Chronic viral hepatitis, HIV infection and Non‐Hodgkin Lymphomas in West Africa, a case‐control study

2021 ◽  
Author(s):  
Antoine Jaquet ◽  
Simon P. Boni ◽  
Kouakou Boidy ◽  
Judicaël Tine ◽  
Boris Tchounga ◽  
...  
Keyword(s):  
West Africa ◽  
Hiv Infection ◽  
Viral Hepatitis ◽  
Case Control Study ◽  
Case Control ◽  
Chronic Viral Hepatitis ◽  
Control Study

scholarly journals Association of chronic viral hepatitis with ABO blood groups and rhesus (Rh) factor

2018 ◽  
Vol 6 (4) ◽  
pp. 1114 ◽  
Author(s):  
Hassan Abdullah Shakeel ◽  
Hamza Maqsood ◽  
Basit Ali ◽  
Ali Raza Khan
Keyword(s):  
Viral Hepatitis ◽  
Blood Donors ◽  
Case Control Study ◽  
Case Control ◽  
Chronic Viral Hepatitis ◽  
Blood Groups ◽  
Abo Blood Groups ◽  
Significant Difference ◽  
Group A ◽  
Control Study

Background: Chronic viral hepatitis includes hepatitis B and hepatitis C and is responsible for causing the deaths of millions of people all across the world each year. Although there are small studies in literature about association between ABO blood groups and chronic viral hepatitis, only few studies found relation between them. The objective of this case control study is to establish a relation between the host factors and these viral infections.Methods: This is a case control study on patients diagnosed with CVHB and CVHC. The study was conducted on 508 patients reported to Nishtar Hospital, Multan and Sheikh Zayd Hospital, Rahim Yar Khan, Pakistan.709 healthy blood donors were selected as a control group from Nishtar Hospital blood bank during December 2016 and December 2017.The results were subjected to SPSS v.20 for analysis using the chi square test. The patients and blood donors were also asked about certain demographic factors like age, sex and blood transfusions.Results: Among CVHB patients,173(100%), the distribution of blood groups was following: Group A, 38 (21.96%), B, 57 (32.94%), AB, 11 (6.35%), O, 67 (38.72%). 158 (91.32%) were Rh positive and 15 (8.67%) Rh negative. In CVHC patients, 335 (100%), the distribution was following: Group A, 69 (20.59%), B, 123 (36.71%), AB, 24 (7.16%), O, 119 (35.52%). 303 (90.44%) were Rh positive while 32 (9.55%) were Rh negative. In healthy blood donors, 167 (23.55%) were group A, 225 (31.73%) group B, 41(5.78%) group AB, 276 (38.92%) group O.632 (89.13%) were Rh positive and 77 (10.86%) Rh negative.Conclusions: There was no significant difference between blood groups(p>0.5) and Rh(p>0.5) with chronic viral hepatitis. However, it was also observed that the infections of HCV increase among (26-45) years old patients while the HBV infections increase with progression of age. Association of chronic viral hepatitis infection with blood group types needs more studies to get more knowledge about this aspect.

scholarly journals Genetic association of TOLLIP gene polymorphisms and HIV infection: a case-control study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Ming-Gui Wang ◽  
Jing Wang ◽  
Jian-Qing He
Keyword(s):  
Hiv Infection ◽  
Gene Polymorphisms ◽  
Case Control Study ◽  
Binary Logistic Regression ◽  
Case Control ◽  
Additive Models ◽  
Chinese Han ◽  
Interacting Protein ◽  
Control Study ◽  
Age And Sex

Abstract Background Previous studies have indicated that host genetic factors play an essential role in immunity to human immunodeficiency virus (HIV) infection. We aimed to investigate the association between the toll-interacting protein (TOLLIP) and mannose-binding lectin 2 (MBL2) genes and HIV infection susceptibility among Chinese Han patients. Methods This is a case-control study. A total of 435 HIV-infected patients and 1013 seronegative healthy individuals were recruited. DNA was extracted from whole blood. Two SNPs in the MBL2 gene (rs7096206 and rs1800450) and three SNPs in the TOLLIP gene (rs5743899, rs3750920, and rs5743867) were selected and genotyped using a SNPscan Kit (Cat#: G0104, Genesky Biotechnologies Inc., Shanghai, China). Odds ratios (ORs) and their 95% confidence intervals (CIs) were calculated using unconditional binary logistic regression. Results A significant association between the minor alleles rs5743899 (C allele) and rs5743867 (G allele) in the TOLLIP gene and susceptibility to HIV infection was found in this study after adjusting for age and sex (Pa = 0.011 and < 0.001, respectively). The rs5743867 in the TOLLIP gene was significantly associated with the risk of HIV infection in dominant, recessive, and additive models when adjusted for age and sex (Pa < 0.05). No significant association was found between MBL2 gene polymorphisms and HIV infection. Conclusion Our study found a statistically significant association between the two SNPs (rs5743867 and rs5743899) in the TOLLIP gene and susceptibility to HIV infection in a Chinese Han population.

scholarly journals Investigation of the risk factors for tuberculosis: a case–control study in three countries in West Africa

2005 ◽  
Vol 34 (4) ◽  
pp. 914-923 ◽  
Author(s):  
C Lienhardt ◽  
K Fielding ◽  
JS Sillah ◽  
B Bah ◽  
P Gustafson ◽  
...  
Keyword(s):  
Risk Factors ◽  
West Africa ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

scholarly journals HIV infection and sexual behaviour in primary and secondary infertile relationships: a case-control study in Kigali, Rwanda

2010 ◽  
Vol 87 (1) ◽  
pp. 28-34 ◽  
Author(s):  
N. Dhont ◽  
C. Muvunyi ◽  
S. Luchters ◽  
J. Vyankandondera ◽  
L. De Naeyer ◽  
...  
Keyword(s):  
Hiv Infection ◽  
Sexual Behaviour ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

scholarly journals Risk Factors Influencing HIV Infection Incidence in a Rural African Population: A Nested Case‐Control Study

2006 ◽  
Vol 193 (3) ◽  
pp. 458-466 ◽  
Author(s):  
James Todd ◽  
Heiner Grosskurth ◽  
John Changalucha ◽  
Angela Obasi ◽  
Frank Mosha ◽  
...  
Keyword(s):  
Risk Factors ◽  
Hiv Infection ◽  
Case Control Study ◽  
Case Control ◽  
African Population ◽  
Infection Incidence ◽  
Factors Influencing ◽  
Nested Case Control ◽  
Control Study

scholarly journals Individual, Partner, and Couple Predictors of HIV Infection among Pregnant Women in Malawi: A Case–Control Study

2017 ◽  
Vol 22 (6) ◽  
pp. 1775-1786 ◽  
Author(s):  
Nora E. Rosenberg ◽  
Lauren A. Graybill ◽  
Austin Wesevich ◽  
Nuala McGrath ◽  
Carol E. Golin ◽  
...  
Keyword(s):  
Hiv Infection ◽  
Pregnant Women ◽  
Case Control Study ◽  
Case Control ◽  
Control Study ◽  
Individual Partner
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