scholarly journals Reduced Levels and Bioactivity of Endogenous Protease Cathepsin D in Genital Tract Secretions of Postmenopausal Women

2017 ◽  
Vol 33 (5) ◽  
pp. 407-409 ◽  
Author(s):  
Mariel Jais ◽  
Naji Younes ◽  
Stacey Chapman ◽  
Susan Cu-Uvin ◽  
Mimi Ghosh
Keyword(s):  
Postmenopausal Women ◽  
Genital Tract ◽  
Cathepsin D ◽  
Endogenous Protease

scholarly journals Human papillomavirus infection rate, distribution characteristics, and risk of age in pre- and postmenopausal women

2020 ◽  
Author(s):  
Yan Shen ◽  
Jing Xia ◽  
Hui hui Li ◽  
Yang Xu ◽  
San ping Xu
Keyword(s):  
Cervical Cancer ◽  
High Risk ◽  
Postmenopausal Women ◽  
Infection Rate ◽  
Genital Tract ◽  
Hpv Infection ◽  
Distribution Characteristics ◽  
Lower Genital Tract ◽  
Significant Difference ◽  
High Risk Hpv

Abstract BackgroundThe incidence rate of cervical cancer is increasing yearly. The persistent infection of high-risk Human Papillomavirus (HPV) is the main factor leading to cervical cancer. HPV infection is double peak type. This study aimed at analyzing the HPV distribution characteristics, infection rate, and risk of age in pre- and postmenopausal women. So as to provide reference for the prevention of HPV infection and cervical cancer screening strategy.MethodsA retrospective analysis of 4614 women who underwent cervical cytology, and HPV examination from January 2018 to October 2019 at the healthcare department of Wuhan Union Hospital was done. We explored the characteristics and distribution of HPV infections around the menopause, then comparing the infection rate of HPV in postmenopause and over 65 years old, in order to analyze the influence of different ages on HPV infection.ResultsGenerally, the HPV infection rate was 13.10% (539 / 4115), whereby the high-risk subtype constituted 73.84% (398 / 539) of all positive cases. On the other hand, the HPV39 infection was more common in postmenopausal women; however, there was no significant difference in the distribution of the other types in the pre- and postmenopausal women (Insert p value). The first four subtypes were 52 / 53 / 58 / 16, respectively. The infection rate of HPV in patients with lower genital tract inflammation was significantly higher, P = 0.000, 95% CI: 1.911 (1.416, 2.580) compared with those without lower genital tract inflammation. The results further showed that there was no significant difference between pre- and postmenopausal women in terms of HPV infection rate, but more susceptible to high-risk HPV infection after the age of 65 (P = 0.041). Except for 40 years old to menopause, the infection rate of high-risk HPV in this age group was different from that in postmenopause(P = 0.023,0.729(0.555,0.957)), other age groups had no significant effect on high-risk HPV infection.ConclusionsIt was concluded that whether menopause has nothing to do with HPV infection. Moreover, the infection rate of high-risk HPV increases after 65 years of age; hence the cutoff screening age should be appropriately prolonged.Trial registration: Retrospectively registered.

Alterations in Genital Tract Soluble Immune Mediators in HIV Positive Postmenopausal Women: Implications for HIV Acquisition and Transmission

2014 ◽  
Vol 30 (S1) ◽  
pp. A231-A231
Author(s):  
Josie Delisle ◽  
Ifeyinwa Benyeogor ◽  
Mariel Jais ◽  
Naji Younes ◽  
Mary Young ◽  
...  
Keyword(s):  
Postmenopausal Women ◽  
Genital Tract ◽  
Hiv Positive ◽  
Immune Mediators ◽  
Hiv Acquisition

scholarly journals Dysregulation in Genital Tract Soluble Immune Mediators in Postmenopausal Women Is Distinct by HIV Status

2019 ◽  
Vol 35 (3) ◽  
pp. 251-259
Author(s):  
Mimi Ghosh ◽  
Mariel Jais ◽  
Josie Delisle ◽  
Naji Younes ◽  
Ifeyinwa Benyeogor ◽  
...  
Keyword(s):  
Postmenopausal Women ◽  
Genital Tract ◽  
Hiv Status ◽  
Immune Mediators

scholarly journals Verrucous Carcinoma of the Vulva: A Case Report

2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Ioannis Boutas ◽  
Chrisostomos Sofoudis ◽  
Emmanouil Kalampokas ◽  
Christos Anastasopoulos ◽  
Theodoros Kalampokas ◽  
...  
Keyword(s):  
Case Report ◽  
Postmenopausal Women ◽  
Genital Tract ◽  
Verrucous Carcinoma ◽  
Female Genital Tract ◽  
University Hospital ◽  
Specialist Doctor ◽  
Rare Lesion ◽  
Female Genital

Verrucous carcinoma of the female genital tract is a rare lesion, primarily affecting postmenopausal women. We present a 78-year-old patient with verrucous carcinoma of the vulva, who was admitted to the “Aretaieion” Athens University Hospital. She had complained of vulvar itching during the last two years without visiting a specialist doctor.

