scholarly journals ETUDE QUANTITATIVE PAR RADIOAUTOGRAPHIE AU MICROSCOPE ELECTRONIQUE DE L'UTILISATION DE LA DL-LEUCINE-3H PAR LES CELLULES DE L'HYPOPHYSE DU CANARD EN CULTURE ORGANOTYPIQE

1967 ◽  
Vol 35 (3) ◽  
pp. 501-519 ◽  
Author(s):  
A. Tixier-Vidal ◽  
R. Picart

The synthesis, intracellular transport, storing, and excretion of proteins by duck hypophyseal cells in organ culture were studied with tritiated DL-leucine and high resolution radioautography (pulse-labeling experiments). Quantitative study of the radioautographs allowed a determination of the relative proportions of cytoplasmic radioactivity located in each cellular compartment (ergastoplasm, Golgi apparatus, and protein granules) as well as the variations in these proportions as a function of time. The number of labeled protein granules as opposed to the total number of granules in the cell was also determined (RSg). These data were separately analyzed for the two types of cells present in the explants: prolactin cells and "MSH" cells. The synthetic process follows a course common to both cell types, each of which is distinguished by its particular modalities. The labeled proteins, synthesized within several minutes in the ergastoplasm, are concentrated in the Golgi zone within 30 min. They then migrate out of this area, the emptying of which is accomplished in about 4 hr. These proteins become equally distributed between the protein granules, on the one hand, and the cytoplasm ("sedentary" proteins), on the other. The RSg reaches its maximum when the Golgi zone is emptied, but this figure remains very low (3%). The RSg then decreases slowly (1% in 40 hr). It is concluded that hypophyseal cells are able to store protein in their granules and that their processes of synthesis and excretion are not continuous. The prolactin cells differ from the "MSH" cells in that they have a slower migration of newly synthesized proteins, and these proteins pass via the dilated ergastoplasmic cisterns in which they may possibly be stored.

1975 ◽  
Vol 68 ◽  
pp. 239-241
Author(s):  
John C. Brown ◽  
H. F. Van Beek

SummaryThe importance and difficulties of determining the height of hard X-ray sources in the solar atmosphere, in order to distinguish source models, have been discussed by Brown and McClymont (1974) and also in this Symposium (Brown, 1975; Datlowe, 1975). Theoretical predictions of this height, h, range between and 105 km above the photosphere for different models (Brown and McClymont, 1974; McClymont and Brown, 1974). Equally diverse values have been inferred from observations of synchronous chromospheric EUV bursts (Kane and Donnelly, 1971) on the one hand and from apparently behind-the-limb events (e.g. Datlowe, 1975) on the other.


Antichthon ◽  
1985 ◽  
Vol 19 ◽  
pp. 57-67 ◽  
Author(s):  
W.K. Lacey
Keyword(s):  
The One ◽  

While the exact meaning of Res Gestae 34, the powers of Augustus at various moments in his principate, and the significance of his auctoritas have been extensively argued, more practical questions about how his political arrangements might have been set into action have not generally excited much interest. In 1974 I put forward a suggestion about how the so-called first settlement of 27 B.C. came about. It was, in brief, that Octavian, as he then was, used the traditional consular mechanisms, and proposed for debate in the Senate a motion, de provinciis consularibus, and this explains why, on the one hand, the result of the debate was that he had provinces allocated to him, and, on the other, claims could be made that the res publica was restored, because one of the things which characterized res publica (as distinct from dictatorship or triumviral rule) was that the determination of who should command which army stationed in the provinces now lay, ostensibly at least, with the publicum consilium, the Senate.


Table II : Quantitative determination of carbonyl compounds at different odour sources (concentrations in ppb) Rendering plant Gelatine plant neighbourhood neighbourhood Formaldehyde 40 16 Acetaldehyde 39 24 Acetone 36 73 Prcpanal 10 -Isobutyraldehyde 10 30 Pentanal 15 19 Hexanal 3.52 Heptanal 12.5 Octanal 10.5 Nonanal 1 2 acids (figure 7). However extractions always involve a serious decrease in sensitivity, while evaporation of the extract produces a solution in 0.1-0.5 ml of solvent, and only 1 pi of it can be brought in the gas chromatograph. Therefore work is in progress to enhance sensitivity by converting acids in­ to halogenated derivatives, which can be GC-analysed with the more sensitive electron-capture detector. For thiols a similar procedure is investigated as with aldehydes. One possibility is absorption of thiols in an alkaline solution and reaction with 2,4-dinitrochlorobenzene, yielding 2,4-dinitrofenylsulfides, which are analysed by HPLC (9). Sane improvements on removal of reagents at the one hand and on separation of sane by-products on the other hand have to be achieved in order to in­ crease the sensitivity with another factor of ten. 5. CONCLUSION The actual scope and limitations of chemical analysis of odour show that all problems can be tackled as far as emission is concerned. For iititiission measurements seme progress is necessary, but there is no essential reason why chemical analysis would be unable to attain the desired sensitivity for all types of odorants. There is no doubt that in a few years the last dif­ ficulties will be solved. In order to achieve real control of odour nui­ sance, automatic measurement is necessary on a long time basis. There again seme technical development is to be expected. Does this mean that machines are going to decide if an odour is pre­ sent or not? By no means, while the population will always be the reference, and psychophysical measurements will be necessary to make chemical analysis possible.


