high comorbidity, low specificity, and poor concordance between neurobiological abnormalities and existing diagnostic categories. Developmental shifts in symptom expression and brain function across the lifespan further complicate biomarker identification. Recent studies suggest that focusing on cognition may be a pathway forward: Cognitive dysfunction is a common feature across psychiatric disorders. Individual differences in cognition may reflect variability in the connectivity of underlying neurocognitive brain networks, and predict psychopathology at different developmental periods. In the present study we identified brain-based dimensions of general cognitive capacity and psychopathology using sparse canonical correlation analysis (sCCA) in a sample of 7,383 preadolescents from the Adolescent Brian Cognitive Development (ABCD) study. This analysis revealed correlated patterns of functional connectivity with cognitive control capacity and psychopathology. Specifically, the results identified a single connectome-based latent brain variate that was positively correlated with performance on cognitive measures across domains and negatively correlated with parent-reported psychopathology across diagnoses and domains. Functional connectivity loadings for the brain variate were across distributed cortical and subcortical brain networks and a dose-dependent relationship with psychopathology based upon the cumulative number of psychiatric diagnoses was observed. These findings provide preliminary evidence for a connectome-based biomarker that indexes individual differences in cognitive control and predicts transdiagnostic psychopathology in a dose-dependent fashion.


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