scholarly journals A KINETIC STUDY OF THE NEURON-GLIA RELATIONSHIP

1962 ◽  
Vol 13 (2) ◽  
pp. 233-237 ◽  
Author(s):  
Holger Hydén ◽  
Paul W. Lange
Keyword(s):  
Kinetic Study ◽  
Nerve Cell ◽  
Glial Cells ◽  
Vestibular Nucleus ◽  
Kinetic Studies ◽  
Nerve Cells ◽  
Enzyme Complex ◽  
Lateral Vestibular Nucleus

Kinetic studies have been performed on the activity of the succinate oxidizing enzyme complex in living nerve cells and glial cells after increasing duration of stimulation. The nerve cells and glia of the lateral vestibular nucleus were used. The results show a clear difference between the neuron and its surrounding glia. The nerve cell reacted by highly increasing the capacity of the electron transporting system, reflecting an increased consumption of energy as a function of the stimulation. The glia, in contrast, did not change in this respect.

scholarly journals STUDIES ON PSEUDORABIES (INFECTIOUS BULBAR PARALYSIS, MAD ITCH)

1933 ◽  
Vol 58 (4) ◽  
pp. 415-433 ◽  
Author(s):  
E. Weston Hurst
Keyword(s):  
Nerve Cell ◽  
Glial Cells ◽  
Nerve Cells ◽  
Spinal Ganglia ◽  
Cell Degeneration ◽  
Intracerebral Inoculation ◽  
Bulbar Paralysis ◽  
Nuclear Alterations ◽  
Cardinal Symptom ◽  
In Cells

The histology of pseudorabies differs materially in various animal species. In the rabbit, subcutaneous, intradermal or intramuscular inoculation leads to local inflammation and necrosis. The infection ascends the peripheral nerve (possibly both interstitially and by the axis-cylinders) to the corresponding spinal ganglia and segments of the spinal cord, where primary degeneration of nerve and glial cells takes place. The nerve cell changes are probably responsible for the cardinal symptom of the disease, itching. Death ensues soon after virus reaches the medulla, before visible changes have been produced here. Intracerebral inoculation is followed by characteristic lesions in the meninges, in subpial glial cells and in superficially placed nerve cells. Morbid changes in the lungs are not necessarily related to the presence of virus, but specific lesions may be present. Intranuclear inclusions bearing some resemblance to those in herpetic encephalitis, yellow fever, etc., occur in cells derived from all embryonic layers. The disease in the guinea pig resembles closely that in the rabbit and is modified only by the slightly greater resistance of the animal. In the monkey after intracerebral inoculation, widespread degeneration and necrosis of cortical nerve cells are accompanied by the appearance of specific nuclear alterations in nerve and glial cells, but not in cells of mesodermal origin. No lesions are found in other viscera. In the spontaneous disease in the cow lesions approximate more closely to those in the monkey than to those in the rabbit. In the pig vascular and interstitial lesions predominate, nerve cell degeneration is relatively slight and typical inclusions are not observed. These differences probably explain the benign course of the malady following subcutaneous inoculation in this animal. The lymphatic system, too, participates in the reaction to the virus.

An Ultrastructural Study of the Lateral Vestibular Nucleus in the Rat: Changes in Glial Cells Following Partial Deafferentation

1973 ◽  
Vol 31 ◽  
pp. 658-659
Author(s):  
J. E. Johnson
Keyword(s):  
Corpus Callosum ◽  
Glial Cells ◽  
Ultrastructural Study ◽  
Vestibular Nucleus ◽  
Vestibular Nuclei ◽  
Lateral Vestibular Nucleus ◽  
Light Medium

Mori and Leblond have reported that oligodendrocytes in the corpus callosum of rats may be classified into three types consisting of light, medium and dark. The light oligodendrocytes are the largest, and the dark ones are the smallest. In the present study, oligodendrocytes of different sizes and densities were found to occur in the normal lateral vestibular nucleus of the rat. Here, as reported in the corpus callosum, the darkest cells are the smallest. The largest of the oligodendrocytes in the lateral vestibular nucleus have a density which approaches that of astrocytes, which are also present throughout the nucleus.The lateral vestibular nuclei of 18 rats were partially deaffer-entated by aspirating the anterior vermis of the cerebellum, from which the nucleus receives input.

scholarly journals EXPERIMENTALLY INDUCED CHANGES IN THE BASE COMPOSITION OF THE RIBONUCLEIC ACIDS OF ISOLATED NERVE CELLS AND THEIR OLIGODENDROGLIAL CELLS

1961 ◽  
Vol 10 (3) ◽  
pp. 403-410 ◽  
Author(s):  
Endre Egyházi ◽  
Holger Hydén
Keyword(s):  
Protein Content ◽  
Nerve Cell ◽  
Glial Cells ◽  
Base Composition ◽  
Functional Relationship ◽  
Nerve Cells ◽  
Ribonucleic Acids ◽  
Cent Increase ◽  
The Difference ◽  
Induced Changes

The effect of tricyano-amino-propene, a dimer of malononitrile, on the base composition of the RNA in isolated Deiters' nerve cells and their oligodendroglial cells has been studied using a microelectrophoretic method. Tri-a-p in a dose of 20 mg/kg has the effect of increasing the RNA and protein content per nerve cell by 25 per cent and decreasing the glia RNA by 45 per cent. The RNA base composition of the nerve cells from the control animals differs from that of their glial cells. The guanine of the nerve cell is significantly higher than that of the glia, but the content of cytosine is higher in the glia than in the RNA of nerve cell. The cytosine of nerve cells decreased significantly after tri-a-p administration. In the glial cells the cytosine showed a 20 per cent increase, and the guanine a 25 per cent decrease. Tri-a-p sharpened the difference in RNA composition already existing between the control nerve cells and their glial cells by almost 300 per cent for the guanine and by 400 per cent for the cytosine. The chemical and functional relationship between the nerve cell and its oligodendroglial cells is discussed.

A.F. De Mezer Posthumous changes in nerve cells, detected by staining according to Nissl. —University Izvestiya. 1900, August, No.8

1901 ◽  
Vol IX (1) ◽  
pp. 208-209
Author(s):  
B. Vorotynsky
Keyword(s):  
Nerve Cell ◽  
Nerve Cells ◽  
The University

The work was carried out in the laboratory of the pathological anatomical institute of the University of St. Vladimira. First, the author describes the structure of the nerve cell, which is detected by staining by the Nissl method, and he separately stops at describing the structure of the processes, nucleus and nucleolus.

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