scholarly journals Analysis of Genital Tract Malignancies in Postmenopausal Indian Women

2013 ◽  
Vol 1 (2) ◽  
pp. 66-69
Author(s):  
Sulabha Joshi ◽  
Sheela Jain ◽  
Anjali Kawthalkar ◽  
Savita A Somalwar ◽  
Ashutosh Somalwar
Keyword(s):  
Ovarian Carcinoma ◽  
Postmenopausal Women ◽  
South Asian ◽  
Genital Tract ◽  
Cross Sectional Study ◽  
Carcinoma Cervix ◽  
Cross Sectional ◽  
Indian Women ◽  
Carcinoma Endometrium ◽  
Carcinoma Ovary

ABSTRACT Introduction Genital malignancies in women varies widely from developed to developing countries. Postmenopausal women are at risk of developing various genital malignancies. Objectives (1) To determine frequency of genital tract malignancies in postmenopausal women, (2) to determine the type and stage of genital tract malignancies, (3) to create awareness of screening in women. Materials and methods This descriptive cross-sectional study was carried out over a period of 2 years from March 2010 to Feb. 2012. It included 200 postmenopausal women admitted with complaints like mass or fullness of abdomen, bleeding or discharge per vaginal and ulcer over vulva. They were evaluated clinically followed by relevant investigations. Malignancy was confirmed by histopathology report. Results Out of 200 postmenopausal women admitted during study period, malignancy was confirmed in 55 women (27.5%). The type of malignancy was cervical carcinoma (30, 54.54%), ovarian carcinoma (18, 32.72%), carcinoma endometrium (5, 9.09%), carcinoma vulva (1, 1.81%) and carcinoma vagina (1, 1.81%). Majority of carcinoma cervix and ovarian carcinoma were in advanced stage. Conclusion Carcinoma cervix was commonest genital malignancy found our study followed by carcinoma ovary. Importance of routine gynecological check-up in postmenopausal women was emphasised. How to cite this article Somalwar SA, Joshi S, Kawthalkar A, Bhalerao A, Jain S, Somalwar A. Analysis of Genital Tract Malignancies in Postmenopausal Indian Women. J South Asian Feder Menopause Soc 2013;1(2):66-69.

scholarly journals Vaginal stenosis with cervical intraepithelial neoplasia in a postmenopausal patient with pyometra: a diagnostic dilemma

2020 ◽  
Vol 9 (2) ◽  
pp. 842
Author(s):  
Jenifer Ahmad ◽  
Meena N. Satia ◽  
V. R. Badhwar
Keyword(s):  
Cervical Intraepithelial Neoplasia ◽  
Postmenopausal Women ◽  
Genital Tract ◽  
Intraepithelial Neoplasia ◽  
Malignant Diseases ◽  
Diagnostic Dilemma ◽  
Postmenopausal Patient ◽  
Vaginal Stenosis ◽  
Gynaecological Malignancy ◽  
Child Bearing

Postmenopausal patient presenting with pain and lump in abdomen should be considered as a complication caused by gynaecological malignancy unless proved otherwise pyometra is most common in postmenopausal women but it can affect women of child bearing age as well. Usually it is caused by impairment of natural drainage of the cervix due to malignant diseases of genital tract and consequences of their treatment with radiotherapy. Authors report one such case with cervical intraepithelial neoplasia with uterus markedly enlarged to 26-28 weeks size with Vaginal stenosis in an eighty-year-old postmenopausal patient.

Long term effects of tibolone on the genital tract in postmenopausal women

1999 ◽  
Vol 106 (9) ◽  
pp. 954-959 ◽  
Author(s):  
E. P. Morris ◽  
P. O. G. Wilson ◽  
J. Robinson ◽  
J. M. Rymer
Keyword(s):  
Postmenopausal Women ◽  
Genital Tract ◽  
Long Term Effects

Reduced levels of genital tract immune biomarkers in postmenopausal women: implications for HIV acquisition

2016 ◽  
Vol 215 (3) ◽  
pp. 324.e1-324.e10 ◽  
Author(s):  
Mariel Jais ◽  
Naji Younes ◽  
Stacey Chapman ◽  
Susan Cu-Uvin ◽  
Mimi Ghosh
Keyword(s):  
Postmenopausal Women ◽  
Genital Tract ◽  
Immune Biomarkers ◽  
Hiv Acquisition

Effects of ospemifene and raloxifene on hormonal status, lipids, genital tract, and tolerability in postmenopausal women

2005 ◽  
Vol 12 (2) ◽  
pp. 202-209 ◽  
Author(s):  
Janne Komi ◽  
Kari S. Lankinen ◽  
Pirkko H??rk??nen ◽  
Michael W. DeGregorio ◽  
Sari Voipio ◽  
...  
Keyword(s):  
Postmenopausal Women ◽  
Genital Tract ◽  
Hormonal Status
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