scholarly journals Loss of Red Blood Cell–Complement Regulatory Proteins and Increased Levels of Circulating Immune Complexes Are Associated with Severe Malarial Anemia

2003 ◽  
Vol 187 (3) ◽  
pp. 522-525 ◽  
Author(s):  
José A. Stoute ◽  
Alfred O. Odindo ◽  
Boaz O. Owuor ◽  
Erick K. Mibei ◽  
Malachi O. Opollo ◽  
...  
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Immune Complexes ◽  
Circulating Immune Complexes ◽  
Regulatory Proteins ◽  
Complement Regulatory Proteins ◽  
Severe Malarial Anemia ◽  
Malarial Anemia

scholarly journals Age‐Related Changes in Red Blood Cell Complement Regulatory Proteins and Susceptibility to Severe Malaria

2004 ◽  
Vol 190 (6) ◽  
pp. 1183-1191 ◽  
Author(s):  
John N. Waitumbi ◽  
Béatrice Donvito ◽  
Aymric Kisserli ◽  
Jacques H. M. Cohen ◽  
José A. Stoute
Keyword(s):  
Blood Cell ◽  
Severe Malaria ◽  
Red Blood Cell ◽  
Regulatory Proteins ◽  
Complement Regulatory Proteins ◽  
Age Related ◽  
Age Related Changes

scholarly journals COVID-19 and Thrombotic Thrombocytopenic Purpura: A Case Report

2021 ◽  
Author(s):  
Maryam Darnahal ◽  
Hamed Azhdari Tehrani ◽  
Mohammad Vaezi ◽  
Shirin Haghighi
Keyword(s):  
Case Report ◽  
Blood Cell ◽  
Thrombotic Thrombocytopenic Purpura ◽  
Organ Dysfunction ◽  
Red Blood Cell ◽  
Immune Complexes ◽  
Cell Injury ◽  
Coagulation Cascade ◽  
Thrombotic Microangiopathies ◽  
Thrombocytopenic Purpura

Endothelial injury by toxins, drugs, immune complexes leads to activation of coagulation cascade and thrombosis, which result in platelet consumption and red blood cell injury. These thrombotic microangiopathies can potentially injure numerous organs and result in organ dysfunction. In this case, we present the fourth reported patient with thrombotic thrombocytopenic purpura associated with COVID-19.

Factors Increasing red Blood Cell Aggregation in Men with Coronary Artery Disease

1979 ◽  
Author(s):  
N. Boss ◽  
W. Bruder ◽  
M. Bierner ◽  
S. Koenig - Erich ◽  
E. Fleck ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Blood Cell ◽  
Red Blood Cell ◽  
Immune Complexes ◽  
Cell Aggregation ◽  
Coagulation System ◽  
Red Blood Cell Aggregation ◽  
Artery Disease ◽  
Blood Cell Aggregation

Red blood cell aggregation value (AW) was found to be of good diagnostic value ror coronary artery disease. Causes of increased aggregation value were investigated by means of protein analytical methods and standard laboratory techniques in 41 men with angiographically documented coronary artery disease. Best correlation coefficients were found between the red blood cell aggregation value and IgG, precipitable by 25g/1 polyethyleneglycol 6000 (r = 0.536; 2P ≤ 0.001). In coronary artery disease patients with no previous myocardial infarction (N=15) polyethyleneglycol precipitable IgM was found to correlate best with red blood cell aggregation (r = 0.707; 2P ≤ ! 0.01 ). In contrast to these results, patients without coronary stenosis demonstrated no significant correlation between the red blood cell aggregation value and the latter factorsThese results indicate a possible link between coronary artery disease, immune complexes and red blood cell aggregation. Platelet aggregation, as well as the coagulation system may also be influenced by these possibly specific immune complexes.

scholarly journals The relationship between systemic iron homeostasis and erythropoiesis

2017 ◽  
Vol 37 (6) ◽  
Author(s):  
Gautam Rishi ◽  
V. Nathan Subramaniam
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Iron Homeostasis ◽  
Iron Absorption ◽  
Current Knowledge ◽  
The Body ◽  
Regulatory Proteins ◽  
Transferrin Receptors ◽  
Cell Production ◽  
The Relationship

Red blood cell production (erythropoiesis) is the single largest consumer of iron in the body; this need is satisfied by maintaining a sensitive regulation of iron levels. The level of erythropoietic demand regulates the expression of the iron hormone hepcidin and thus iron absorption. Erythropoiesis-mediated regulation of hepcidin is an area of increasing importance and recent studies have identified a number of potential regulatory proteins. This review summarizes our current knowledge about these candidate erythroid regulators of hepcidin and the relation between transferrin receptors and erythropoiesis.

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