Critical Gaps in Knowledge of the Epidemiology and Pathophysiology of Healthcare-Associated Infections

2010 ◽  
Vol 31 (S1) ◽  
pp. S4-S6 ◽  
Author(s):  
David K. Henderson ◽  
Tara N. Palmore

The past decade has witnessed an intense interest in healthcare-associated infections as well as increases in legislation and reporting requirements aimed at decreasing the number of these costly infections. In the next decade, healthcare epidemiology must address major gaps in understanding of the epidemiology and pathogenesis of healthcare-associated infections and in knowledge of the efficacy of interventions for healthcare-associated infections and the efficacy in implementing such interventions.

2019 ◽  
Vol 40 (8) ◽  
pp. 904-909 ◽  
Author(s):  
Isabelle Vock ◽  
Sarah Tschudin-Sutter

AbstractIn the past several decades, the incidence of Klebsiella pneumoniae harboring resistance mechanisms against multiple antibiotic agents has increased on a global scale. We discuss reasons for ongoing transmission of multidrug-resistant K. pneumoniae in healthcare settings, which has resulted in the successful spread and establishment of this pathogen. It is now one of the most important causes of healthcare-associated infections worldwide.


2012 ◽  
Vol 22 (12) ◽  
pp. 383-388
Author(s):  
Angela Cobbold ◽  
Sue Lord

In the United States, approximately 46.5 million surgical and medical procedures, including approximately 5 million gastrointestinal endoscopies are performed annually (Rutala & Weber 2008). In contrast, there are some 4.2 million surgical operations carried out annually in England (RCS 2012). The majority of these procedures involve patient contact with reusable invasive medical devices (RIMDs). Over the past 15 years, there have been significant changes in guidance and legislation relating to decontamination processes, mainly resulting from the focus on variant Creutzfeldt-Jakob disease (vCJD) (NSH 2001, DH 2003) and the need to tackle increasing problems with healthcare associated infections (HCAIs). Therefore, with approximately 350 NHS hospitals in England alone (RCS 2012), there is potential for a major risk of cross contamination for patients and staff.


2014 ◽  
Vol 35 (S2) ◽  
pp. S48-S65 ◽  
Author(s):  
Erik R. Dubberke ◽  
Philip Carling ◽  
Ruth Carrico ◽  
Curtis J. Donskey ◽  
Vivian G. Loo ◽  
...  

Previously published guidelines are available that provide comprehensive recommendations for detecting and preventing healthcare-associated infections (HAIs). The intent of this document is to highlight practical recommendations in a concise format designed to assist acute care hospitals in implementing and prioritizing their Clostridium difficile infection (CDI) prevention efforts. This document updates “Strategies to Prevent Clostridium difficile Infections in Acute Care Hospitals,” published in 2008. This expert guidance document is sponsored by the Society for Healthcare Epidemiology of America (SHEA) and is the product of a collaborative effort led by SHEA, the Infectious Diseases Society of America (IDSA), the American Hospital Association (AHA), the Association for Professionals in Infection Control and Epidemiology (APIC), and The Joint Commission, with major contributions from representatives of a number of organizations and societies with content expertise. The list of endorsing and supporting organizations is presented in the introduction to the 2014 updates.


2020 ◽  
Vol 6 (3) ◽  
pp. 185
Author(s):  
Elizabete de Souza Cândido ◽  
Flávia Affonseca ◽  
Marlon Henrique Cardoso ◽  
Octavio Luiz Franco

Candida auris has been reported in the past few years as an invasive fungal pathogen of high interest. Its recent emergence in healthcare-associated infections triggered the efforts of researchers worldwide, seeking additional alternatives to the use of traditional antifungals such as azoles. Lipopeptides, specially the echinocandins, have been reported as an effective approach to control pathogenic fungi. However, despite its efficiency against C. auris, some isolates presented echinocandin resistance. Thus, therapies focused on echinocandins’ synergism with other antifungal drugs were widely explored, representing a novel possibility for the treatment of C. auris infections.


2014 ◽  
Vol 35 (S2) ◽  
pp. S66-S88 ◽  
Author(s):  
Deverick J. Anderson ◽  
Kelly Podgorny ◽  
Sandra I. Berríos-Torres ◽  
Dale W. Bratzler ◽  
E. Patchen Dellinger ◽  
...  

Previously published guidelines are available that provide comprehensive recommendations for detecting and preventing healthcare-associated infections (HAIs). The intent of this document is to highlight practical recommendations in a concise format designed to assist acute care hospitals in implementing and prioritizing their surgical site infection (SSI) prevention efforts. This document updates “Strategies to Prevent Surgical Site Infections in Acute Care Hospitals,” published in 2008. This expert guidance document is sponsored by the Society for Healthcare Epidemiology of America (SHEA) and is the product of a collaborative effort led by SHEA, the Infectious Diseases Society of America (IDSA), the American Hospital Association (AHA), the Association for Professionals in Infection Control and Epidemiology (APIC), and The Joint Commission, with major contributions from representatives of a number of organizations and societies with content expertise. The list of endorsing and supporting organizations is presented in the introduction to the 2014 updates.


F1000Research ◽  
2019 ◽  
Vol 8 ◽  
pp. 106
Author(s):  
Pranavi Sreeramoju

Since the 2014 publication of updates to the Society for Healthcare Epidemiology of America (SHEA) compendium of strategies to reduce healthcare-associated infections, there have been several advances in understanding the epidemiology of these diseases. This review article captures many of the key advances but does not include all of them.


2010 ◽  
Vol 31 (S1) ◽  
pp. S70-S72 ◽  
Author(s):  
Arjun Srinivasan

Outbreaks of healthcare-associated infections have long played a critical role in both identification and mitigation of emerging challenges in health care. This article describes some of the most influential outbreaks of healthcare-associated infections in the past decade that serve as excellent illustrations of this point.


2010 ◽  
Vol 31 (S1) ◽  
pp. S18-S21 ◽  
Author(s):  
Aaron M. Milstone ◽  
Kristina A. Bryant ◽  
W. Charles Huskins ◽  
Danielle M. Zerr

Multidrug resistant organisms (MDROs) and healthcare-associated infections (HAIs) are associated with increased lengths of hospital stay, increased costs, and increased mortality. We explore the scope of MDRO HAIs in children, current MDRO HAI prevention practices and data to support these practices, and we propose research topics targeting MDRO HAI prevention in children.


2020 ◽  
Vol 5 (6) ◽  
pp. 276-280
Author(s):  
Karen Jenkins

Over the past 9 months, hand hygiene has been highlighted as one of the key elements in the prevention of the spread of COVID-19, and health professionals know that hands play a key role in the transmission of infection. People with chronic kidney disease are particularly susceptible to healthcare-associated infections, so everyone coming into contact with these vulnerable people needs to be able to perform the relevant hand hygiene procedures correctly and appropriately to protect patients and themselves


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