scholarly journals Age‐Related Changes in Red Blood Cell Complement Regulatory Proteins and Susceptibility to Severe Malaria

2004 ◽  
Vol 190 (6) ◽  
pp. 1183-1191 ◽  
Author(s):  
John N. Waitumbi ◽  
Béatrice Donvito ◽  
Aymric Kisserli ◽  
Jacques H. M. Cohen ◽  
José A. Stoute
Keyword(s):  
Blood Cell ◽  
Severe Malaria ◽  
Red Blood Cell ◽  
Regulatory Proteins ◽  
Complement Regulatory Proteins ◽  
Age Related ◽  
Age Related Changes

Age-Related Changes in Red Blood Cell Lipids

Angiology ◽  
1991 ◽  
Vol 42 (4) ◽  
pp. 316-322 ◽  
Author(s):  
Domenico Prisco ◽  
Pier Giorgio Rogasi ◽  
Rita Paniccia ◽  
Rosanna Abbate ◽  
Gian Franco Gensini
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Age Related ◽  
Age Related Changes

Effect of age and gender on reference intervals of red blood cell distribution width (RDW) and mean red cell volume (MCV)

2015 ◽  
Vol 53 (12) ◽  
Author(s):  
Johannes J.M.L. Hoffmann ◽  
Karin C.A.M. Nabbe ◽  
Nicole M.A. van den Broek
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Reference Intervals ◽  
Cell Distribution ◽  
Age Dependency ◽  
Distribution Width ◽  
Age Related ◽  
Age Dependent ◽  
Red Blood Cell Distribution ◽  
Related Increase

AbstractRed blood cell distribution width (RDW) was recently shown to be age-dependent when using Sysmex XE-2100 hematology analyzers. As measuring RDW is subject to technology, we have investigated if this relation also exists when using a different hematology analyzer, Abbott CELL-DYN Sapphire. In addition, as RDW is generally expressed relative to mean red blood cell volume (MCV), we have explored how MCV influences the age-dependency of RDW.We measured RDW and MCV in a large cohort and calculated RDW-SD (the “absolute” RDW), which does not contain MCV. For establishing reference intervals we used Bhattacharya statistics.In our study cohort of 8089 individuals we found a strong association between RDW and age, but not with gender. Also MCV showed an age-related increase over the entire age range. The conventional RDW increased by 6% from the youngest to oldest age class, whereas RDW-SD increased by nearly 15%. This difference was caused by a mean age-related increase in MCV of 6.6%. Age-dependent reference intervals were established for RDW, RDW-SD and MCV.The age-dependency of RDW seems to be a universal biological feature rather than related with a single type of hematology analyzer. As not only RDW, but also MCV increases with age, we propose that future studies on the prognostic significance of RDW take its age-dependency into account and focus on RDW-SD as a potential marker of adverse events in many clinical conditions.

scholarly journals An imbalance of human complement regulatory proteins CFHR1, CFHR3 and factor H influences risk for age-related macular degeneration (AMD)

2010 ◽  
Vol 19 (23) ◽  
pp. 4694-4704 ◽  
Author(s):  
Lars G. Fritsche ◽  
Nadine Lauer ◽  
Andrea Hartmann ◽  
Selina Stippa ◽  
Claudia N. Keilhauer ◽  
...  
Keyword(s):  
Macular Degeneration ◽  
Factor H ◽  
Age Related Macular Degeneration ◽  
Regulatory Proteins ◽  
Human Complement ◽  
Complement Regulatory Proteins ◽  
Age Related

Abnormal Blood Flow and Red Blood Cell Deformability in Severe Malaria

2000 ◽  
Vol 16 (6) ◽  
pp. 228-232 ◽  
Author(s):  
Arjen M Dondorp ◽  
Piet A Kager ◽  
Johan Vreeken ◽  
Nicholas J White
Keyword(s):  
Blood Flow ◽  
Blood Cell ◽  
Severe Malaria ◽  
Red Blood Cell ◽  
Cell Deformability ◽  
Red Blood Cell Deformability

Gestational age-related changes in the peripheral blood cell composition of sub-Saharan African women

2013 ◽  
Vol 98 (1-2) ◽  
pp. 21-28 ◽  
Author(s):  
Samad Ibitokou ◽  
Laurent Brutus ◽  
Bertin Vianou ◽  
Mayke Oesterholt ◽  
Achille Massougbodji ◽  
...  
Keyword(s):  
Blood Cell ◽  
Gestational Age ◽  
Peripheral Blood ◽  
Peripheral Blood Cell ◽  
African Women ◽  
Cell Composition ◽  
Age Related ◽  
Sub Saharan ◽  
Age Related Changes
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