Tuberculin Skin Testing Among Healthcare Workers in the University of Malaya Medical Centre, Kuala Lumpur, Malaysia

2002 ◽  
Vol 23 (10) ◽  
pp. 584-590 ◽  
Author(s):  
Lian-HuatTan ◽  
Adeeba Kamarulzaman ◽  
Chong-Kin Iiam ◽  
Toong-Chow Lee
Keyword(s):  
Confidence Interval ◽  
Odds Ratio ◽  
Healthcare Workers ◽  
Skin Testing ◽  
Medical Centre ◽  
Tuberculin Skin Testing ◽  
Kuala Lumpur ◽  
Bacille Calmette Guerin ◽  
High Prevalence ◽  
The University

Objectives:To determine the occupational risk of Mycobacterium tuberculosis infection among healthcare workers (HCWs) and to examine the utility of tuberculin skin testing in a developing country with a high prevalence of bacille Calmette-Guerin vaccination.Design:Tuberculin skin test (TST) survey.Setting:A tertiary-care referral center and a teaching hospital in Kuala Lumpur, Malaysia.Participants:HCWs from medical, surgical, and orthopedic wards.Intervention:Tuberculin purified protein derivative RT-23 (State Serum Institute, Copenhagen, Denmark) was used for the TST (Mantoux method).Results:One hundred thirty-seven (52.1%) and 69 (26.2%) of the HCWs tested had indurations of 10 mm or greater and 15 mm or greater, respectively. Medical ward HCWs were at significantly higher risk of a positive TST reaction than were surgical or orthopedic ward HCWs (odds ratio, 2.18; 95% confidence interval, 1.33 to 3.57; P = .002 for TST positivity at 10 mm or greater) (odds ratio, 2.61; 95% confidence interval, 1.44 to 4.70; P = .002 for TST positivity at 15 mm or greater). A previous TST was a significant risk factor for a positive TST reaction at either 10 mm or greater or 15 mm or greater, but a duration of employment of more than 1 year and being a nurse were only significantly associated with a positive TST reaction at a cut-off point of 15 mm or greater.Conclusions:HCWs at the University of Malaya Medical Centre had an increased risk for M. tuberculosis infection that was significantly associated with the level of occupational tuberculosis exposure. A TST cut-off point of 15 mm or greater may correlate better with M. tuberculosis infection than a cut-off point of 10 mm or greater in settings with a high prevalence of bacille Calmette-Guerin vaccination (Infect Control Hosp Epidemiol 2002;23:584-590).

scholarly journals Knowledge, attitude, and practice of healthcare workers toward COVID-19 and its prevention in Ethiopia: A multicenter study

2021 ◽  
Vol 9 ◽  
pp. 205031212110343
Author(s):  
Bedru Jemal ◽  
Zemedu Aweke ◽  
Simeneh Mola ◽  
Sileshi Hailu ◽  
Sileshi Abiy ◽  
...  
Keyword(s):  
Social Media ◽  
Confidence Interval ◽  
Odds Ratio ◽  
Healthcare Workers ◽  
Medical Illness ◽  
Chronic Medical Illness ◽  
Attitude And Practice ◽  
Route Of Transmission ◽  
History Of ◽  
Knowledge Attitude And Practice

Background: An emerging respiratory disease abbreviated as coronavirus disease 2019 was first reported in December 2019 in Wuhan city of China. The virus is zoonotic and tends to be transmitted between animals to humans and humans to humans. The major route of transmission of coronavirus disease 2019 is droplet and close contact. The Ethiopian Ministry of Health has initiated training for health care workers at a different level. Thus, the main objective of this study is to assess the knowledge, attitudes, and practices of health workers in Ethiopia toward coronavirus disease 2019 and its prevention techniques. Method: An institution-based multicenter cross-sectional study was conducted in each of eight teaching and referral hospitals. A total of 422 Ethiopian healthcare workers were selected for the assessment of knowledge, attitude, and practice toward coronavirus disease 2019. Data were collected using a structured questionnaire. A logistic regression model was used to identify factors associated with the attitude and knowledge of healthcare workers toward coronavirus disease 2019 at a significance level of p < 0.05. Result: Three hundred ninety-seven healthcare workers participated in the study, with a response rate of 94%. Among these, 88.2% and 94.7% of respondents had good knowledge and positive attitudes, respectively. A respondent with a history of chronic medical illness (odds ratio: 0.193, 95% confidence interval: 0.063–0.593), social media, telecommunication, and television/radio as a source of information were significantly associated with knowledge (odds ratio: 3.4, 95% confidence interval: 1.5–7.4, OR: 4.3, 95% confidence interval: 1.3–14.3 and odds ratio: 3.2, 95% confidence interval: 1.4–7.2). In addition, respondents with a history of chronic medical illness were significantly associated with a negative attitude toward coronavirus disease 2019. Conclusion: The knowledge and attitude were good while; the practice was relatively low. Sources of information such as social media, telecommunication, and television/radio were positively associated with healthcare workers' knowledge about coronavirus disease 2019.

