Quantitative studies of the interaction of 3H-dsDNA/anti-DNA immune complexes with complement: Comparison and evaluation of the Raji cell, the solution phase C1q, and the red blood cell linked complement fixation radioimmunoassays

1981 ◽  
Vol 1 (1) ◽  
pp. 29-34 ◽  
Author(s):  
R. P. Taylor ◽  
B. S. Andrews ◽  
K. W. Morley ◽  
T. Conlon
Author(s):  
Maryam Darnahal ◽  
Hamed Azhdari Tehrani ◽  
Mohammad Vaezi ◽  
Shirin Haghighi

Endothelial injury by toxins, drugs, immune complexes leads to activation of coagulation cascade and thrombosis, which result in platelet consumption and red blood cell injury. These thrombotic microangiopathies can potentially injure numerous organs and result in organ dysfunction. In this case, we present the fourth reported patient with thrombotic thrombocytopenic purpura associated with COVID-19.


1979 ◽  
Author(s):  
N. Boss ◽  
W. Bruder ◽  
M. Bierner ◽  
S. Koenig - Erich ◽  
E. Fleck ◽  
...  

Red blood cell aggregation value (AW) was found to be of good diagnostic value ror coronary artery disease. Causes of increased aggregation value were investigated by means of protein analytical methods and standard laboratory techniques in 41 men with angiographically documented coronary artery disease. Best correlation coefficients were found between the red blood cell aggregation value and IgG, precipitable by 25g/1 polyethyleneglycol 6000 (r = 0.536; 2P ≤ 0.001). In coronary artery disease patients with no previous myocardial infarction (N=15) polyethyleneglycol precipitable IgM was found to correlate best with red blood cell aggregation (r = 0.707; 2P ≤ ! 0.01 ). In contrast to these results, patients without coronary stenosis demonstrated no significant correlation between the red blood cell aggregation value and the latter factorsThese results indicate a possible link between coronary artery disease, immune complexes and red blood cell aggregation. Platelet aggregation, as well as the coagulation system may also be influenced by these possibly specific immune complexes.


1963 ◽  
Vol 42 (11) ◽  
pp. 1790-1801 ◽  
Author(s):  
M. Constantoulakis ◽  
N. Costea ◽  
R. S. Schwartz ◽  
W. Dameshek

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