scholarly journals Acute Restraint Stress Alters Wheel-Running Behavior Immediately Following Stress and up to 20 Hours Later in House Mice

2016 ◽  
Vol 89 (6) ◽  
pp. 546-552 ◽  
Author(s):  
Jessica L. Malisch ◽  
Karen deWolski ◽  
Thomas H. Meek ◽  
Wendy Acosta ◽  
Kevin M. Middleton ◽  
...  
2001 ◽  
Vol 120 (5) ◽  
pp. A715-A715
Author(s):  
A ROSZTOCZY ◽  
S BRADESI ◽  
C BEAUFRAND ◽  
J FIORAMONTI ◽  
T WITTMANN ◽  
...  

2016 ◽  
Vol 28 (4) ◽  
pp. 239-243 ◽  
Author(s):  
Ana Belén Segarra ◽  
Joaquín Hernández ◽  
Isabel Prieto ◽  
Marc de Gasparo ◽  
Manuel Ramírez-Sánchez

ObjectiveTo evaluate the influence of acute restraint stress (ARS) on plasma enkephalinase and oxytocinase activities. ARS modifies basal activities in cortico-limbic regions of rats and induces changes in the correlations observed between these regions. The interactions between plasma and cortico-limbic activities will be also evaluated.MethodsEnkephalinase (AlaAP and LeuAP) and oxytocinase (P-LeuAP) activities were fluorometrically determined in plasma of control and stressed rats using aminoacyl-β-naphthylamides (aaNNap), AlaNNap and LeuNNap as substrates.ResultsNo differences in enzymatic activities were observed between control and stressed animals in plasma. In contrast, highly significant positive and negative correlations between plasma and cortico-limbic regions were demonstrated in controls. Stress conditions significantly alter the pattern of these correlations.ConclusionThe present results clearly support a connection between plasma and brain involving certain neuropeptidase activities that change under stress conditions.


Neuroscience ◽  
2014 ◽  
Vol 258 ◽  
pp. 364-373 ◽  
Author(s):  
T.B. Moraes-Neto ◽  
A.A. Scopinho ◽  
C. Biojone ◽  
F.M.A. Corrêa ◽  
L.B.M. Resstel

1985 ◽  
Vol 248 (2) ◽  
pp. R181-R189 ◽  
Author(s):  
J. L. Blank ◽  
C. Desjardins

The reproductive responses of two species of wild rodents, house mice and deer mice, were evaluated following a 30% reduction in food intake for 5 wk. These animal models were chosen as prototypes of other rodent species because each employs unique functional adjustments when confronted with reduced resources in their natural habitats. Modest inanition failed to alter pituitary-testicular function in house mice; neither spermatogenesis nor plasma concentrations of luteinizing hormone (LH) and testosterone were modified. In sharp distinction, deer mice exposed to restricted food intake showed significant reductions in plasma LH and testosterone and an accompanying loss in spermatogenesis. Reduced food intake also caused pronounced shifts in the temporal organization and amount of wheel-running activity in both animal models, albeit in a dichotomous fashion. House mice exhibited the same amount of wheel-running activity throughout inanition, but the diel periodicity of locomotor behavior was shifted from the dark to the light period. Deer mice, in comparison, significantly curtailed wheel-running activity during the dark hours but ran in precise phase relationship with the light-dark cycle. Taken together, our results establish that the male reproductive system and its supporting neuroendocrine and behavioral correlates can be disrupted by modest levels of food restriction in certain animal models.


2020 ◽  
Vol 238 (1) ◽  
pp. 259-269
Author(s):  
Sajedeh Mosaffa ◽  
Hanieh Ahmadi ◽  
Fatemeh Khakpai ◽  
Mohaddeseh Ebrahimi-Ghiri ◽  
Mohammad-Reza Zarrindast

2020 ◽  
Vol 21 (21) ◽  
pp. 8136
Author(s):  
Ramona D’Amico ◽  
Rosalba Siracusa ◽  
Roberta Fusco ◽  
Marika Cordaro ◽  
Tiziana Genovese ◽  
...  

Stress is generally defined as a homeostatic disruption from actual or implied threats and alters the homeostatic balance of different body organs, such as gastrointestinal function and the hypothalamic-pituitary-adrenal axis (HPA), inducing the release of glucocorticoid hormones. Stress is also known to be a risk factor for the development of depression and anxiety. However, until today there are no suitable therapies for treating of stress. The aim of this study was to explore the protective effect of Colomast®, a new preparation containing Adelmidrol, an enhancer of physiological of palmitoylethanolamide (PEA), and sodium hyaluronate in an animal model of immobilization stress. Acute restraint stress (ARS) was induced in mice by fixation for 2 h of the four extremities with an adhesive tape and Colomast® (20 mg/kg) was administered by oral gavage 30 min before the immobilization. Colomast® pre-treatment was able to decrease histopathological changes in the gastrointestinal tract, cytokines expression, neutrophil infiltration, mast cell activation, oxidative stress, as well as modulate nuclear factor NF-kB and apoptosis pathways after ARS induction. Moreover, Colomast® was able to restore tight junction in both ileum and hippocampus and cortex. Additionally, we demonstrated that Colomast® ameliorated depression and anxiety-related behaviours, and modulate inflammatory and apoptosis pathways also in brain after ARS induction. In conclusion, our results suggest Colomast® to be a potential approach to ARS.


2019 ◽  
Vol 149 ◽  
pp. 184-193
Author(s):  
Bo-Xuan Tu ◽  
Lai-Fa Wang ◽  
Xiao-Lin Zhong ◽  
Zhao-Lan Hu ◽  
Wen-Yu Cao ◽  
...  

2014 ◽  
Vol 40 ◽  
pp. e24
Author(s):  
A.N. de Lima ◽  
E.K. Hamasato ◽  
D.G. da Cruz ◽  
J. Palermo-Neto ◽  
C.O. Massoco

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