scholarly journals The Incidence of Non-Tuberculous Mycobacteria in Infants in Kenya

2019 ◽  
Vol 2019 ◽  
pp. 1-10 ◽  
Author(s):  
Grace Kaguthi ◽  
Videlis Nduba ◽  
Wilfred Murithi ◽  
Suzanne Verver
Keyword(s):  
Risk Factors ◽  
Lung Disease ◽  
Hiv Testing ◽  
Chest Radiography ◽  
Odds Ratio ◽  
Clinical Characteristics ◽  
Skin Testing ◽  
American Thoracic Society ◽  
Tuberculin Skin Testing ◽  
Western Kenya

There is inadequate understanding of the epidemiology of Non-Tuberculous Mycobacteria (NTM) among infants in high tuberculosis burden countries. The objective of this study was to document the incidence and diversity of NTM disease or colonisation in sputum specimens from infants with presumptive TB, the risk factors, and clinical characteristics, in a high TB and HIV burden setting in Western Kenya. A cohort of 2900 newborns was followed for 1–2 years to assess TB incidence. TB investigations included collection of induced sputa and gastric aspirates for culture and speciation by HAIN®, Tuberculin Skin Testing (TST), HIV testing, and chest radiography. The American Thoracic Society Criteria (ATS) were applied to identify NTM disease. Among 927 (32% of 2900) with presumptive TB, 742 (80%) were investigated. NTM were isolated from 19/742 (2.6%) infants. M. fortuitum was most frequently speciated (32%). Total person-time was 3330 years. NTM incidence was 5.7/1,000 person-years, 95% CI (3.5, 8.7). Infants diagnosed with TB were more likely to have NTM isolation (odds ratio 11.5; 95% CI 3.25, 41.0). None of the infants with NTM isolated met the criteria for NTM disease. The incidence of NTM isolation was comparable to similar studies in Africa. NTM isolation did not meet ATS criteria for disease and could represent colonisation. TB disease appears to be structural lung disease predisposing to NTM colonisation.

Tuberculosis in Hemodialysis Patients in New Jersey: A Statewide Study

1999 ◽  
Vol 20 (9) ◽  
pp. 607-609 ◽  
Author(s):  
Teresa A. Simon ◽  
Sindy Paul ◽  
Daniel Wartenberg ◽  
Jerome I. Tokars
Keyword(s):  
New Jersey ◽  
Infection Control ◽  
Healthcare Workers ◽  
Skin Testing ◽  
Hemodialysis Patients ◽  
Chronic Hemodialysis ◽  
Tuberculin Skin Testing ◽  
Control Policies ◽  
Newly Hired ◽  
Tb Infection Control

AbstractObjective:To study the incidence of tuberculosis (TB), tuberculin skin testing (TST) practices, and infection control practices at outpatient hemodialysis centers.Design:Mail surveys performed in December 1994 and 1995.Main Outcome Measures:The numbers of patients with incident active TB during 1994 and 1995, TST policies during 1994, and TB infection control policies in 1994.Setting:All outpatient dialysis centers in New Jersey.Patients or Participants:Healthcare workers and patients in dialysis centers in New Jersey.Results:Of 47 centers, 41 provided information on TST and TB infection control policies and practices. TSTs were performed on newly hired healthcare workers at all 41 centers and on established workers at 39 centers. In contrast, only 1 center reported performing TSTs on hemodialysis patients; 5 other centers reported screening of patients for TB using chest radiographs. Active TB was reported in 3 of 4,550 chronic hemodialysis patients in 1994 (rate, 66/100,000 patient-years) and in 4 of 4,831 patients in 1995 (rate, 83/100,000 patient-years). Both rates were several times higher than the rate in the New Jersey general population during this period (10.7-10.8/100,000).Conclusion:Although based on small numbers of patients with TB, we found a relatively high incidence of TB among hemodialysis patients in New Jersey. Most centers reported performing TSTs on workers but not on patients. These results suggest the need for improved TB screening and infection control precautions at outpatient dialysis centers.

