scholarly journals Therapeutic Interventions for HIV Infection and Chronic Viral Hepatitis

2005 ◽  
Vol 41 (Supplement_1) ◽  
pp. S69-S72 ◽  
Author(s):  
Curtis L. Cooper
Keyword(s):  
Hiv Infection ◽  
Viral Hepatitis ◽  
Chronic Viral Hepatitis ◽  
Therapeutic Interventions

Ritonavir Greatly Impairs CYP3A Activity in HIV Infection With Chronic Viral Hepatitis

2008 ◽  
Vol 49 (4) ◽  
pp. 358-368 ◽  
Author(s):  
Tamsin A Knox ◽  
Lauren Oleson ◽  
Lisa L von Moltke ◽  
Rhonda C Kaufman ◽  
Christine A Wanke ◽  
...  
Keyword(s):  
Hiv Infection ◽  
Viral Hepatitis ◽  
Chronic Viral Hepatitis ◽  
Cyp3a Activity

scholarly journals HIV-INFECTION AND CONSUMPTION OF PSYCHOACTIVE SUBSTANCES

2018 ◽  
Vol 23 (2) ◽  
pp. 60-67
Author(s):  
T. R. Petrosyan ◽  
Murad Z. Shakhmardanov
Keyword(s):  
Hepatitis B ◽  
Hiv Infection ◽  
Viral Hepatitis ◽  
Drug Users ◽  
Specific Treatment ◽  
Chronic Viral Hepatitis ◽  
Clinical Severity ◽  
Psychoactive Substances ◽  
Social Significance ◽  
Infected People

The article describes the main trends in the incidence rate of HIV infection in the Russian Federation over the past decade. The majority of HIV-infected people was shown to be injecting drug users. The immunosuppressive effect of psychoactive substances and peculiarities of HIV infection in drug-dependent patients are characterized. The drug use is considered to be associated with a high risk of co-infection: viral hepatitis via a parenteral transmission mechanism, tuberculosis. The spread of parenteral viral hepatitis among HIV-infected consumers of psychoactive substances has acquired a huge medical and social significance: hepatitis C affects more than 90% of consumers, hepatitis B - about 70-80%. Viral hepatitis B and C are considered as a co-factor in the tanatogenesis in babies of HIV-infected pregnant females, HIV/HCV coinfection accelerates the rate of progression of the chronic viral liver disease to liver cirrhosis and hepatocellular carcinoma. Among HIV-infected patients, there was significantly increased the proportion of cases killed by chronic viral hepatitis due to lack of the antiviral therapy for specific liver damage. Psychopathological changes in comorbid HIV infection in consumers of psychoactive substances are characterized. In drug users, HIV infection was noted to change the pathological attraction to psychoactive substances. If dependence on psychoactive substance was absent, this psychopathological phenomenon can suddenly arise in patients with narcological diseases, its clinical severity increases sharply. This is due to the general change in the unfavorable side of the mental state of patients, who were informed that they have HIV infection, given the low commitment of this contingent of ART proposed algorithm of complex medical and psychological care aimed at correcting mental, behavioral disorders and specific treatment of HIV infection.

scholarly journals Analysis of the causes of death in HIV-infected individuals in 2008-2010 according to the data of the clinical infectious diseases hospital named after S.P. Botkin, St. Petersburg

2012 ◽  
Vol 93 (3) ◽  
pp. 522-526 ◽  
Author(s):  
A G Rakhmanova ◽  
A A Yakovlev ◽  
M I Dmitrieva ◽  
T N Vinogradova ◽  
A A Kozlov
Keyword(s):  
Infectious Diseases ◽  
Hiv Infection ◽  
Viral Hepatitis ◽  
Causes Of Death ◽  
Mortality Rates ◽  
Chronic Viral Hepatitis ◽  
Concomitant Disease ◽  
Short Term ◽  
Number Of Patients ◽  
Short Term Mortality

