scholarly journals Widespread Dissemination of a Drug‐Susceptible Strain ofMycobacterium tuberculosis

1997 ◽  
Vol 176 (2) ◽  
pp. 478-484 ◽  
Author(s):  
Cindy R. Friedman ◽  
Geoff C. Quinn ◽  
Barry N. Kreiswirth ◽  
David C. Perlman ◽  
Nadim Salomon ◽  
...  
Keyword(s):  
Susceptible Strain ◽  
Ofmycobacterium Tuberculosis ◽  
Strain Ofmycobacterium ◽  
Widespread Dissemination

scholarly journals Truncated Structural Variants of Lipoarabinomannan inMycobacterium lepraeand an Ethambutol-resistant Strain ofMycobacterium tuberculosis

2004 ◽  
Vol 279 (39) ◽  
pp. 41227-41239 ◽  
Author(s):  
Jordi B. Torrelles ◽  
Kay-Hooi Khoo ◽  
Peter A. Sieling ◽  
Robert L. Modlin ◽  
Nannan Zhang ◽  
...  
Keyword(s):  
Resistant Strain ◽  
Structural Variants ◽  
Ofmycobacterium Tuberculosis ◽  
Strain Ofmycobacterium

scholarly journals Spread of Strain W, a Highly Drug‐Resistant Strain ofMycobacterium tuberculosis, Across the United States

1999 ◽  
Vol 29 (1) ◽  
pp. 85-92 ◽  
Author(s):  
Tracy B. Agerton ◽  
Sarah E. Valway ◽  
Richard J. Blinkhorn ◽  
Kenneth L. Shilkret ◽  
Randall Reves ◽  
...  
Keyword(s):  
United States ◽  
Resistant Strain ◽  
The United States ◽  
Drug Resistant ◽  
Ofmycobacterium Tuberculosis ◽  
Strain Ofmycobacterium

An Outbreak Involving Extensive Transmission of a Virulent Strain ofMycobacterium tuberculosis

1998 ◽  
Vol 338 (10) ◽  
pp. 633-639 ◽  
Author(s):  
Sarah E. Valway ◽  
Maria Pia C. Sanchez ◽  
Thomas F. Shinnick ◽  
Ian Orme ◽  
Tracy Agerton ◽  
...  
Keyword(s):  
Virulent Strain ◽  
Ofmycobacterium Tuberculosis ◽  
Strain Ofmycobacterium

Differential carriage of virulence-associated loci in the New Zealand Rangipo outbreak strain ofMycobacterium tuberculosis

2017 ◽  
Vol 49 (9) ◽  
pp. 680-688 ◽  
Author(s):  
Sanjay S. Gautam ◽  
Micheál Mac Aogáin ◽  
James E. Bower ◽  
Indira Basu ◽  
Ronan F. O’Toole
Keyword(s):  
New Zealand ◽  
Outbreak Strain ◽  
Ofmycobacterium Tuberculosis ◽  
Strain Ofmycobacterium

scholarly journals Insecticide resistance status of malaria vectors Anopheles gambiae (s.l.) of southwest Burkina Faso and residual efficacy of indoor residual spraying with microencapsulated pirimiphos-methyl insecticide

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Dieudonné Diloma Soma ◽  
Barnabas Zogo ◽  
Domonbabele François de Sales Hien ◽  
Aristide Sawdetuo Hien ◽  
Didier Alexandre Kaboré ◽  
...  
Keyword(s):  
Insecticide Resistance ◽  
Burkina Faso ◽  
Anopheles Gambiae ◽  
Local Population ◽  
Residual Activity ◽  
Indoor Residual Spraying ◽  
Susceptible Strain ◽  
Malaria Vectors ◽  
Pirimiphos Methyl ◽  
Residual Efficacy

Abstract Background The rapid spread of insecticide resistance in malaria vectors and the rebound in malaria cases observed recently in some endemic areas underscore the urgent need to evaluate and deploy new effective control interventions. A randomized control trial (RCT) was conducted with the aim to investigate the benefit of deploying complementary strategies, including indoor residual spraying (IRS) with pirimiphos-methyl in addition to long-lasting insecticidal nets (LLINs) in Diébougou, southwest Burkina Faso. Methods We measured the susceptibility of the Anopheles gambiae (s.l.) population from Diébougou to conventional insecticides. We further monitored the efficacy and residual activity of pirimiphos-methyl on both cement and mud walls using a laboratory susceptible strain (Kisumu) and the local An. gambiae (s.l.) population. Results An. gambiae (s.l.) from Diébougou was resistant to DDT, pyrethroids (deltamethrin, permethrin and alphacypermethrin) and bendiocarb but showed susceptibility to organophosphates (pirimiphos-methyl and chlorpyrimiphos-methyl). A mixed-effect generalized linear model predicted that pirimiphos-methyl applied on cement or mud walls was effective for 210 days against the laboratory susceptible strain and 247 days against the local population. The residual efficacy of pirimiphos-methyl against the local population on walls made of mud was similar to that of cement (OR = 0.792, [0.55–1.12], Tukey’s test p-value = 0.19). Conclusions If data on malaria transmission and malaria cases (as measured trough the RCT) are consistent with data on residual activity of pirimiphos-methyl regardless of the type of wall, one round of IRS with pirimiphos-methyl would have the potential to control malaria in a context of multi-resistant An. gambiae (s.l.) for at least 7 months.

scholarly journals Polygenic and single gene responses to selection for resistance to diazinon in Lucilia cuprina.

Genetics ◽  
1992 ◽  
Vol 130 (3) ◽  
pp. 613-620 ◽  
Author(s):  
J A McKenzie ◽  
A G Parker ◽  
J L Yen
Keyword(s):  
Resistant Strain ◽  
Single Gene ◽  
Natural Populations ◽  
Susceptible Strain ◽  
Selection Line ◽  
Base Population ◽  
Gene Response ◽  
Biochemical Profiles ◽  
Resistant Strains ◽  
Selection For

Abstract Following mutagenesis with ethyl methanesulfonate, selection in a susceptible strain with a concentration of the insecticide diazinon (0.0004%, w/v) above that required to kill 100% of the susceptible strain, the LC100 of that strain, resulted in a single gene response. The resultant four mutant resistant strains have equivalent physiological, genetical and biochemical profiles to a diazinon-resistant strain derived from a natural population and homozygous for the Rop-1 allele. Modification of the microsomal esterase E3 is responsible for resistance in each case. The Rop-1 locus maps approximately 4.4 map units proximal to bu on chromosome IV. Selection within the susceptible distribution, at a concentration of diazinon [0.0001% (w/v)] less than the LC100, resulted in a similar phenotypic response irrespective of whether the base population had been mutagenized. The responses were polygenically based, unique to each selection line and independent of Rop-1. The relevance of the results to selection for insecticide resistance in laboratory and natural populations is discussed.

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