The Long-term Effect of Bacille Calmette-Guérin Vaccination on Tuberculin Skin Testing

CHEST Journal ◽  
2017 ◽  
Vol 152 (2) ◽  
pp. 282-294 ◽  
Author(s):  
James D. Mancuso ◽  
Rupal M. Mody ◽  
Cara H. Olsen ◽  
Lee H. Harrison ◽  
Mathuram Santosham ◽  
...  
Keyword(s):  
Skin Testing ◽  
Term Effect ◽  
Tuberculin Skin Testing ◽  
Bacille Calmette Guerin ◽  
Long Term Effect

Ergonomic practices and musculoskeletal disorders among ophthalmologists in India: An online appraisal

2018 ◽  
Vol 30 (1) ◽  
pp. 196-200 ◽  
Author(s):  
Soujanya Kaup ◽  
Siddharudha Shivalli ◽  
Uma Kulkarni ◽  
Cynthia Arunachalam
Keyword(s):  
Confidence Interval ◽  
Musculoskeletal Disorders ◽  
Work Experience ◽  
Odds Ratio ◽  
Professional Training ◽  
Online Survey ◽  
Musculoskeletal Disorder ◽  
Productivity Loss ◽  
Validated Questionnaire ◽  
High Prevalence

Introduction: Ergonomics in ophthalmology is neither taught during professional training nor does it readily receive consideration or priority in clinical practice. Owing to a high prevalence of musculoskeletal disorders among ophthalmologists, ergonomic awareness, and practices are vital in averting this modern epidemic. Objective: To assess the ergonomic practices and prevalence of self-reported musculoskeletal disorders among ophthalmologists in India. Method: An online survey was conducted among ophthalmologists who were registered with the All India Ophthalmological Society of India using a pre-tested and validated questionnaire. Results: The prevalence of self-reported musculoskeletal disorder in the 377 participants was 75.3% (284; 95% confidence interval: 70.6–79.5). Low back pain (149, 52.9%) was the most commonly reported symptom. Musculoskeletal disorder–attributed productivity loss was reported by 58.45% (166) of the respondents. Musculoskeletal disorder was most frequently associated with less than 10 years of work experience (odds ratio: 1.2; 95% confidence interval: 1.1–1.3, p = 0.01) and lack of good clinic (odds ratio: 1.7; 95% confidence interval: 1.1–2.7, p = 0.03) and operation room ergonomic practices (odds ratio: 1.8; 95% confidence interval: 1.1–2.9, p = 0.03). Only 27.9% (105) of the respondents had accessed information related to ergonomics in ophthalmic practice. Conclusion: The self-reported musculoskeletal disorder among ophthalmologists in India is quite high and significant enough to cause some degree of productivity loss. It is thus imperative to emphasize the implementation of good ergonomic practices, especially among relatively young ophthalmologists.

scholarly journals High Prevalence of the CD14-159CC Genotype in Patients Infected with Severe Acute Respiratory Syndrome-Associated Coronavirus

2007 ◽  
Vol 14 (12) ◽  
pp. 1644-1645 ◽  
Author(s):  
Fang F. Yuan ◽  
Ingrid Boehm ◽  
Paul K. S. Chan ◽  
Katherine Marks ◽  
Julian W. Tang ◽  
...  
Keyword(s):  
Innate Immunity ◽  
Hong Kong ◽  
Severe Acute Respiratory Syndrome ◽  
Confidence Interval ◽  
Gene Polymorphism ◽  
Odds Ratio ◽  
Blood Donors ◽  
Genetic Factors ◽  
High Prevalence ◽  
Cd14 Gene

ABSTRACT To investigate whether genetic factors of innate immunity might influence susceptibility and/or progression in individuals infected with SARS, we evaluated the CD14 gene polymorphism in 198 Hong Kong blood donors and 152 Hong Kong severe acute respiratory syndrome (SARS) patients who were previously genotyped for FcγRIIA polymorphisms. The prevalence of the CD14-159CC polymorphism was significantly higher in the patients with severe SARS than in the those with mild SARS or controls (31% versus 15% [mild SARS] or 20% [controls]; mild SARS: P = 0.029; odds ratio, 2.74; 95% confidence interval, 1.15 to 6.57; controls, P = 0.04; odds ratio, 2.41; 95% confidence interval, 1.05 to 5.54), and both CD14-159CC and FcγRIIA-RR131 are risk genotypes for severe SARS-CoV infection.

Booster Effect of Two-Step Tuberculin Skin Testing Among Hospital Employees From Areas With a High Prevalence of Tuberculosis

2004 ◽  
Vol 25 (12) ◽  
pp. 1117-1120 ◽  
Author(s):  
Abdulrahman M. Al Mazrou
Keyword(s):  
Skin Testing ◽  
Age Groups ◽  
Baseline Survey ◽  
Tuberculin Skin Testing ◽  
Hospital Employees ◽  
High Prevalence ◽  
Booster Effect

AbstractDuring a baseline survey of TST, 236 nurses underwent a two-step TST. Overall, 29 (12%) showed boosting. All age groups showed boosting; the rate was 9.7% in those younger than 35 years. Subjects older than 45 years were more likely to have a booster effect than younger individuals (29% vs 10.1%).

Sign in / Sign up

Export Citation Format

Share Document