Geographic Patterns of Genetic Variation in Pinus monticola

1984 ◽  
Vol 145 (2) ◽  
pp. 229-239 ◽  
Author(s):  
G. E. Rehfeldt ◽  
R. J. Hoff ◽  
R. J. Steinhoff
2020 ◽  
Author(s):  
Arjun Biddanda ◽  
Daniel P. Rice ◽  
John Novembre

AbstractA key challenge in human genetics is to describe and understand the distribution of human genetic variation. Often genetic variation is described by showing relationships among populations or individuals, in each case drawing inferences over a large number of variants. Here, we present an alternative representation of human genetic variation that reveals the relative abundance of different allele frequency patterns across populations. This approach allows viewers to easily see several features of human genetic structure: (1) most variants are rare and geographically localized, (2) variants that are common in a single geographic region are more likely to be shared across the globe than to be private to that region, and (3) where two individuals differ, it is most often due to variants that are common globally, regardless of whether the individuals are from the same region or different regions. To guide interpretation of the results, we also apply the visualization to contrasting theoretical scenarios with varying levels of divergence and gene flow. Our variant-centric visualization clarifies the major geographic patterns of human variation and can be used to help correct potential misconceptions about the extent and nature of genetic differentiation among populations.


2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Kenneth K. Kidd ◽  
Andrew J. Pakstis ◽  
Michael P. Donnelly ◽  
Ozlem Bulbul ◽  
Lotfi Cherni ◽  
...  

Abstract Oculocutaneous Albinism type 2 (OCA2) is a gene of great interest because of genetic variation affecting normal pigmentation variation in humans. The diverse geographic patterns for variant frequencies at OCA2 have been evident but have not been systematically investigated, especially outside of Europe. Here we examine population genetic variation in and near the OCA2 gene from a worldwide perspective. The very different patterns of genetic variation found across world regions suggest strong selection effects may have been at work over time. For example, analyses involving the variants that affect pigmentation of the iris argue that the derived allele of the rs1800407 single nucleotide polymorphism, which produces a hypomorphic protein, may have contributed to the previously demonstrated positive selection in Europe for the enhancer variant responsible for light eye color. More study is needed on the relationships of the genetic variation at OCA2 to variation in pigmentation in areas beyond Europe.


2007 ◽  
Vol 45 (11-12) ◽  
pp. 839-856 ◽  
Author(s):  
Gustavo B. Miranda ◽  
Jaqueline Andrades-Miranda ◽  
Luiz F. B. Oliveira ◽  
Alfredo Langguth ◽  
Margarete S. Mattevi

2011 ◽  
Vol 13 (2) ◽  
pp. 475-498 ◽  
Author(s):  
Kevin M. Potter ◽  
Robert M. Jetton ◽  
William S. Dvorak ◽  
Valerie D. Hipkins ◽  
Rusty Rhea ◽  
...  

2013 ◽  
Vol 300 (6) ◽  
pp. 1313-1322 ◽  
Author(s):  
Jun-Jun Liu ◽  
Danelle Chan ◽  
Rona Sturrock ◽  
Richard A. Sniezko

2019 ◽  
Vol 9 (6) ◽  
pp. 3389-3404 ◽  
Author(s):  
Joseph W. Hinton ◽  
Elizabeth Heppenheimer ◽  
Kyla M. West ◽  
Danny Caudill ◽  
Melissa L. Karlin ◽  
...  

2011 ◽  
Vol 7 (5) ◽  
pp. 917-932 ◽  
Author(s):  
L. J. Grauke ◽  
Maria Azucena Mendoza-Herrera ◽  
Allison J. Miller ◽  
Bruce. W. Wood

1993 ◽  
Vol 23 (9) ◽  
pp. 1930-1939 ◽  
Author(s):  
A. A. Ager ◽  
P. E. Heilman ◽  
R. F. Stettler

Genetic variation was examined within and among populations of red alder (Alnusrubra Bong.) from elevational gradients in four river drainages of the Pacific Northwest. Wind-pollinated progenies of 120 trees were grown for 3 years in a common garden environment and measured for growth and shoot phenology. Variation in top weight, bud flush, and leaf abscission was analyzed in relation to native climate and elevation and compared with sympatric species. Strong geographic patterns of variation were observed for all measured traits, apparently reflecting adaptations to highly variable climates within the region studied. Growth traits were correlated with temperature amplitude and length of growing season. Growth rhythm in bud flushing and growth cessation was related to two important environmental cues, spring thermal sums and fall frost dates. Overall levels of variation in red alder appeared to be similar to several sympatric conifers, although variation within populations of red alder was lower. The latter finding may be due to the demography of the riparian populations sampled, or perhaps a characteristic of the species and its colonizing life history.


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