Aim. To analyse the causes of death of individuals infected with the human immunodeficiency virus (HIV)/patients with acquired immunodeficiency syndrome (AIDS) in the Clinical Infectious Diseases Hospital named after S.P. Botkin in 2008-2010 taking into account the timing of disease, comorbidities, and clinical and laboratory data. Methods. The study included 439 HIV-infected individuals, who died in the Clinical Infectious Diseases Hospital named after S.P. Botkin in 2008-2010. Two groups of patients were identified: deaths from HIV/AIDS (n=306) and from other diseases (n=133, HIV infection was considered to be a concomitant disease). In both groups, analyzed were the short-term mortality rates, the presence of drugs and/or alcohol dependency, and the main causes of death (according to autopsy results). Results. In the group of patients who died of HIV-infection/AIDS and who did not receive antiretroviral therapy, generalized tuberculosis was diagnosed most often (65.7% of cases). Other rare diseases were pneumocystis pneumonia, cryptococcosis, cerebral toxoplasmosis, generalized fungal infection, cerebral lymphoma, and cytomegalovirus infection. The most frequent causes of death in the group of patients whose HIV-infection was considered to be a concomitant diseases were chronic viral hepatitis in the cirrhotic stage (42.9%) and septic thromboendocarditis, which were mainly diagnosed in social maladjusted patients: patients with alcoholism or intravenous drugs users. During evaluation of the short-term mortality rates it was established that 21 to 29% of patients in different years died on the 1st-3rd day after admission, which was related to extremely severe conditions of the patients. In Russia, including St. Petersburg, an annual increase in the number of new cases of HIV infection and increased mortality are registered, which indicates the severity of the epidemic and makes it possible to predict the increase in the number of patients requiring hospital treatment. Conclusion. The main causes of death among HIV-infected individuals in 2008-2010 were generalized tuberculosis and chronic viral hepatitis in the stage of cirrhosis; the high index of short-term mortality among HIV-infected patients suggests the need for measures for early detection of HIV-positive individuals and their medical examination, as well as an increase in the number of beds in order to provide specialized care to HIV-infected individuals in St. Petersburg.

scholarly journals LETHALITY OF TB PATIENTS, COMBINED WITH THE VIRAL HEPATITIS AND HIV INFECTION IN SAINT-PETERSBURG

2019 ◽  
Vol 11 (2) ◽  
pp. 42-47
Author(s):  
A. K. Ivanov ◽  
V. V. Nechaev ◽  
L. N. Pozhidayeva ◽  
V. B. Musatov ◽  
V. S. Belyakov ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis B ◽  
Hiv Infection ◽  
Viral Hepatitis ◽  
Fatal Outcome ◽  
Chronic Viral Hepatitis ◽  
Unknown Etiology ◽  
Saint Petersburg ◽  
Viral Hepatitis B ◽  
High Level

Сombination of tuberculosis and viral hepatitis have been registered 2525 newly identified patients in Saint-Petersburg for the period 2006–2017. Some of these patients have been infected with HIV. Fatal outcome in 625 (24,7%) was noted. Patients with tuberculosis and chronic viral hepatitis have had a combination of viral hepatitis B and C in 36% of cases. Patients with combination tuberculosis and chronic hepatitis of unknown etiology experienced a more frequent death (60%) than patients with combination tuberculosis and other chronic viral hepatitis. In patients with concurrent tuberculosis, chronic viral hepatitis and HIV infection, patients infected viral hepatitis B and C were 31,6%. In 160 patients with fatal outcomes had a combination of infections (tuberculosis, viral hepatitis and HIV infection), the mortality rate of persons with hepatitis of unknown etiology was the lowest (42%), compared with a group of individuals affected by viral hepatitis B and C simultaneously (83%). Among patients with tuberculosis, chronic hepatitis and HIV infection, the highest incidence of tuberculosis of the intrathoracic lymph nodes and disseminated pulmonary tuberculosis was registered. Lethal outcomes most often occur in individuals with advanced tuberculosis, in whom the secretion of mycobacteria tuberculosis into the external environment has not been established. Given the high level of mortality in patients with simultaneous defeat of tuberculosis, viral hepatitis and HIV infection, it is necessary to establish their centralized registration in order to study the epidemiological patterns and clinical features of co-infections.

Consensus conference on chronic viral hepatitis and HIV infection: updated Spanish recommendations

2004 ◽  
Vol 11 (1) ◽  
pp. 2-17 ◽  
Author(s):  
V. Soriano ◽  
J. M. Miro ◽  
J. Garcia-Samaniego ◽  
J. Torre-Cisneros ◽  
M. Nunez ◽  
...  
Keyword(s):  
Hiv Infection ◽  
Viral Hepatitis ◽  
Chronic Viral Hepatitis ◽  
Consensus Conference

scholarly journals Pandemic Influenza: Implications for Programs Controlling for HIV Infection, Tuberculosis, and Chronic Viral Hepatitis

2009 ◽  
Vol 99 (S2) ◽  
pp. S333-S339 ◽  
Author(s):  
James D. Heffelfinger ◽  
Pragna Patel ◽  
John T. Brooks ◽  
Helene Calvet ◽  
Charles L. Daley ◽  
...  
Keyword(s):  
Hiv Infection ◽  
Viral Hepatitis ◽  
Pandemic Influenza ◽  
Chronic Viral Hepatitis

Chronic viral hepatitis, HIV infection and Non‐Hodgkin Lymphomas in West Africa, a case‐control study

2021 ◽  
Author(s):  
Antoine Jaquet ◽  
Simon P. Boni ◽  
Kouakou Boidy ◽  
Judicaël Tine ◽  
Boris Tchounga ◽  
...  
Keyword(s):  
West Africa ◽  
Hiv Infection ◽  
Viral Hepatitis ◽  
Case Control Study ◽  
Case Control ◽  
Chronic Viral Hepatitis ◽  
Control Study
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