2013 ◽  
Vol 2013 ◽  
pp. 1-16 ◽  
Author(s):  
Silja Raschke ◽  
Jürgen Eckel

This review summarizes the current literature regarding the most discussed contraction-regulated moykines like IL-6, IL-15, irisin, BDNF, ANGPTL4, FGF21, myonectin and MCP-1. It is suggested that the term myokine is restricted to proteins secreted from skeletal muscle cells, excluding proteins that are secreted by other cell types in skeletal muscle tissue and excluding proteins which are only described on the mRNA level. Interestingly, many of the contraction-regulated myokines described in the literature are additionally known to be secreted by adipocytes. We termed these proteins adipo-myokines. Within this review, we try to elaborate on the question why pro-inflammatory adipokines on the one hand are upregulated in the obese state, and have beneficial effects after exercise on the other hand. Both, adipokines and myokines do have autocrine effects within their corresponding tissues. In addition, they are involved in an endocrine crosstalk with other tissues. Depending on the extent and the kinetics of adipo-myokines in serum, these molecules seem to have a beneficial or an adverse effect on the target tissue.


1831 ◽  
Vol 121 ◽  
pp. 417-422 ◽  

That several of the planets as well as that which we inhabit are surrounded by atmosphere, astronomical observations have long since established; the extent, however, to which in particular planets such atmospheres are diffused, is as yet not satisfactorily determined. The former rests principally upon phenomena observed on the planets’ discs, whilst the latter derives its support chiefly from those detected at or near their respective limbs. Every night, nay almost every hour, may give us indication of the one, whilst years are sometimes necessary, as in the case of planets unattended by satellites, to help us to the other; thus the hypothesis of the extensive atmosphere of Mars derives its origin from the observations of Cassini and Roëmer, and has stood more than a century and a half without refutation or support. The observations to which I allude formed part of a series undertaken for the determination of the parallax of Mars, and are recorded in the Mémoires de l’Académie des Sciences. Cassini’s were made at Briare and at La Charité sur Loire; whilst Roémer’s was obtained at the Royal Observatory of Paris.


1970 ◽  
Vol 16 (2) ◽  
pp. 107-115 ◽  
Author(s):  
Gerald R. Taylor ◽  
Rufus K. Guthrie ◽  
Elwood B. Shirling

A dichotomous key for determination of serological groups among Streptomyces is described. This key is limited in that only seven specific antisera are used for testing. The utility and reliability of the application of this key were tested and compared to the results of previous taxonomic studies reported on the basis of biochemical and morphological characteristics of these organisms. Results indicate the desirability of using a combination of methods including serological characteristics on the one hand, and biochemical–morphological characteristics on the other, to increase the reliability of taxonomic studies.


1826 ◽  
Vol 10 (1) ◽  
pp. 127-147
Author(s):  
W. Haidinger

The following paper contains the results of a series of inquiries, which lead to the conclusion, that the mineral called Smaragdite by Saussure, does not form a species of its own; but that this name has been given to a compound of certain varieties of two distinct species, Augite and Hornblende, the natural-historical species of paratomous and hemiprismatic Augite-spar.Owing in part to the slight degree of resemblance prevailing among its varieties, the authors who have described them differ so essentially in opinion, that I am obliged to go into various details, both respecting the external appearance of the mineral itself, and of the opinions of mineralogists, in order to afford a correct view of the natural-historical species, to which these varieties belong, since this is the basis upon which every system, and, indeed, all accurate information in natural history, is founded, and the fixed point to which the one and the other must be referred.


1930 ◽  
Vol 24 (2) ◽  
pp. 310-336 ◽  
Author(s):  
Ralph A. Nohem

Much controversy has raged for a long period of time over the precise nature of what Wormser refers to as the “anatomy” of a corporation. Wormser himself defines a corporation as a “group of one or more persons authorized by sovereign authority to act as a unit and a personality in the eye of the law.” The definition indicates, on the one hand, that the act of incorporation creates a new person or entity, on the other that this new entity is in fact composite, made up of one or more pre-existing entities. The question arises, at what times will the court regard the corporate entity, and at what times will it look to the real persons who compose it ? A key to the solution of the problem is offered by Lord Mansfield. “A fiction of law shall never be contradicted so as to defeat the end for which it was invented, but for every other purpose it may be contradicted.” By the separate entity theory is meant that a corporation is to be regarded as an entity separate and apart from its corporators and that it is to be treated like any other independent person. That this is the theory of corporations generally accepted by the courts need hardly be proved. It will only be noted that the ruling English case on the subject is that of Salomon and Co. v. Salomon. In his opinion in that case Lord Halsbury said: “Once the company is legally incorporated it must be treated like any other independent person.”


2002 ◽  
Vol 45 (4) ◽  
pp. 622-627
Author(s):  
Kazem Lotfipour-Saedi

Abstract Various definitions have been offered for translation, each assuming a different orientation to the nature of meaning and language but all sharing the notion of replacement of one sort or another. The commonsensically perceived framework of translation operation is also basically founded upon the notion of replacement, mostly leading to the illusion that translation is just a matter of replacing SL elements by TL ones. But due to the uniqueness of each language system on the one hand and the non-isomorphic nature of the relationship between form and meaning across language on the other, this replacement operation faces challenging problems. This paper argues that there is no direct route in this operation and the replacement becomes possible only through the determination of the value of the elements to be replaced.


Author(s):  
Erma Ivoš

In this article the author points some actual questions of the transformation process in the Croatian society. The analysis of Z. Brzezinski is used as analytical model which basic function is of strategic meaning. The idea was to show how Croatia is close or distant from the mainstream of transformation process. The conclusion is that the successful achievements of the transformation depends both on the influence of the International community, political and economic on the one side and on the nature of the postcomunist self-determination of Croatian society, on the other side.98


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